Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Julia M, Brown"'
Publikováno v:
Microbiome, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Background Single amplified genomes (SAGs) and metagenome-assembled genomes (MAGs) are the predominant sources of information about the coding potential of uncultured microbial lineages, but their strengths and limitations remain poorly unde
Externí odkaz:
https://doaj.org/article/1bc2201442d3461d8c23b8f1eb61890d
Autor:
Jesudian Gnanaraj, William S Bolton, Peter R Culmer, Julia M Brown, Ibrahim Bundu, David G Jayne, Bonnie Cundill, Noel K Aruparayil, Julian Scott
Publikováno v:
BMJ Surgery, Interventions, & Health Technologies, Vol 6, Iss 1 (2024)
Objective The Global IDEAL Sub-Framework Study aimed to combine the intended effects of the 2009/2019 IDEAL (Idea, Development, Exploration, Assessment, Long-term study) Framework recommendations on evaluating surgical innovation with the vision outl
Externí odkaz:
https://doaj.org/article/a9c940dbc3054a36acf6db7200e9d5d3
Autor:
Giandomenico Bisaccia, MD, Peter Swoboda, John F. Younger, MD, MB, Neil Maredia, MD, Catherine J. Dickinson, MD, Julia M. Brown, MSc, BSc, Chiara Bucciarelli-Ducci, MD, PhD, Sven Plein, MD, PhD, John P Greenwood, MD, PhD
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss , Pp 100167- (2024)
Externí odkaz:
https://doaj.org/article/77bd0e1126724140b852b9ff9507586d
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Surgical interventions are complex. Key elements of this complexity are the surgeon and their learning curve. They pose methodological challenges in the design, analysis and interpretation of surgical RCTs. We identify, summarise,
Externí odkaz:
https://doaj.org/article/e6c7cad8167d4dfc9df453f9da32477e
Autor:
Kathryn M. Kauffman, William K. Chang, Julia M. Brown, Fatima A. Hussain, Joy Yang, Martin F. Polz, Libusha Kelly
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Understanding the interactions between bacteria and their viruses (phages) in natural communities is a major challenge. Here, the authors isolate and study large numbers of marine Vibrio bacteria and their phages, and find that lytic interactions are
Externí odkaz:
https://doaj.org/article/3cb1d1fcf9ee4a649cf2fb673d2b23b4
Autor:
Ameeta Retzer, Melanie Calvert, Khaled Ahmed, Thomas Keeley, Jo Armes, Julia M. Brown, Lynn Calman, Anna Gavin, Adam W. Glaser, Diana M. Greenfield, Anne Lanceley, Rachel M. Taylor, Galina Velikova, Michael Brundage, Fabio Efficace, Rebecca Mercieca‐Bebber, Madeleine T. King, Derek Kyte
Publikováno v:
Cancer Medicine, Vol 10, Iss 16, Pp 5475-5487 (2021)
Abstract Purpose Evidence suggests that the patient‐reported outcome (PRO) content of cancer trial protocols is frequently inadequate and non‐reporting of PRO findings is widespread. This qualitative study examined the factors influencing subopti
Externí odkaz:
https://doaj.org/article/bc075082c53c4442903d408c49f7cd91
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-16 (2021)
Abstract Background and purpose Multi-arm non-inferiority (MANI) trials, here defined as non-inferiority trials with multiple experimental treatment arms, can be useful in situations where several viable treatments exist for a disease area or for tes
Externí odkaz:
https://doaj.org/article/74f9d221d88f4fe3915b455cd5ccead0
Autor:
Dena R. Howard, Anna Hockaday, Julia M. Brown, Walter M. Gregory, Susan Todd, Tahla Munir, Jamie B. Oughton, Claire Dimbleby, Peter Hillmen
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background The FLAIR trial in chronic lymphocytic leukaemia has a randomised, controlled, open-label, confirmatory, platform design. FLAIR was successfully amended to include an emerging promising experimental therapy to expedite its assessm
Externí odkaz:
https://doaj.org/article/f5a4a538c4cd4e3c8cd38fb1ff778296
Autor:
Helen R Please, Jonathan H Vas Nunes, Rashida Patel, Gerd Pluschke, Mohamed Tholley, Marie-Therésè Ruf, William Bolton, Julian A Scott, Martin P Grobusch, Håkon A Bolkan, Julia M Brown, David G Jayne
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009862 (2021)
BackgroundChronic wounds pose a significant healthcare burden in low- and middle-income countries. Buruli ulcer (BU), caused by Mycobacterium ulcerans infection, causes wounds with high morbidity and financial burden. Although highly endemic in West
Externí odkaz:
https://doaj.org/article/28c49c63e3434e459f8121b2830dba0d
Autor:
Claudia Rutherford, Julia M. Brown, Isabelle Smith, Elizabeth McGinnis, Lyn Wilson, Rachael Gilberts, Sarah Brown, Susanne Coleman, Howard Collier, Jane Nixon
Publikováno v:
Health and Quality of Life Outcomes, Vol 16, Iss 1, Pp 1-11 (2018)
Abstract Introduction Pressure ulcer-specific patient-reported outcome (PRO) instruments should be used to inform patient care and provide a strong evidence base for interventions aimed at preventing pressure ulcers. The aim was to carry out a compre
Externí odkaz:
https://doaj.org/article/58445dae52bd4993b22ddd8846a0729b