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of 5
pro vyhledávání: '"Julia L.M. Dunn"'
Three Distinct Transcriptional Profiles of Monocytes Associate with Disease Activity in SSc Patients
Autor:
Hadijat-Kubura M. Makinde, Julia L.M. Dunn, Gaurav Gadhvi, Mary Carns, Kathleen Aren, Anh H. Chung, Lutfiyya N. Muhammad, Jing Song, Carla M. Cuda, Salina Dominguez, John E. Pandolfino, Jane E. Dematte D’Amico, G. Scott Budinger, Shervin Assassi, Tracy Frech, Dinesh Khanna, Alex Shaeffer, Harris Perlman, Monique Hinchcliff, Deborah R. Winter
Background/PurposePatients with systemic sclerosis (SSc) display a complex clinical phenotype. There are numerous studies that relate transcriptional signatures from PBMC or whole skin of SSc patients to disease activity. However, analyses of whole t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29c8b1ffcaf3a1afc045d525e2094e6d
https://doi.org/10.1101/2022.01.29.477568
https://doi.org/10.1101/2022.01.29.477568
Autor:
Julia L.M. Dunn, Matthew C. Wolfgang, Bruce A. Cairns, Lindsey I. Glenn, Danté N. Duncan, Robert Maile, Laurel B. Kartchner, Cindy J. Gode
Publikováno v:
Burns
Objective Burn injury induces an acute hyperactive immune response followed by a chronic immune dysregulation that leaves those afflicted susceptible to multiple secondary infections. Many murine models are able to recapitulate the acute immune respo
Autor:
Wesley H. Stepp, Madison M. Malfitano, Lindsey I. Glenn, Robert Maile, Bruce A. Cairns, Laurel B. Kartchner, Julia L.M. Dunn, Samuel W. Jones, Claire M. Doerschuk
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 314:L822-L834
Smoke inhalation associated with structural fires, wildfires, or explosions leads to lung injury, for which innovative and clinically relevant animal models are needed to develop effective therapeutics. We have previously reported that damage-associa
Autor:
Rebecca A. Hunter, Marci R. Sessions, Anthony R. Richardson, Bruce A. Cairns, Mark H. Schoenfisch, Lance R. Thurlow, Karli Gast, Laurel B. Kartchner, Julia L.M. Dunn, Robert Maile
Publikováno v:
Journal of Leukocyte Biology. 103:909-918
Bacterial pneumonia is a leading cause of death late after burn injury due to the severe immune dysfunction that follows this traumatic injury. The Mechanistic/Mammalian Target of Rapamycin (mTOR) pathway drives many effector functions of innate immu
Autor:
Bruce A. Cairns, Rebecca A. Hunter, Julia L.M. Dunn, Mark H. Schoenfisch, Robert Maile, Karli Gast
Publikováno v:
Burns. 42:1522-1527
Purpose Burn is associated with severe immune dysfunction, including an anti-inflammatory state that occurs late after burn. While increased nitric oxide (NO) production is associated with severe infection and sepsis, the effect of burn trauma on the