Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Julia Leschik"'
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7339 (2021)
Newborn neurons in the adult hippocampus are regulated by many intrinsic and extrinsic cues. It is well accepted that elevated glucocorticoid levels lead to downregulation of adult neurogenesis, which this review discusses as one reason why psychiatr
Externí odkaz:
https://doaj.org/article/74a476bb5f4e446eae2724e63a0ba107
Publikováno v:
Stem Cell Reports, Vol 7, Iss 4, Pp 693-706 (2016)
Huntington's disease (HD) is characterized by fatal motoric failures induced by loss of striatal medium spiny neurons. Neuronal cell death has been linked to impaired expression and axonal transport of the neurotrophin BDNF (brain-derived neurotrophi
Externí odkaz:
https://doaj.org/article/536ec862493b4b86b3ac2e34c3552951
Autor:
Bianca Seifert, Robert Eckenstaler, Raik Rönicke, Julia Leschik, Beat Lutz, Klaus Reymann, Volkmar Lessmann, Tanja Brigadski
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
The neurotrophin brain derived neurotrophic factor (BDNF) is an important growth factor in the CNS. Deficits in transport of this secretory protein could underlie neurodegenerative diseases. Investigation of disease-related changes in BDNF transport
Externí odkaz:
https://doaj.org/article/292bd4fa5e2e43939f05e7e86f430b5f
Autor:
Julia Leschik, Antonietta Gentile, Cigdem Cicek, Sophie Péron, Margaryta Tevosian, Annika Beer, Konstantin Radyushkin, Anna Bludau, Karl Ebner, Inga Neumann, Nicolas Singewald, Benedikt Berninger, Volkmar Lessmann, Beat Lutz
Publikováno v:
Leschik, J, Gentile, A, Cicek, C, Peron, S, Tevosian, M, Beer, A, Radyushkin, K, Bludau, A, Ebner, K, Neumann, I, Singewald, N, Berninger, B, Lessmann, V & Lutz, B 2022, ' Brain-derived neurotrophic factor expression in serotonergic neurons improves stress resilience and promotes adult hippocampal neurogenesis ', Progress in Neurobiology, vol. 217, 102333 . https://doi.org/10.1016/j.pneurobio.2022.102333
The neurotrophin brain-derived neurotrophic factor (BDNF) stimulates adult neurogenesis, but also influences structural plasticity and function of serotonergic neurons. Both, BDNF/TrkB signaling and the serotonergic system modulate behavioral respons
Autor:
Robert Eckenstaler, Elke Edelmann, Thomas Endres, Tanja Brigadski, Klaus-Dieter Fischer, Beat Lutz, Karin Richter, Werner Zuschratter, Oliver Kobler, Julia Leschik, Thomas Munsch, Volkmar Lessmann
Publikováno v:
Molecular Neurobiology. 56:6833-6855
Brain-derived neurotrophic factor (BDNF) is a secreted messenger molecule that is crucial for neuronal function and induction of synaptic plasticity. Although altered availability of BDNF underlies many neurological deficits and neurodegenerative dis
Autor:
Anne-Claire Guénantin, Erwan Watrin, Michel Pucéat, Gisèle Bonne, Nicolas Vignier, Imen Jebeniani, Julia Leschik
Publikováno v:
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2021, 131 (1), ⟨10.1172/JCI136488⟩
Journal of Clinical Investigation, 2021, 131 (1), ⟨10.1172/JCI136488⟩
J Clin Invest
Journal of Clinical Investigation, American Society for Clinical Investigation, 2021, 131 (1), ⟨10.1172/JCI136488⟩
Journal of Clinical Investigation, 2021, 131 (1), ⟨10.1172/JCI136488⟩
J Clin Invest
International audience; LMNA mutations in patients are responsible for a dilated cardiomyopathy. Molecular mechanisms underlying the origin and development of the pathology are unknown. Herein, using mouse pluripotent embryonic stem cells (ESCs) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd361746c9539c0c77efd0715d8eac0
https://hal.archives-ouvertes.fr/hal-03134235/document
https://hal.archives-ouvertes.fr/hal-03134235/document
Publikováno v:
International journal of molecular sciences, 22(14):7339
International Journal of Molecular Sciences, Vol 22, Iss 7339, p 7339 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 7339, p 7339 (2021)
International Journal of Molecular Sciences
Newborn neurons in the adult hippocampus are regulated by many intrinsic and extrinsic cues. It is well accepted that elevated glucocorticoid levels lead to downregulation of adult neurogenesis, which this review discusses as one reason why psychiatr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c02af254b530e637ddd180c186f80d
https://repository.publisso.de/resource/frl:6430874
https://repository.publisso.de/resource/frl:6430874
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 7, Iss 4, Pp 693-706 (2016)
Stem Cell Reports, Vol 7, Iss 4, Pp 693-706 (2016)
Summary Huntington's disease (HD) is characterized by fatal motoric failures induced by loss of striatal medium spiny neurons. Neuronal cell death has been linked to impaired expression and axonal transport of the neurotrophin BDNF (brain-derived neu
Publikováno v:
Stem Cells and Development. 24:384-392
Human embryonic stem (HUES) cells are derived from early individual embryos with unique genetic printing. However, how their epigenetic status might affect their potential to differentiate toward specific lineages remains a puzzling question. Using c
Publikováno v:
Journal of visualized experiments : JoVE
Journal of visualized experiments : JoVE, JoVE, 2016, pp. e53874. ⟨10.3791/53874⟩
Journal of visualized experiments : JoVE, 2016, 112, pp. e53874. ⟨10.3791/53874⟩
Journal of visualized experiments : JoVE, JoVE, 2016, pp. e53874. ⟨10.3791/53874⟩
Journal of visualized experiments : JoVE, 2016, 112, pp. e53874. ⟨10.3791/53874⟩
International audience; Specific gene transcription is a key biological process that underlies cell fate decision during embryonic development. The biological process is mediated by transcription factors which bind genomic regulatory regions includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657b1f7ea153c02ad485e06235d314fc
https://www.hal.inserm.fr/inserm-01334550/file/jove-protocol-53874-epigenetic-regulation-cardiac-differentiation-embryonic-stem-cells.pdf
https://www.hal.inserm.fr/inserm-01334550/file/jove-protocol-53874-epigenetic-regulation-cardiac-differentiation-embryonic-stem-cells.pdf