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pro vyhledávání: '"Julia Koch-Heier"'
Autor:
Julia Koch-Heier, Annette B. Vogel, Yvonne Füll, Marina Ebensperger, Annika Schönsiegel, Raphael S. Zinser, Oliver Planz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Regulatory T cells (Tregs) play a crucial and complex role in balancing the immune response to viral infection. Primarily, they serve to regulate the immune response by limiting the expression of proinflammatory cytokines, reducing inflammation in in
Externí odkaz:
https://doaj.org/article/2a1c5d66cd4c42598f7e351f339bb757
Autor:
Helen Hoffmann, Marina Ebensperger, Annika Schönsiegel, Hazem Hamza, Julia Koch-Heier, André Schreiber, Stephan Ludwig, Michael Schindler, Oliver Planz
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
The recent COVID-19 pandemic again highlighted the urgent need for broad-spectrum antivirals, both for therapeutic use in acute viral infection and for pandemic preparedness in general. The targeting of host cell factors hijacked by viruses during th
Externí odkaz:
https://doaj.org/article/ee0f3717d31a4caaa2a67216398937c2
Autor:
Lara M. Schüssele, Julia Koch-Heier, Julian Volk, Markus W. Löffler, Katharina Hoffmann, Regina M. Bruyns, Oliver Planz
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The Raf/MEK/ERK signaling pathway plays a key role in regulating cellular proliferation, differentiation, apoptosis, cytokine production, and immune responses. However, it is also involved in diseases such as cancer, and numerous viruses rely on an a
Externí odkaz:
https://doaj.org/article/570a196fc06649cd97cda4740a096598
Autor:
Julia Koch-Heier, Annika Schönsiegel, Lara Maria Waidele, Julian Volk, Yvonne Füll, Christian Wallasch, Sebastian Canisius, Michael Burnet, Oliver Planz
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The mitogen-activated protein kinase (MEK) inhibitor zapnometinib is in development to treat acute viral infections like COVID-19 and influenza. While the antiviral efficacy of zapnometinib is well documented, further data on target engagement/pharma
Externí odkaz:
https://doaj.org/article/e3392661b71f4f1faa046b7781c6c23e
Publikováno v:
Microorganisms, Vol 9, Iss 3, p 521 (2021)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic effects daily dental work. Therefore, infection control measures are necessary to prevent infection of dental personnel during dental treatments. The use of a preprocedural mou
Externí odkaz:
https://doaj.org/article/6490ba631f174a158d679ec6ad792e5d
Autor:
Gerhard Müller, Martin Quernheim, Stephan Ludwig, Christin Müller, Martin Laure, André Schreiber, Stephan Pleschka, Hazem Hamza, Oliver Planz, Julia Koch-Heier
Publikováno v:
Antiviral research. 178
Antiviral therapies against influenza are required, especially for high-risk patients, severe influenza and in case of highly pathogenic influenza virus (IV) strains. However, currently, licensed drugs that target the virus directly are not very effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1567815d51590f029f4fd14fad4b05e
https://pubmed.ncbi.nlm.nih.gov/32304723
https://pubmed.ncbi.nlm.nih.gov/32304723