Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Julia Lehtinen"'
Autor:
Julia Lehtinen, Mari Raki, Kim A Bergström, Päivi Uutela, Katariina Lehtinen, Annukka Hiltunen, Jere Pikkarainen, Huamin Liang, Sari Pitkänen, Ann-Marie Määttä, Raimo A Ketola, Marjo Yliperttula, Thomas Wirth, Arto Urtti
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41410 (2012)
BACKGROUND: Epidermal growth factor receptor (EGFR) is overexpressed in many solid tumor types, such as ovarian carcinoma. Immunoliposome based drug targeting has shown promising results in drug delivery to the tumors. However, the ratio of tumor-to-
Externí odkaz:
https://doaj.org/article/503018bf1f2148a89d56c2f7c458ea89
Autor:
Sarah J. Butcher, Vladimir Aseyev, Arto Urtti, Heikki Tenhu, Anu M. Alhoranta, Julia Lehtinen
Publikováno v:
Biomacromolecules. 12:3213-3222
A series of amphiphilic star and linear block copolymers were synthesized using ATRP. The core consisted of either polystyrene (PS) or poly(n-butyl acrylate) (PBuA), having different glass-transition (T(g)) values. These polymers were used as macroin
Publikováno v:
Journal of Controlled Release. 131:145-149
Cationic polymers are efficient gene delivery vectors in in vitro conditions, but these carriers can fail in vivo due to interactions with extracellular polyanions, i.e. glycosaminoglycans (GAG). The aim of this study was to develop a stable gene del
Autor:
Markus Linder, Olli Ikkala, Géza R. Szilvay, Arto Urtti, David K. Smith, Julia Lehtinen, Mauri A. Kostiainen
Publikováno v:
Kostiainen, M A, Szilvay, G, Lehtinen, J, Smith, D K, Linder, M, Urtti, A & Ikkala, O 2007, ' Precisely defined protein-polymer conjugates: construction of synthetic DNA binding domains on proteins by using multivalent dendrons ', ACS Nano, vol. 1, no. 2, pp. 103-113 . https://doi.org/10.1021/nn700053y
Nature has evolved proteins and enzymes to carry out a wide range of sophisticated tasks. Proteins modified with functional polymers possess many desirable physical and chemical properties and have applications in nanobiotechnology. Here we describe
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 50(3-4)
In this study, we present a novel in vitro approach that utilizes two surface-sensitive and label-free techniques, i.e. surface plasmon resonance (SPR) and quartz crystal microbalance (QCM), to study the interfacial events during liposome–target su
Autor:
Tomasz Róg, Julia Lehtinen, Satu Hakola, Marjo Yliperttula, Arto Urtti, Aniket Magarkar, Michał Stepniewski, Alex Bunker, Mathias Bergman
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 46(3)
Drug nanocarriers are often derivatized with targeting moieties to achieve site specific delivery, however, the results from this approach have, as yet, not reached expectations. We have tested a new phage display based targeting moiety, the activate
Autor:
Ann-Marie Määttä, Raimo A. Ketola, Päivi Uutela, Arto Urtti, Marjo Yliperttula, Huamin Liang, Kim Bergström, Mari Raki, Julia Lehtinen, Jere Pikkarainen, Annukka Hiltunen, Sari Pitkänen, Katariina Lehtinen, Thomas Wirth
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41410 (2012)
PLoS ONE
PLoS ONE
BACKGROUND: Epidermal growth factor receptor (EGFR) is overexpressed in many solid tumor types, such as ovarian carcinoma. Immunoliposome based drug targeting has shown promising results in drug delivery to the tumors. However, the ratio of tumor-to-