Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Julia KZHYSHKOWSKA"'
Autor:
Agnieszka Rusak, Ewa Kątnik, Tomasz Górnicki, Christina Schmuttermaier, Krzysztof Kujawa, Aleksandra Piotrowska, Katarzyna Ratajczak-Wielgomas, Alicja Kmiecik, Andrzej Wojnar, Piotr Dzięgiel, Julia Kzhyshkowska
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Chitinase-like proteins have multiple biological functions that promote tumor growth, angiogenesis and metastasis. Expression of CHI3L2, which is similar in structure to CHI3L1, is detected in glioma cells and tumor-associated macrophages (T
Externí odkaz:
https://doaj.org/article/526f44a817694ad59ee3c6dec0040c88
Autor:
Samar Elorbany, Chiara Berlato, Larissa S. Carnevalli, Eleni Maniati, Simon T. Barry, Jun Wang, Ranjit Manchanda, Julia Kzhyshkowska, Frances Balkwill
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Single-cell RNA sequencing (scRNAseq) of tumour-infiltrating immune cells in high-grade serous ovarian cancer (HGSOC) omental biopsies reveals potential targets that could enhance response to neo-adjuvant chemotherapy (NACT). Analysis of 64,
Externí odkaz:
https://doaj.org/article/b0605db9535949a2b19622478de8aefe
Autor:
Shilei Bi, Lijun Huang, Yongjie Chen, Zhenhua Hu, Shanze Li, Yifan Wang, Baoying Huang, Lizi Zhang, Yuanyuan Huang, Beibei Dai, Lili Du, Zhaowei Tu, Yijing Wang, Dan Xu, Xiaotong Xu, Wen Sun, Julia Kzhyshkowska, Haibin Wang, Dunjin Chen, Fengchao Wang, Shuang Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Abnormal trophoblast self-renewal and differentiation during early gestation is the major cause of miscarriage, yet the underlying regulatory mechanisms remain elusive. Here, we show that trophoblast specific deletion of Kat8, a MYST family
Externí odkaz:
https://doaj.org/article/a68412fcc31c4e5f985049702cf0d822
Autor:
Irina Larionova, Pavel Iamshchikov, Anna Kazakova, Militsa Rakina, Maxim Menyalo, Kadriia Enikeeva, Guzel Rafikova, Yuliya Sharifyanova, Valentin Pavlov, Alisa Villert, Larisa Kolomiets, Julia Kzhyshkowska
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide. The major clinical challenge includes the asymptomatic state of the disease, making diagnosis possible only at advanced stages. Another OC complication is the high relapse rate
Externí odkaz:
https://doaj.org/article/81c6117381f4454d8faa711578c75174
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28332- (2024)
M1/M2 paradigm of macrophage plasticity has existed for decades. Now it becomes clear that this dichotomy doesn't adequately reflect the diversity of macrophage phenotypes in tumor microenvironment (TME). Tumor-associated macrophages (TAMs) are a maj
Externí odkaz:
https://doaj.org/article/002446580b6646f4a18d2587e97e140c
Autor:
Svetlana Piatnitskaia, Guzel Rafikova, Azat Bilyalov, Svyatoslav Chugunov, Iskander Akhatov, Valentin Pavlov, Julia Kzhyshkowska
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The increasing use of medical implants in various areas of medicine, particularly in orthopedic surgery, oncology, cardiology and dentistry, displayed the limitations in long-term integration of available biomaterials. The effective functioning and s
Externí odkaz:
https://doaj.org/article/f4d6109dfb714b6a8d631114759bf5ba
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The innate immune response represents the first-line of defense against invading pathogens. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) have been implicated in various aspects of innate immune function, which involves respirator
Externí odkaz:
https://doaj.org/article/3984fe8f1d8548f3a7dfbf2effa7ae1f
Autor:
Vitaliy Chagovets, Natalia Starodubtseva, Alisa Tokareva, Anastasia Novoselova, Marina Patysheva, Irina Larionova, Elizaveta Prostakishina, Militsa Rakina, Anna Kazakova, Evgenii Topolnitskiy, Nikolay Shefer, Julia Kzhyshkowska, Vladimir Frankevich, Gennadiy Sukhikh
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionImmunometabolism is essential factor of tumor progression, and tumor-associated macrophages are characterized by substantial changes in their metabolic status. In this study for the first time, we applied targeted amino acid LC-MS/MS anal
Externí odkaz:
https://doaj.org/article/246565c522cc4e35a3507cd87442b9f4
Autor:
Lijun Huang, Zhaowei Tu, Liudan Wei, Wei Sun, Yifan Wang, Shilei Bi, Fang He, Lili Du, Jingsi Chen, Julia Kzhyshkowska, Haibin Wang, Dunjin Chen, Shuang Zhang
Publikováno v:
Advanced Science, Vol 10, Iss 26, Pp n/a-n/a (2023)
Abstract The interaction between trophoblasts, stroma cells, and immune cells at the maternal–fetal interface constitutes the functional units of the placenta, which is crucial for successful pregnancy outcomes. However, the investigation of this i
Externí odkaz:
https://doaj.org/article/112ae84dd4b247daa9a134e6d2d911e9
Autor:
João Pessoa, Maria Teresa Valenti, Nadège Bellance, Paula Chiarella, Tamrat Abebe, Lorenzo Gerratana, Carlos Pérez-Plasencia, Julia Kzhyshkowska
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/2c35ccd755f74ae4a92bf5f2976b92a1