Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Julia L. Troy"'
Autor:
Mai Ots, Barry M. Brenner, Kang-Wook Lee, Julia L. Troy, Shinichiro Kato, Harald S. Mackenzie, Farzad Ziai, Valerie A. Luyckx
Publikováno v:
Kidney International. 56(3):1037-1048
Renin-angiotensin blockade lowers MCP-1 expression in diabetic rats. Background Glomerular macrophage accumulation in diabetes implicates monocyte recruitment mechanisms in the pathogenesis of diabetic nephropathy. To test the hypothesis that overexp
Publikováno v:
Journal of the American Society of Nephrology. 9:224-230
Angiotensin-converting enzyme inhibitors (ACEI) and angiotensin II receptor antagonists (AT1RA) slow the rate of progression of experimental renal disease. Although the end result of both classes of drugs is to block the renin-angiotensin system (RAS
Publikováno v:
Kidney International. 46:414-420
Effects of natriuretic peptide receptor inhibition on remnant kidney function in rats. To identify the contribution of natriuretic peptide (NP) activity to the adaptative increases in glomerular filtration rate (GFR), effective renal plasma flow rate
Publikováno v:
Journal of the American Society of Nephrology. 4:1564-1570
Previous studies from this laboratory implicated atrial natriuretic peptide (ANP) as a possible mediator of glomerular hyperfiltration in diabetic rats. In this study, the potential of HS-142-1 (HS), a novel polysaccharide compound with ANP receptor
Publikováno v:
Journal of the American Society of Nephrology. 3:214-228
Diffusion studies in vitro indicate that Ficoll behaves more like an ideal spherical molecule than does dextran, suggesting that Ficoll would be a better probe of glomerular pore size than the commonly used dextran. To examine the differences between
Publikováno v:
Journal of the American Society of Nephrology. 2:1072-1077
Endogenous nitric oxide is an important modulator of vascular smooth muscle tone. The role of nitric oxide in the vascular adaptation to systemic hypertension was examined by using N omega-monomethyl-L-arginine (L-NMMA; 110 micrograms/kg/min), a comp
Autor:
Helen M. Lafferty, Julia L. Troy, Helmut G. Rennke, Diego L. Garcia, Sharon Anderson, Barry M. Brenner
Publikováno v:
Journal of the American Society of Nephrology. 1:1180-1185
To explore the role of systemic hematocrit in the vascular adaptations which characterize desoxycorticosterone-salt hypertension, studies were performed in three groups of rats with uninephrectomy, desoxycorticosterone administration, and 1% saline i
Publikováno v:
Journal of the American Society of Nephrology. 1:1095-1108
Female Munich-Wistar rats received hexadimethrine (HDM) i.v. until the onset of proteinuria (PEAK)--a period of not more than 30 min. There were four experimental groups: C (control), H (HDM only), HH (HDM and heparin), and HHD (identical to HH but w
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 19(2)
Background. To test the hypothesis that nephron mass is an independent determinant of arterial pressure, the effects of augmenting renal mass by isograft transplantation were studied in the model of secondary hypertension. Methods. The effects of iso
Autor:
Olga V. Sakharova, Julia L. Troy, Waichi Wong, Vesselin D. Nenov, Maarten W. Taal, Barry M. Brenner, Jeong Hoon Choi, Sharad R Satyal
Publikováno v:
Journal of the American Society of Nephrology : JASN. 12(10)
The renoprotective efficacy of the vasopeptidase inhibitor omapatrilat (OMA) was compared with that of enalapril (ENA) in male Munich-Wistar rats subjected to 5/6 nephrectomy. ENA and OMA administered beginning on day 2 after surgery were equally eff