Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Julia Kodysh"'
Autor:
Christof C. Smith, Kelly S. Olsen, Kaylee M. Gentry, Maria Sambade, Wolfgang Beck, Jason Garness, Sarah Entwistle, Caryn Willis, Steven Vensko, Allison Woods, Misha Fini, Brandon Carpenter, Eric Routh, Julia Kodysh, Timothy O’Donnell, Carsten Haber, Kirsten Heiss, Volker Stadler, Erik Garrison, Adam M. Sandor, Jenny P. Y. Ting, Jared Weiss, Krzysztof Krajewski, Oliver C. Grant, Robert J. Woods, Mark Heise, Benjamin G. Vincent, Alex Rubinsteyn
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-23 (2021)
Abstract Background Early in the pandemic, we designed a SARS-CoV-2 peptide vaccine containing epitope regions optimized for concurrent B cell, CD4+ T cell, and CD8+ T cell stimulation. The rationale for this design was to drive both humoral and cell
Externí odkaz:
https://doaj.org/article/1bd99e7646cd4b7097c6d90976a022a0
Autor:
Dimple Chakravarty, Parita Ratnani, Li Huang, Zachary Dovey, Stanislaw Sobotka, Roy Berryhill, Harri Merisaari, Majd Al Shaarani, Richa Rai, Ivan Jambor, Kamlesh K. Yadav, Sandeep Mittan, Sneha Parekh, Julia Kodysh, Vinayak Wagaskar, Rachel Brody, Carlos Cordon-Cardo, Dmitry Rykunov, Boris Reva, Elai Davicioni, Peter Wiklund, Nina Bhardwaj, Sujit S. Nair, Ashutosh K. Tewari
Publikováno v:
Cancers, Vol 14, Iss 11, p 2734 (2022)
The impact of pelvic inflammation on prostate cancer (PCa) biology and aggressive phenotype has never been studied. Our study objective was to evaluate the role of pelvic inflammation on PCa aggressiveness and its association with clinical outcomes i
Externí odkaz:
https://doaj.org/article/9196c21dc86a4948a1d3cf41c5da1359
Autor:
Benjamin Vincent, Timothy O’Donnell, Maria Sambade, Julia Kodysh, Steven Vensko, Wolfgang Beck, Christof Smith, Sarah Entwistle, Caryn Willis, Jason Garness, Eric Routh, Kelly Olsen, Brandon Carpenter, Kaylee Gentry, Maria Fadri, Misha Fini, Amber Washington, Carsten Haber, Kirsten Heiss, Volker Stadler, Erik Garrison, Oliver Grant, Robert Woods, Mark Heise, Alexander Rubinsteyn
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/9975b5795bbd45349adb1107b50c0243
Autor:
Nina Bhardwaj, Marshall Posner, Philip Friedlander, John Mandeli, Sacha Gnjatic, Eric Schadt, Samir Parekh, Julia Kodysh, Alex Rubinsteyn, John Finnigan, Ana Blazquez, Mansi Saxena, Marcia Meseck, Daniela Delbeau, Matthew Galsky, Deborah Doroshow, Brett Miles, Krysztof Misiukiewicz, Hanna Irie, Amy Tiersten, Andrea Wolf, Jeffrey Hammerbacher, Michael Donovan, Rachel Brody
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/2fdb09ee544e42f79751e40542a845ff
Autor:
Monica M. Olcina, Nikolas G. Balanis, Ryan K. Kim, B. Arman Aksoy, Julia Kodysh, Michael J. Thompson, Jeff Hammerbacher, Thomas G. Graeber, Amato J. Giaccia
Publikováno v:
Cell Reports, Vol 25, Iss 13, Pp 3721-3732.e6 (2018)
Summary: Complement-mediated cytotoxicity may act as a selective pressure for tumor overexpression of complement regulators. We hypothesize that the same selective pressure could lead to complement alterations at the genetic level. We find that, when
Externí odkaz:
https://doaj.org/article/43f706b039384f6aa667af346e276ebc
Autor:
Alex Rubinsteyn, Julia Kodysh, Isaac Hodes, Sebastien Mondet, Bulent Arman Aksoy, John P. Finnigan, Nina Bhardwaj, Jeffrey Hammerbacher
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
This paper describes the sequencing protocol and computational pipeline for the PGV-001 personalized vaccine trial. PGV-001 is a therapeutic peptide vaccine targeting neoantigens identified from patient tumor samples. Peptides are selected by a compu
Externí odkaz:
https://doaj.org/article/5976529a96fd4d6c9419a82fea91d16e
Autor:
Mansi Saxena, Thomas Marron, Julia Kodysh, Alex Rubinsteyn, John Finnigan, Ana Blasquez, Marcia Meseck, Tim O'Donnell, Daniela Delbeau, Mathew Galsky, Deborah Doroshow, Brett Miles, Krzysztof Misiukiewicz, Hanna Irie, Amy Tiersten, Samir Parekh, Marshall Posner, Andrea Wolf, John Mandeli, Rachel Brody, Sacha Gnjatic, Eric Schadt, Philip Friedlander, Nina Bhardwaj
Publikováno v:
Cancer Research. 83:CT270-CT270
Introduction: Immunotherapies such as checkpoint blockade, have demonstrated remarkable clinical efficacy yet a large percentage of patients do not respond, potentially due to a paucity of pre-existing immune priming against neoantigens. We developed
Autor:
O Timothy, Rachel Brody, Nina Bhardwaj, Cansu Cimen Bozkus, Adilia Hormigo, John Mandeli, Mansi Saxena, Marcia Meseck, Alex Rubinsteyn, Tin Htwe Thin, Julia Kodysh
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Ryan K. Kim, Amato J. Giaccia, Monica M. Olcina, Jeff Hammerbacher, Julia Kodysh, Michael Thompson, Nikolas G. Balanis, Thomas G. Graeber, B. Arman Aksoy
Publikováno v:
Cell Reports, Vol 25, Iss 13, Pp 3721-3732.e6 (2018)
Cell reports
Cell reports
Complement-mediated cytotoxicity may act as a selective pressure for tumor overexpression of complement regulators. We hypothesize that the same selective pressure could lead to complement alterations at the genetic level. We find that, when analyzed
Autor:
Philip Friedlander, Rachel Brody, Krysztof Misiukiewicz, Marcia Meseck, Mansi Saxena, Andrea S. Wolf, Timothy O'Donnell, Brett A. Miles, Eric E. Schadt, Julia Kodysh, Alex Rubinsteyn, Nina Bhardwaj, Ana Belen Blazquez, Sacha Gnjatic, Matthew D. Galsky, Michael J. Donovan, John P. Finnigan, Daniela Delbeau, Marshall R. Posner, Thomas U. Marron, Hanna Irie, John Mandeli, Samir Parekh, Amy Tiersten, Deborah B. Doroshow, Jeff Hammerbacher
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background The efficacy of T cell directed immunotherapies relies on adequate priming of T cells to tumor-specific neoantigens, which some studies have augmented with synthetic neoantigen vaccines. This is the first report of a personalized genomic v