Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Julia K. Varga"'
Autor:
Julia K. Varga, Kelsey Diffley, Katherine R. Welker Leng, Carol A. Fierke, Ora Schueler-Furman
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Histone deacetylases play important biological roles well beyond the deacetylation of histone tails. In particular, HDAC6 is involved in multiple cellular processes such as apoptosis, cytoskeleton reorganization, and protein folding, affecti
Externí odkaz:
https://doaj.org/article/fb65187a4b2e4f9da9c319970e410063
Autor:
Tomer Tsaban, Julia K. Varga, Orly Avraham, Ziv Ben-Aharon, Alisa Khramushin, Ora Schueler-Furman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
AlphaFold2 has originally been developed to provide highly accurate predictions of protein monomer structures. Here, the authors present a simple adaptation of AlphaFold2 that enables structural modeling of peptide–protein complexes, and explore th
Externí odkaz:
https://doaj.org/article/498a78dc72be44ae80a6bac350a603c6
Autor:
Chop Yan Lee, Dalmira Hubrich, Julia K Varga, Christian Schäfer, Mareen Welzel, Eric Schumbera, Milena Djokic, Joelle M Strom, Jonas Schönfeld, Johanna L Geist, Feyza Polat, Toby J Gibson, Claudia Isabelle Keller Valsecchi, Manjeet Kumar, Ora Schueler-Furman, Katja Luck
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 2, Pp 75-97 (2024)
Abstract Structural resolution of protein interactions enables mechanistic and functional studies as well as interpretation of disease variants. However, structural data is still missing for most protein interactions because we lack computational and
Externí odkaz:
https://doaj.org/article/22ace84c8c9745df8c5ea1c7bef0edf3
Autor:
Julia K. Varga, Ora Schueler‐Furman
Publikováno v:
Angewandte Chemie International Edition.
Autor:
Hugo Schweke, Qifang Xu, Gerardo Tauriello, Lorenzo Pantolini, Torsten Schwede, Frédéric Cazals, Alix Lhéritier, Juan Fernandez-Recio, Luis Ángel Rodríguez-Lumbreras, Ora Schueler-Furman, Julia K. Varga, Brian Jiménez-García, Manon F. Réau, Alexandre Bonvin, Castrense Savojardo, Pier-Luigi Martelli, Rita Casadio, Jérôme Tubiana, Haim Wolfson, Romina Oliva, Didier Barradas-Bautista, Tiziana Ricciardelli, Luigi Cavallo, Česlovas Venclovas, Kliment Olechnovič, Raphael Guerois, Jessica Andreani, Juliette Martin, Xiao Wang, Daisuke Kihara, Anthony Marchand, Bruno Correia, Xiaoqin Zou, Sucharita Dey, Roland Dunbrack, Emmanuel Levy, Shoshana Wodak
Reliably scoring and ranking candidate models of protein complexes and assigning their oligomeric state from the structure of the crystal lattice represent outstanding challenges. A community-wide effort was launched to tackle these challenges. The l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adaf2d977a6fae24f92d44626aa47f9a
https://doi.org/10.22541/au.167569565.51141128/v1
https://doi.org/10.22541/au.167569565.51141128/v1
Autor:
Sayanika Banerjee, Julia K Varga, Manoj Kumar, Guy Zoltsman, Michail N Isupov, Rina Rosenzweig, Ora Schueler-Furman, Reuven Wiener
Ufmylation, a protein modification by Ubiquitin-like (UBL) protein UFM1, plays a crucial role in several cellular processes including DNA damage response, protein translation and ER homeostasis. To date, little is known how the enzymes responsible fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12b4de593ce0314cc845c2e4640536f0
https://doi.org/10.1101/2022.09.15.508077
https://doi.org/10.1101/2022.09.15.508077