Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Julia K. Brynildsen"'
Autor:
Noah Lubben, Julia K. Brynildsen, Connor M. Webb, Howard L. Li, Cheryl E. G. Leyns, Lakshmi Changolkar, Bin Zhang, Emily S. Meymand, Mia O’Reilly, Zach Madaj, Daniella DeWeerd, Matthew J. Fell, Virginia M. Y. Lee, Dani S. Bassett, Michael X. Henderson
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-20 (2024)
Abstract Background Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson’s disease (PD). These mutations elevate the LRRK2 kinase activity, making LRRK2 kinase inhibitors an attractive therapeutic. LRRK2
Externí odkaz:
https://doaj.org/article/1f84f0e37fc14d51a4c531d8dca9e20e
Autor:
Amelia D. Dunn, Shivon A. Robinson, Chiso Nwokafor, Molly Estill, Julia Ferrante, Li Shen, Crystal O. Lemchi, Jordi Creus-Muncunill, Angie Ramirez, Juliet Mengaziol, Julia K. Brynildsen, Mark Leggas, Jamie Horn, Michelle E. Ehrlich, Julie A. Blendy
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
IntroductionInfants exposed to opioids in utero are at high risk of exhibiting Neonatal Opioid Withdrawal Syndrome (NOWS), a combination of somatic withdrawal symptoms including high pitched crying, sleeplessness, irritability, gastrointestinal distr
Externí odkaz:
https://doaj.org/article/5c02e79f5cd44978b1bd5dd7551f72ee
Autor:
Dale Zhou, Yoona Kang, Danielle Cosme, Mia Jovanova, Xiaosong He, Arun Mahadevan, Jeesung Ahn, Ovidia Stanoi, Julia K. Brynildsen, Nicole Cooper, Eli J. Cornblath, Linden Parkes, Peter J. Mucha, Kevin N. Ochsner, David M. Lydon-Staley, Emily B. Falk, Dani S. Bassett
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Mindful attention is characterized by acknowledging the present experience as a transient mental event. Early stages of mindfulness practice may require greater neural effort for later efficiency. Early effort may self-regulate behavior and focalize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ff0faa491d2315300cfce58e69254f
https://doi.org/10.1073/pnas.2201074119
https://doi.org/10.1073/pnas.2201074119
Autor:
Julia K. Brynildsen, Kechun Yang, Crystal Lemchi, John A. Dani, Mariella De Biasi, Julie A. Blendy
Publikováno v:
Neuropharmacology. 218
The single nucleotide polymorphism (SNP) D398N (rs16969968) in CHRNA5, the gene encoding the α5 subunit of the nicotinic acetylcholine receptors (nAChR), has been associated with both nicotine and opiate dependence in human populations. Expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d80a05d00ef6a50fbd2307de172911
https://pubmed.ncbi.nlm.nih.gov/35973602
https://pubmed.ncbi.nlm.nih.gov/35973602
Autor:
Dale Zhou, Yoona Kang, Danielle Cosme, Mia Jovanova, Xiaosong He, Arun Mahadevan, Ovidia Stanoi, Julia K. Brynildsen, Nicole Cooper, Eli Cornblath, Linden Parkes, Peter Mucha, Kevin Ochsner, David M. Lydon-Staley, Emily B. Falk, Danielle S Bassett
Mindfulness is characterized by attentiveness to the present experience with nonjudgmental awareness and acceptance. Practicing mindfulness alters brain function to support the executive regulation of thoughts, feelings, and behavior. While early sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6bb629d59d13ec7927fede7a6921ce9
https://doi.org/10.31234/osf.io/u83my
https://doi.org/10.31234/osf.io/u83my
Autor:
Melissa T. Manners, Darrell Eacret, Xin Liu, Max Schechter, Julie A. Blendy, Julia K. Brynildsen
Publikováno v:
Brain Behav Immun
The transcription factor CREB (cyclic AMP response element (CRE)-binding protein) is implicated in the pathophysiology and treatment of depression. Structural and functional studies in both animals and humans suggest that abnormalities of the hippoca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1930f14103791250f2dc6d3546dbd180
https://doi.org/10.1016/j.bbi.2019.06.035
https://doi.org/10.1016/j.bbi.2019.06.035
Autor:
Julie A. Blendy, Julia K. Brynildsen
Publikováno v:
Neuropharmacology
Genetics are known to be a significant risk factor for drug abuse. In human populations, the single nucleotide polymorphism (SNP) D398N in the gene CHRNA5 has been associated with addiction to nicotine, opioids, cocaine, and alcohol. In this paper, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93099464a5f966e7d5d404a76996c7b
https://pubmed.ncbi.nlm.nih.gov/33539855
https://pubmed.ncbi.nlm.nih.gov/33539855
Autor:
Julie A. Blendy, Carmen Weidler, Eli J. Cornblath, Julia K. Brynildsen, Kyla D. Mace, Fabio Pasqualetti, Danielle S. Bassett
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Persistent alterations to neural circuitry may help to explain why opiate abuse liability is higher among individuals with a history of chronic exposure. In this study, we employ a unique combination of computational approaches to unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c036ffbee1de3cdd27804a3881e1c86
https://pubmed.ncbi.nlm.nih.gov/32694207
https://pubmed.ncbi.nlm.nih.gov/32694207
Publikováno v:
Behav Brain Res
Current estimates indicate that millions of people in the United States abuse opioid drugs, which may also affect their offspring. To determine whether parental exposure to morphine alters reward and affective behaviors in subsequent generations we e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290e4b838a1c59bcf76855aeb5408317
https://pubmed.ncbi.nlm.nih.gov/32745660
https://pubmed.ncbi.nlm.nih.gov/32745660
Autor:
Isaac J. Perron, Bridgin G. Lee, Julie A. Blendy, Sangwon F. Kim, Sunghee Jin, Julia K. Brynildsen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Cigarette smoking is the leading cause of preventable disease and death in the United States. Severe withdrawal symptoms are the reason most people have a hard time quitting smoking. AMP-activated protein kinase (AMPK) is a master regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65575334b2c9224bfdc5656d3d87261
https://doi.org/10.1073/pnas.1707047115
https://doi.org/10.1073/pnas.1707047115