Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Julia Liang"'
Autor:
Eleni Pitsillou, Julia Liang, Katherine Ververis, Kah Wai Lim, Andrew Hung, Tom C. Karagiannis
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
COVID-19 is an ongoing pandemic caused by the SARS-CoV-2 virus with important political, socio-economic, and public health consequences. Inhibiting replication represents an important antiviral approach, and in this context two viral proteases, the S
Externí odkaz:
https://doaj.org/article/f59f438c29274730b188467abd5c38ae
Autor:
Muhammad Shahid Javaid, Ana Antonic-Baker, Eleni Pitsillou, Julia Liang, Chris French, Andrew Hung, Terence J. O'Brien, Patrick Kwan, Tom C. Karagiannis, Alison Anderson
Publikováno v:
Journal of molecular graphicsmodelling. 112
Oxidative stress is one of the pathophysiological mechanisms implicated in drug-resistant epilepsy. Recurrent seizures and prolonged treatment with anti-seizure medicines (ASMs) can produce reactive oxygen species (ROS) resulting in neuronal cell dam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea3ec1f36cc49d4eb3b36582e6bf3b5c
https://pubmed.ncbi.nlm.nih.gov/35026665
https://pubmed.ncbi.nlm.nih.gov/35026665
Autor:
Tom C. Karagiannis, Eleni Pitsillou, Sarah M. Bresnehan, Andrew Hung, Julia Liang, Stevano J. Wijoyo, Evan A. Kagarakis
Publikováno v:
Molecular Biology Reports. 47:753-770
Major depressive disorder (MDD) is considered a serious public health issue that adversely impacts an individual's quality of life and contributes significantly to the global burden of disease. The clinical heterogeneity that exists among patients li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83cae7d5922e0763e231ce55a2750299
https://doi.org/10.1007/s11033-019-05129-3
https://doi.org/10.1007/s11033-019-05129-3
Conditional Machine Learning-Based Inverse Design Across Multiple Classes of Nanophotonic Structures
Autor:
Benjamin Pham, Yusaku Kawagoe, David Ho, Christopher Yeung, Ryan Tsai, Brian King, Mark W. Knight, Aaswath Raman, Julia Liang
Publikováno v:
Conference on Lasers and Electro-Optics.
We present a machine learning-based photonics design strategy centered on encoding image colors with material and structural data. Given input target spectra, our model can accurately determine the optimal metasurface class, materials, and structure.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f79e7a3cf3f6bc41d28d4420c9bc76c
https://doi.org/10.1364/cleo_qels.2021.aw3e.6
https://doi.org/10.1364/cleo_qels.2021.aw3e.6
Publikováno v:
Chemical Physics Letters
Graphical abstract
The SARS-CoV-2 papain-like protease (PLpro) is a suitable target for drug development, and its deubiquitinating and deISGylating activities have also been reported. In this study, molecular docking was used to investigate the
The SARS-CoV-2 papain-like protease (PLpro) is a suitable target for drug development, and its deubiquitinating and deISGylating activities have also been reported. In this study, molecular docking was used to investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf54a0513cfc26bfba2983689d77c89d
https://pubmed.ncbi.nlm.nih.gov/33716308
https://pubmed.ncbi.nlm.nih.gov/33716308
Publikováno v:
Life sciences. 265
Circadian rhythms are responsible for regulating a number of physiological processes. The central oscillator is located within the suprachiasmatic nucleus (SCN) of the hypothalamus and the SCN synchronises the circadian clocks that are found in our p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd3d591858aef7bcdbd7252852c82d7
https://pubmed.ncbi.nlm.nih.gov/33249097
https://pubmed.ncbi.nlm.nih.gov/33249097
Autor:
Christopher Yeung, Ju-Ming Tsai, Benjamin Pham, David Ho, Mark W. Knight, Julia Liang, Aaswath Raman, Brian King
Publikováno v:
Nanophotonics, Vol 10, Iss 3, Pp 1133-1143 (2021)
Complex nanophotonic structures hold the potential to deliver exquisitely tailored optical responses for a range of applications. Metal–insulator–metal (MIM) metasurfaces arranged in supercells, for instance, can be tailored by geometry and mater
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb67160f658ef9731e7163229565084
http://arxiv.org/abs/2008.00587
http://arxiv.org/abs/2008.00587
Autor:
Tom C. Karagiannis, Kevion K. Darmawan, Andrew Hung, Chris Karagiannis, Eleni Pitsillou, Ken Ng, Julia Liang
Publikováno v:
Computational Biology and Chemistry
Graphical abstract
Highlights • The SARS-CoV-2 main protease (Mpro) has an important role in the viral life cycle. • Inhibition of the active site or dimerization site of Mpro can mitigate activity. • Mapping reveals a reactive pocket in t
Highlights • The SARS-CoV-2 main protease (Mpro) has an important role in the viral life cycle. • Inhibition of the active site or dimerization site of Mpro can mitigate activity. • Mapping reveals a reactive pocket in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee56c339fe0731fdd58b386cb09b05c
https://pubmed.ncbi.nlm.nih.gov/32911432
https://pubmed.ncbi.nlm.nih.gov/32911432
Publikováno v:
Journal of molecular graphicsmodelling. 101
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to reduce pain, and function by targeting cyclooxygenase (COX) enzymes to inhibit the production of prostaglandins that facilitate inflammation. Since oleocanthal derived from Olea euro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf9202858b23f8fbcfe2bb4a92ce1b5
https://pubmed.ncbi.nlm.nih.gov/32920237
https://pubmed.ncbi.nlm.nih.gov/32920237
Publikováno v:
Journal of molecular graphicsmodelling. 101
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to reduce pain. These target cyclooxygenase (COX) enzymes which produce inflammatory mediators. Adverse effects associated with the use of traditional NSAIDs have led to a rise in the dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8087815272feb92b279ab16b4b53289b
https://pubmed.ncbi.nlm.nih.gov/32898836
https://pubmed.ncbi.nlm.nih.gov/32898836