Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Julia M Rogers"'
Autor:
Li Pan, Madeleine E Lemieux, Tom Thomas, Julia M Rogers, Colin H Lipper, Winston Lee, Carl Johnson, Lynette M Sholl, Andrew P South, Jarrod A Marto, Guillaume O Adelmant, Stephen C Blacklow, Jon C Aster
Publikováno v:
eLife, Vol 9 (2020)
Notch signaling regulates squamous cell proliferation and differentiation and is frequently disrupted in squamous cell carcinomas, in which Notch is tumor suppressive. Here, we show that conditional activation of Notch in squamous cells activates a c
Externí odkaz:
https://doaj.org/article/ae52c805774448d4bf9d92c9ea73aab9
Autor:
Qinwen Liu, Pinar Onal, Rhea R Datta, Julia M Rogers, Urs Schmidt-Ott, Martha L Bulyk, Stephen Small, Joseph W Thornton
Publikováno v:
eLife, Vol 7 (2018)
The ancient mechanisms that caused developmental gene regulatory networks to diversify among distantly related taxa are not well understood. Here we use ancestral protein reconstruction, biochemical experiments, and developmental assays of transgenic
Externí odkaz:
https://doaj.org/article/cd4ba06be696424196a71f5fdaa8b314
Autor:
Kian Hong Kock, Patrick K. Kimes, Stephen S. Gisselbrecht, Sachi Inukai, Sabrina K. Phanor, James T. Anderson, Gayatri Ramakrishnan, Colin H. Lipper, Dongyuan Song, Jesse V. Kurland, Julia M. Rogers, Raehoon Jeong, Stephen C. Blacklow, Rafael A. Irizarry, Martha L. Bulyk
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Homeodomains (HDs) are the second largest class of DNA binding domains (DBDs) among eukaryotic sequence-specific transcription factors (TFs) and are the TF structural class with the largest number of disease-associated mutations in the Human
Externí odkaz:
https://doaj.org/article/fb03d33422b540199802faeaf082a440
Autor:
Alexandre P. Martin, Gary A. Bradshaw, Robyn J. Eisert, Emily D. Egan, Lena Tveriakhina, Julia M. Rogers, Andrew N. Dates, Gustavo Scanavachi, Jon C. Aster, Tom Kirchhausen, Marian Kalocsay, Stephen C. Blacklow
Notch signaling relies on ligand-induced proteolysis to liberate a nuclear effector that drives cell fate decisions. The location and timing of individual steps required for proteolysis and movement of Notch from membrane to nucleus, however, remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72eec61f8f702d2a049806bff5c2a4d9
https://doi.org/10.1101/2022.12.21.521435
https://doi.org/10.1101/2022.12.21.521435
Autor:
Ryan J. Lumpkin, Julia M. Rogers, Eric S. Fischer, Katherine A. Donovan, Ruili Cao, Vidyasiri Vemulapalli, Gregory D. Cuny, Soumya S. Ray, Stephen C. Blacklow, Matthew T. Henke, Munhyung Bae, Tom C. M. Seegar
Publikováno v:
Biochemistry
SHP2 is a protein tyrosine phosphatase that plays a critical role in the full activation of the Ras/MAPK pathway upon stimulation of receptor tyrosine kinases (RTKs), which are frequently amplified or mutationally activated in human cancer. In additi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c99921f529df55b873441f6821e2138
https://doi.org/10.1021/acs.biochem.1c00377
https://doi.org/10.1021/acs.biochem.1c00377
Autor:
John I. Murray, Shai Shaham, Karolina Mizeracka, Julia M. Rogers, Martha L. Bulyk, Jonathan D. Rumley, Maxwell G. Heiman
Publikováno v:
Development
During convergent differentiation, multiple developmental lineages produce a highly similar or identical cell type. However, few molecular players that drive convergent differentiation are known. Here, we show that the C. elegans Forkhead transcripti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d26340346e55a7f9c3af447bfb5a06
https://europepmc.org/articles/PMC8502252/
https://europepmc.org/articles/PMC8502252/
Publikováno v:
Protein Sci
Transcription activator‐like effector (TALE) proteins have been used extensively for targeted binding of fusion proteins to loci of interest in (epi)genome engineering. Such approaches typically utilize four canonical TALE repeat variable diresidue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32e926afc9ba17b6a85a894a25fa1e9
https://doi.org/10.1002/pro.3801
https://doi.org/10.1002/pro.3801
Autor:
Munhyung Bae, Tom C. M. Seegar, Ryan J. Lumpkin, Ruili Cao, Julia M. Rogers, Stephen C. Blacklow, Matthew T. Henke, Katherine A. Donovan, Vidyasiri Vemulapalli, Gregory D. Cuny, Eric S. Fischer
SHP2 is a protein tyrosine phosphatase that plays a critical role in the full activation of the Ras/MAPK pathway upon stimulation of receptor tyrosine kinases (RTKs), which are frequently amplified or mutationally activated in human cancer. In additi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98fe44701efe010ea5249a8d1bd44121
https://doi.org/10.1101/2021.06.02.446786
https://doi.org/10.1101/2021.06.02.446786
Autor:
Li Pan, Madeleine E. Lemieux, Carl Johnson, Tom Thomas, Colin H. Lipper, Julia M. Rogers, Winston Y. Lee, Jon C. Aster, Andrew P. South, Lynette M. Sholl, Stephen C. Blacklow, Guillaume Adelmant, Jarrod A. Marto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9b50f684947a7dc3296d0ac20e8da22
https://doi.org/10.7554/elife.58081.sa2
https://doi.org/10.7554/elife.58081.sa2
Autor:
Tom Thomas, Andrew P. South, Lynette M. Sholl, Carl Johnson, Colin H. Lipper, Guillaume Adelmant, Madeleine E. Lemieux, Julia M. Rogers, Li Pan, Winston Y. Lee, Stephen C. Blacklow, Jon C. Aster, Jarrod A. Marto
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Notch signaling regulates squamous cell proliferation and differentiation and is frequently disrupted in squamous cell carcinomas, in which Notch is tumor suppressive. Here, we show that conditional activation of Notch in squamous cells activates a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cf7f84ef3aeaf4b0027dbeb88667df
http://europepmc.org/articles/PMC7529455
http://europepmc.org/articles/PMC7529455