Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Julia Kallenbach"'
Autor:
Julia Kallenbach, Mahdi Rasa, Mehdi Heidari Horestani, Golnaz Atri Roozbahani, Katrin Schindler, Aria Baniahmad
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-21 (2024)
Abstract Background The androgen receptor (AR), a ligand-dependent transcription factor, plays a key role in regulating prostate cancer (PCa) growth. The novel bipolar androgen therapy (BAT) uses supraphysiological androgen levels (SAL) that suppress
Externí odkaz:
https://doaj.org/article/f3afaeb5762d4e9cacefdad6449f3044
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Background Prostate cancer (PCa) is an age-related malignancy in men with a high incidence rate. PCa treatments face many obstacles due to cancer cell resistance and many bypassing mechanisms to escape therapy. According to the intricacy of
Externí odkaz:
https://doaj.org/article/0258da3f7dc64036b7dd0518af5e2cc3
Autor:
Mohammad Taheri, Soudeh Ghafouri-Fard, Sajad Najafi, Julia Kallenbach, Elmira Keramatfar, Golnaz Atri Roozbahani, Mehdi Heidari Horestani, Bashdar Mahmud Hussen, Aria Baniahmad
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Naturally, in somatic cells chromosome ends (telomeres) shorten during each cell division. This process ensures to limit proliferation of somatic cells to avoid malignant proliferation; however, it leads to proliferative senescence. Telomera
Externí odkaz:
https://doaj.org/article/75a987fe67ab41da9f2778a403b42226
Autor:
Tim Schomann, Kimia Mirzakhani, Julia Kallenbach, Jing Lu, Seyed Mohammad Mahdi Rasa, Francesco Neri, Aria Baniahmad
Publikováno v:
Biomolecules, Vol 12, Iss 8, p 1048 (2022)
The bipolar androgen therapy (BAT) includes the treatment of prostate cancer (PCa) patients with supraphysiological androgen level (SAL). Interestingly, SAL induces cell senescence in PCa cell lines as well as ex vivo in tumor samples of patients. Th
Externí odkaz:
https://doaj.org/article/db81f71d360a48fa984985a502a6768b
Autor:
Mohammad Taheri, Tayyebeh Khoshbakht, Elena Jamali, Julia Kallenbach, Soudeh Ghafouri-Fard, Aria Baniahmad
Publikováno v:
Cells, Vol 10, Iss 11, p 3198 (2021)
The androgen receptor (AR) is a member of the nuclear receptor superfamily and has three functional domains, namely the N-terminal, DNA binding, and C-terminal domain. The N-terminal domain harbors potent transactivation functions, whereas the C-term
Externí odkaz:
https://doaj.org/article/4291a0fcb65a4b378fa033456c72936c
Autor:
Anna Melekhova, Mirjam Leeder, Thanakorn Pungsrinont, Tim Schmäche, Julia Kallenbach, Marzieh Ehsani, Kimia Mirzakhani, Seyed Mohammad Mahdi Rasa, Francesco Neri, Aria Baniahmad
Publikováno v:
Biomolecules, Vol 11, Iss 8, p 1152 (2021)
Inhibitor of growth 3 (ING3) is one of five members of the ING tumour suppressor family, characterized by a highly conserved plant homeodomain (PHD) as a reader of the histone mark H3K4me3. ING3 was reported to act as a tumour suppressor in many diff
Externí odkaz:
https://doaj.org/article/8c58cf88a46f4fe7add927b0f5e7697b
Autor:
Kimia Mirzakhani, Julia Kallenbach, Seyed Mohammad Mahdi Rasa, Federico Ribaudo, Martin Ungelenk, Marzieh Ehsani, Wenrong Gong, Nikolaus Gassler, Mirjam Leeder, Marc-Oliver Grimm, Francesco Neri, Aria Baniahmad
Publikováno v:
Oncogene. 41:1071-1077
Autor:
Marzieh Ehsani, Aria Baniahmad, Martin Ungelenk, Wenrong Gong, Julia Kallenbach, Federico Ribaudo, Nikolaus Gassler, Francesco Neri, Seyed Mohammad Mahdi Rasa, Marc-Oliver Grimm, Kimia Mirzakhani, Mirjam Leeder
The bipolar androgen therapy (BAT) to treat prostate cancer (PCa) includes cycles of supraphysiological androgen levels (SAL) under androgen-deprivation therapy (ADT). We showed previously that SAL induces cellular senescence in androgen-sensitive PC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7470c5b1b352bfdd787831ce9244870
http://hdl.handle.net/2318/1834367
http://hdl.handle.net/2318/1834367
Autor:
Reinhard Bauer, Frank-D. Böhmer, Daniela Reich, Tina M Schnoeder, Reinhard Fässler, Ashok Kumar Jayavelu, Florian H. Heidel, Jörg P. Müller, Anne Kresinsky, Matthias Mann, Julia Kallenbach
Publikováno v:
Leukemia. 34(5)
Autor:
Julia Kallenbach, Karin Schmelz, Paul S. Bradshaw, Marco Anders, Patrick Concannon, Stefanie Heinrich, M. Stephen Meyn, Ilja Demuth, Martin Digweed, Anika Lindner
Publikováno v:
DNA repair. 7(8)
Human SNM1B/Apollo is involved in the cellular response to DNA-damage, however, its precise role is unknown. Recent reports have implicated hSNM1B in the protection of telomeres. We have found hSNM1B to interact with TRF2, a protein which functions i