Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Julia K Porter"'
Publikováno v:
British Journal of Pharmacology. Sep2002, Vol. 137 Issue 1, p49. 13p.
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:1849-1853
Nicotinic receptors containing alpha7 subunits are widely distributed in the central nervous system and are thought to be involved in a number of functions. However, it has been difficult to study alpha7-containing receptors in vivo because of a pauc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66afe8f80edcc1d7a7eb49da5b2ce473
https://doi.org/10.1016/j.bmcl.2003.09.104
https://doi.org/10.1016/j.bmcl.2003.09.104
Autor:
Roger L. Papke, Julia K. Porter Papke
Publikováno v:
British Journal of Pharmacology. 137:49-61
1. Pharmacological studies of alpha7 nicotinic acetylcholine receptors are confounded by the fact that rapid desensitization to high agonist concentration causes alpha7 peak responses to occur well in advance of complete solution exchange. For this r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19ecca0128d0b5b13ad80ecfc4189d90
https://doi.org/10.1038/sj.bjp.0704833
https://doi.org/10.1038/sj.bjp.0704833
Autor:
Michael M. Francis, Ben Horenstein, J Christopher Webster, Roger L. Papke, Clare Stokes, Julia K Porter, Gillian Robinson
Publikováno v:
British Journal of Pharmacology. 127:1337-1348
We show that a portion of the TM2 domain regulates the sensitivity of beta subunit-containing rat neuronal nicotinic AChR to the ganglionic blocker mecamylamine, such that the substitution of 4 amino acids of the muscle beta subunit sequence into the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1df9adb6bf4f8a733296909360d14446
https://doi.org/10.1038/sj.bjp.0702686
https://doi.org/10.1038/sj.bjp.0702686
Autor:
Roger L. Papke, Clare Stokes, Thomas J. McCormack, William R. Kem, Julia K. Porter Papke, Nicole A. Horenstein
Publikováno v:
Molecular pharmacology. 66(1)
The alpha7 nAChR-selective partial agonist 3-(2,4-dimethoxybenzylidene)anabaseine (GTS-21) is more efficacious and potent for rat receptors than for human alpha7 receptors. Four single amino acid differences exist between human and rat alpha7 in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3989246a78d44d88b6f3d2c855efe6f0
https://pubmed.ncbi.nlm.nih.gov/15213292
https://pubmed.ncbi.nlm.nih.gov/15213292
Autor:
Sophie Lavieri, Nicole A. Horenstein, Edwin M. Meyer, Sirisha R. Bollampally, Thaddeus A.S. Papke, Roger L. Papke, Yoshitsugu Itoh, Julia K. Porter Papke
Publikováno v:
Neuropharmacology. 46(7)
Anabaseine is a marine worm toxin that is a relatively non-selective nicotinic agonist, activating both muscle-type and neuronal nicotinic acetylcholine receptors (nAChR) with varying efficacy. While anabaseine has significant activity with muscle-ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38945b2573f9b0e51c6eaf1e36d96539
https://pubmed.ncbi.nlm.nih.gov/15081799
https://pubmed.ncbi.nlm.nih.gov/15081799