Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Julia M. Adler"'
Autor:
Julia M. Adler, Ricardo Martin Vidal, Christine Langner, Daria Vladimirova, Azza Abdelgawad, Daniela Kunecova, Xiaoyuan Lin, Geraldine Nouailles, Anne Voss, Sandra Kunder, Achim D. Gruber, Haibo Wu, Nikolaus Osterrieder, Dusan Kunec, Jakob Trimpert
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The development of effective SARS-CoV-2 vaccines has been essential to control COVID-19, but significant challenges remain. One problem is intramuscular administration, which does not induce robust mucosal immune responses in the upper airwa
Externí odkaz:
https://doaj.org/article/ba2f95e791cc4727ac5174ea84be9eaa
Autor:
Stefan Peidli, Geraldine Nouailles, Emanuel Wyler, Julia M. Adler, Sandra Kunder, Anne Voß, Julia Kazmierski, Fabian Pott, Peter Pennitz, Dylan Postmus, Luiz Gustavo Teixeira Alves, Christine Goffinet, Achim D. Gruber, Nils Blüthgen, Martin Witzenrath, Jakob Trimpert, Markus Landthaler, Samantha D. Praktiknjo
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114328- (2024)
Summary: A key issue for research on COVID-19 pathogenesis is the lack of biopsies from patients and of samples at the onset of infection. To overcome these hurdles, hamsters were shown to be useful models for studying this disease. Here, we further
Externí odkaz:
https://doaj.org/article/c99d11239614470a8f8f7a476d42cda0
Autor:
Susanne Herwig, Julia M. Adler, Daria Vladimirova, Jakob Trimpert, Jalid Sehouli, Günter Cichon
Publikováno v:
Vaccines, Vol 12, Iss 3, p 248 (2024)
During the COVID-19 pandemic, the early emergence of viral variants repeatedly undermined the effects of vaccination. Our aim here is to explore strategies for improving spike vaccine gene antigenicity by merging mutations from different variants of
Externí odkaz:
https://doaj.org/article/3cd5b0c233ae4bbb92fbbcc8550a71b6
Autor:
Jackson Emanuel, Jan Papies, Celine Galander, Julia M. Adler, Nicolas Heinemann, Kathrin Eschke, Sophie Merz, Hannah Pischon, Ruben Rose, Andi Krumbholz, Žarko Kulić, Martin D. Lehner, Jakob Trimpert, Marcel A. Müller
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The occurrence of immune-evasive SARS-CoV-2 strains emphasizes the importance to search for broad-acting antiviral compounds. Our previous in vitro study showed that Pelargonium sidoides DC. root extract EPs® 7630 has combined antiviral and immunomo
Externí odkaz:
https://doaj.org/article/044307d14f644aaf80e4e9beb57d435d
Autor:
Mohammed O. Abdelaziz, Martin J. Raftery, Julian Weihs, Olivia Bielawski, Richard Edel, Julia Köppke, Daria Vladimirova, Julia M. Adler, Theresa Firsching, Anne Voß, Achim D. Gruber, Luca V. Hummel, Ivan Fernandez Munoz, Francesca Müller-Marquardt, Gerald Willimsky, Nooran S. Elleboudy, Jakob Trimpert, Günther Schönrich
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has highlighted the danger posed by human coronaviruses. Rapid emergence of immunoevasive variants and waning antivira
Externí odkaz:
https://doaj.org/article/c6aaf49ce07547e3a2fd4dc32b8a59b3
Autor:
Jakob Kreye, S. Momsen Reincke, Stefan Edelburg, Lara M. Jeworowski, Hans-Christian Kornau, Jakob Trimpert, Peter Hombach, Sophia Halbe, Volker Nölle, Martin Meyer, Stefanie Kattenbach, Elisa Sánchez-Sendin, Marie L. Schmidt, Tatjana Schwarz, Ruben Rose, Andi Krumbholz, Sophie Merz, Julia M. Adler, Kathrin Eschke, Azza Abdelgawad, Dietmar Schmitz, Leif E. Sander, Uwe Janssen, Victor M. Corman, Harald Prüss
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106323- (2023)
Summary: The recurrent emerging of novel viral variants of concern (VOCs) with evasion of preexisting antibody immunity upholds severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) case numbers and maintains a persistent demand for updated th
Externí odkaz:
https://doaj.org/article/f239808c0b29429ea48ba7fde057f1ba
Autor:
Iart Luca Shytaj, Mohamed Fares, Lara Gallucci, Bojana Lucic, Mahmoud M. Tolba, Liv Zimmermann, Julia M. Adler, Na Xing, Judith Bushe, Achim D. Gruber, Ina Ambiel, Ahmed Taha Ayoub, Mirko Cortese, Christopher J. Neufeldt, Bettina Stolp, Mohamed Hossam Sobhy, Moustafa Fathy, Min Zhao, Vibor Laketa, Ricardo Sobhie Diaz, Richard E. Sutton, Petr Chlanda, Steeve Boulant, Ralf Bartenschlager, Megan L. Stanifer, Oliver T. Fackler, Jakob Trimpert, Andrea Savarino, Marina Lusic
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Combinations of direct-acting antivirals are needed to minimize drug resistance mutations and stably suppress replication of RNA viruses. Currently, there are limited therapeutic options against the severe acute respiratory syndrome coronavi
Externí odkaz:
https://doaj.org/article/30bf4bc23be645f7a9bdfa7dd16e08e5
Autor:
Jakob Trimpert, Susanne Herwig, Julia Stein, Daria Vladimirova, Julia M. Adler, Azza Abdelgawad, Theresa C. Firsching, Tizia Thoma, Jalid Sehouli, Klaus Osterrieder, Achim D. Gruber, Birgit Sawitzki, Leif Erik Sander, Günter Cichon
Publikováno v:
Viruses, Vol 13, Iss 11, p 2290 (2021)
With the exception of inactivated vaccines, all SARS-CoV-2 vaccines currently used for clinical application focus on the spike envelope glycoprotein as a virus-specific antigen. Compared to other SARS-CoV-2 genes, mutations in the spike protein gene
Externí odkaz:
https://doaj.org/article/b30d56503a0141bb824f2651c751f2d7
Autor:
Beatrice Tolksdorf, Chuanxiong Nie, Daniela Niemeyer, Viola Röhrs, Johanna Berg, Daniel Lauster, Julia M. Adler, Rainer Haag, Jakob Trimpert, Benedikt Kaufer, Christian Drosten, Jens Kurreck
Publikováno v:
Viruses, Vol 13, Iss 10, p 2030 (2021)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected almost 200 million people worldwide and led to approximately 4 million deaths as of August 2021. Despite successful vaccine development, treatment options are limited. A promis
Externí odkaz:
https://doaj.org/article/0e97dddbff2f4fa1abe1e789fdf97ab6
Autor:
Raju Bej, Chuanxiong Nie, Kai Ludwig, Vahid Ahmadi, Jakob Trimpert, Julia M. Adler, Tatyana L Povolotsky, Katharina Achazi, Marten Kagelmacher, Ricardo Martin Vidal, Jens Dernedde, Benedikt B. Kaufer, Rainer Haag
Publikováno v:
Angewandte Chemie International Edition.