Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Julia Korell"'
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 6, Pp 758-769 (2023)
Abstract BI 730357 is investigated as an oral treatment of plaque psoriasis. We analyzed the impact of three dosage regimens on the Psoriasis Area and Severity Index (PASI) response with modeling based on phase I and II data from 109 healthy subjects
Externí odkaz:
https://doaj.org/article/9f3709a3d792455c8294af56375c3e83
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 2, Pp 87-95 (2020)
We describe a parametric time‐to‐event model for idiopathic pulmonary fibrosis (IPF) exacerbations and identify predictors of exacerbation risk using data obtained for the tyrosine‐kinase inhibitor nintedanib in two phase III studies (INPULSIS
Externí odkaz:
https://doaj.org/article/dc0a8deb55fd4386b42f8aeaef39bd7a
Publikováno v:
European Journal of Clinical Pharmacology. 74:593-599
Schizophrenia is a common disease which is commonly managed using antipsychotic medications (APS). Inadequate response and lack of adherence often prevent optimal therapeutic effectiveness. Monitoring APS concentrations can be useful to help improve
Publikováno v:
European Journal of Pharmaceutical Sciences. 109:S154-S160
Respiratory syncytial virus (RSV) causes acute lower respiratory tract infections, and is a major cause of hospital admissions and death in young children. Limited treatments currently exist that can prevent or minimise exacerbation of the disease. T
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. 6:589-595
Schizophrenia is a common disease managed by a range of interventions, with the primary treatment being antipsychotic medications (APS). Inadequate response, lack of adherence, and/or adverse events often prevent optimal therapeutic effects or therap
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 2, Pp 87-95 (2020)
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 2, Pp 87-95 (2020)
We describe a parametric time‐to‐event model for idiopathic pulmonary fibrosis (IPF) exacerbations and identify predictors of exacerbation risk using data obtained for the tyrosine‐kinase inhibitor nintedanib in two phase III studies (INPULSIS
Publikováno v:
60. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V..
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. 6:573-575
Schizophrenia is a common disease, characterized by progressive functional decline exacerbated by psychotic relapses that often result from a lack of full adherence to antipsychotic (APS) medication. Although atypical APS medications do not have clea
Publikováno v:
Revue des Maladies Respiratoires. 36:A135-A136
Introduction La FPI est une pneumopathie parenchymateuse chronique, progressive d’issue fatale. L’exploration des facteurs predictifs de mortalite dans la FPI est importante sur le plan clinique et pour le developpement de medicaments. La FDA a r
Autor:
Mei Zhang, Lisa K. Stamp, Jill Drake, Stephen B. Duffull, Judith M. Dalrymple, Murray L. Barclay, Julia Korell
Publikováno v:
British Journal of Clinical Pharmacology. 77:493-497
AimTo assess the similarities in intracellular pharmacokinetics (PK) of methotrexate (MTX) in red blood cells (RBCs) and other cell lines. MethodsThree previously published PK models for intracellu ...