Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Julia M, Laufer"'
Autor:
Julia C. Gutjahr, Elisabeth Bayer, Xiaobing Yu, Julia M. Laufer, Jan P. Höpner, Suzana Tesanovic, Andrea Härzschel, Georg Auer, Tanja Rieß, Astrid Salmhofer, Eva Szenes, Theresa Haslauer, Valerie Durand-Onayli, Andrea Ramspacher, Sandra P. Pennisi, Marc Artinger, Nadja Zaborsky, Alexandre Chigaev, Fritz Aberger, Daniel Neureiter, Lisa Pleyer, Daniel F. Legler, Veronique Orian-Rousseau, Richard Greil, Tanja N. Hartmann
Publikováno v:
Haematologica, Vol 106, Iss 8 (2020)
Adhesive properties of leukemia cells shape the degree of organ infiltration and the extent of leukocytosis. CD44 and the integrin VLA-4, a CD49d/CD29 heterodimer, are important factors of progenitor cell adhesion in bone marrow (BM). Here, we report
Externí odkaz:
https://doaj.org/article/9bf54160724d40848f05cabcbde9c7ee
Autor:
Julia M. Laufer, Mark A. Hauser, Ilona Kindinger, Vladimir Purvanov, Andreas Pauli, Daniel F. Legler
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 995-1009.e6 (2019)
Summary: Chemokine-guided cell migration is pivotal for many immunological and developmental processes. How chemokine receptor signaling persists to guarantee sustained directional migration despite receptor desensitization and internalization remain
Externí odkaz:
https://doaj.org/article/ea564785a5f1495bbbce98a339b5567a
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
The chemokine receptor CCR7 guides T cells and dendritic cells to and within lymph nodes to launch the onset of adaptive immunity. Here, we demonstrate that CCR7 in addition acts as a potent co-stimulatory molecule in T cell activation. We found that
Externí odkaz:
https://doaj.org/article/a326b69f559947538e437434aa41741b
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
T cell migration from blood to, and within lymphoid organs and tissue, as well as, T cell activation rely on complex biochemical signaling events. But T cell migration and activation also take place in distinct mechanical environments and lead to dra
Externí odkaz:
https://doaj.org/article/9da17ff215694f79a7871bcd19523614
Autor:
Julia M. Laufer, Daniel F. Legler
Publikováno v:
Journal of Leukocyte Biology. 104:301-312
Chemokines and their receptors coordinate the positioning of leukocytes, and lymphocytes in particular, in space and time. Discrete lymphocyte subsets, depending on their activation and differentiation status, express various sets of chemokine recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04c095dce5f477ad10be5af22bc64ea
https://doi.org/10.1002/jlb.2mr1217-494r
https://doi.org/10.1002/jlb.2mr1217-494r
Autor:
Marc Artinger, Véronique Orian-Rousseau, Lisa Pleyer, Fritz Aberger, Suzana Tesanovic, Elisabeth Bayer, Daniel Neureiter, Andrea Härzschel, Valerie Durand-Onayli, Tanja Rieß, Jan Philip Höpner, Alexandre Chigaev, Georg Auer, Julia Christine Gutjahr, Nadja Zaborsky, Richard Greil, Daniel F. Legler, Julia M. Laufer, Sandra Pennisi, Astrid Salmhofer, Xiaobing Yu, Andrea Ramspacher, Tanja Nicole Hartmann, Theresa Haslauer, Eva Szenes
Publikováno v:
Haematologica, 106 (8), 2102-2113
Haematologica
Haematologica
Adhesive properties of leukemia cells shape the degree of organ infiltration and the extent of leukocytosis. CD44 and the integrin VLA-4, a CD49d/CD29 heterodimer, are important factors of progenitor cell adhesion in bone marrow (BM). Here, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7bde17c88e6e52bc9f73a02d5ff2aa8
https://publikationen.bibliothek.kit.edu/1000127084
https://publikationen.bibliothek.kit.edu/1000127084
Autor:
Julia M, Laufer, Mark A, Hauser, Ilona, Kindinger, Vladimir, Purvanov, Andreas, Pauli, Daniel F, Legler
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 995-1009.e6 (2019)
Summary: Chemokine-guided cell migration is pivotal for many immunological and developmental processes. How chemokine receptor signaling persists to guarantee sustained directional migration despite receptor desensitization and internalization remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::909079edfc0f6b91c57012c50b050d33
Autor:
Vladimir Purvanov, Christoph Matti, Barbara D. Jakobs, Julia M. Laufer, Edith Uetz-von Allmen, Daniel F. Legler, Marcus Thelen
Publikováno v:
Molecular Pharmacology. 91:331-338
Chemokine receptors are seven transmembrane-domain receptors belonging to class A of G-protein-coupled receptors (GPCRs). The receptors together with their chemokine ligands constitute the chemokine system, which is essential for directing cell migra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5b9ed66d52cb4018e3775a6580622a
https://doi.org/10.1124/mol.116.107151
https://doi.org/10.1124/mol.116.107151
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 32(9)
The ζ-associated protein of 70 kDa (ZAP70) is expressed in the aggressive form of B-cell chronic lymphocytic leukemia (CLL). Moreover, the integrin very late antigen (VLA)-1 is highly expressed on subtypes of CLL that are associated with high prolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e9211e879cab7ad6bbbab034f40747
https://pubmed.ncbi.nlm.nih.gov/29589978
https://pubmed.ncbi.nlm.nih.gov/29589978
Autor:
Sarah L. Vanes, Anne-Katrin Späte, Daniel F. Legler, Ilona Kindinger, Valentin Wittmann, Mark A. Hauser, Delia Bucher, Wolfgang A. Krueger, Julia M. Laufer
Publikováno v:
Journal of Leukocyte Biology
The homeostatic chemokines CCL19 and CCL21 and their common cognate chemokine receptor CCR7 orchestrate immune cell trafficking by eliciting distinct signaling pathways. Here, we demonstrate that human CCR7 is N-glycosylated on 2 specific residues in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf223fcf8e2dc18d817ea2b63faf7b67