Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Julia K, Krupa"'
Autor:
Suresh K. Mendu, Marta E. Stremska, Bimal N. Desai, Julia K. Krupa, Clare A. Parker, Michael S. Schappe, Eric J. Stipes, Jason S. Rogers, Justin S. A. Perry, Emily K. Moser, Thomas J. Braciale
Publikováno v:
Sci Signal
The thymic development of regulatory T (T(reg)) cells, crucial suppressors of the responses of effector T (T(eff)) cells, is governed by the transcription factor FOXP3. Despite the clinical importance of T(reg) cells, there is a dearth of druggable m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d82adb853980e9002ca0667da87e572
https://doi.org/10.1126/scisignal.abb0619
https://doi.org/10.1126/scisignal.abb0619
Autor:
Michael S. Schappe, Suresh K. Mendu, Julia K. Krupa, Eric J. Stipes, Emily K. Moser, Jason S. Rogers, Clare A. Parker, Bimal N. Desai, Thomas J. Braciale
In BriefGenetic deletion of Trpm7 in T-cells or pharmacological inhibition of TRPM7 channel promotes the development of fully functional Treg cells by increasing IL-2Rα and STAT5-dependent FOXP3 expression in the developing thymocytes. The study ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea3e524fb619577d530826fb3e9a7ea
https://doi.org/10.1101/330233
https://doi.org/10.1101/330233
Autor:
Michael S, Schappe, Kalina, Szteyn, Marta E, Stremska, Suresh K, Mendu, Taylor K, Downs, Philip V, Seegren, Michelle A, Mahoney, Sumeet, Dixit, Julia K, Krupa, Eric J, Stipes, Jason S, Rogers, Samantha E, Adamson, Norbert, Leitinger, Bimal N, Desai
Publikováno v:
Immunity. 48(1)
Toll-like receptors (TLRs) sense pathogen-associated molecular patterns to activate the production of inflammatory mediators. TLR4 recognizes lipopolysaccharide (LPS) and drives the secretion of inflammatory cytokines, often contributing to sepsis. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f2f62d7f5bbddeafebef5fef9e00da1
https://pubmed.ncbi.nlm.nih.gov/29343439
https://pubmed.ncbi.nlm.nih.gov/29343439
Autor:
Julia K. Krupa, Gregory W. Brown, Michael S. Schappe, Suresh K. Mendu, Monica W. Buckley, Yu-Hsin Chiu, Vesna Jevtovic-Todorovic, Janelle L. Weaver, Jin K Kim, Shaofang Shu, Joyce Chung, Kodi S. Ravichandran, Sanja Arandjelovic, Bimal N. Desai, Douglas A. Bayliss
Publikováno v:
Scientific Reports
Neuropathic pain symptoms respond poorly to available therapeutics, with most treated patients reporting unrelieved pain and significant impairment in daily life. Here, we show that Pannexin 1 (Panx1) in hematopoietic cells is required for pain-like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab13ca4dfc20969568f8df0b47a3d9c2
Autor:
Claire McKinley, Julia K Krupa, Bradford B. Worrall, Andrew M. Southerland, Kevin M. Barrett, James F. Meschia, Nicole A Chiota-McCollum, Blake L. Rosenbaum
Publikováno v:
Stroke. 48
Background: The risk for intracranial (IA) and abdominal aortic aneurysms (AAA) is partially heritable, with evidence mounting in favor of shared genetic risk for both. Methods: The Brain and Aortic Aneurysm Study (BAAS, NCT#17341) at University of V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9a863a7ea01d7f645d17b4195a5e746
https://doi.org/10.1161/str.48.suppl_1.wp79
https://doi.org/10.1161/str.48.suppl_1.wp79
Autor:
Norbert Leitinger, Julia K. Krupa, Kalina Szteyn, Taylor K Downs, Eric J. Stipes, Jason S. Rogers, Bimal N. Desai, Marta E. Stremska, Michelle A. Mahoney, Philip V. Seegren, Michael S. Schappe, Samantha E. Adamson, Suresh K. Mendu, Sumeet Dixit
Publikováno v:
Immunity. 48:59-74.e5
Toll-like receptors (TLRs) sense pathogen-associated molecular patterns to activate the production of inflammatory mediators. TLR4 recognizes lipopolysaccharide (LPS) and drives the secretion of inflammatory cytokines, often contributing to sepsis. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::860a3b496cc6be489272cb40bc2de44e
https://doi.org/10.1016/j.immuni.2017.11.026
https://doi.org/10.1016/j.immuni.2017.11.026