Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Julia Joung"'
Autor:
Julia Joung, Paul C. Kirchgatterer, Ankita Singh, Jang H. Cho, Suchita P. Nety, Rebecca C. Larson, Rhiannon K. Macrae, Rebecca Deasy, Yuen-Yi Tseng, Marcela V. Maus, Feng Zhang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Loss-of-function CRISPR-based screens have identified several genes associated with cancer resistance to T cell-induced cytotoxicity. Here the authors perform a genome-scale, gain-of-function CRISPR screen and identify candidate genes, including the
Externí odkaz:
https://doaj.org/article/a70e38758d81453c93fd04c1608e57b4
Autor:
Man Nie, Likun Du, Weicheng Ren, Julia Joung, Xiaofei Ye, Xi Shi, Sibel Ciftci, Dongbing Liu, Kui Wu, Feng Zhang, Qiang Pan-Hammarström
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-11 (2021)
Abstract Diffuse large B-cell lymphoma (DLBCL) is the most common type of aggressive lymphoid malignancy and a highly heterogeneous disease. In this study, we performed whole-genome and transcriptome sequencing, and a genome-wide CRISPR-Cas9-knockout
Externí odkaz:
https://doaj.org/article/b9069402ae794d37b6e1f0f69aa5692f
Autor:
Marcela Maus, Rebecca Larson, Irene Scarfò, Max Jan, Stefanie Bailey, Amanda Bouffard, Michael Kann, Nicholas Haradhvala, Kai Stewart, Mark Leick, Trisha Berger, Julia Joung, Tamara Ouspenskaia, Travis Law, Aviv Regev, Gad Getz
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/92a54c122b9345659d7a4724b6e5bf0f
Autor:
Raphaella W. L. So, Sai Wai Chung, Heather H. C. Lau, Jeremy J. Watts, Erin Gaudette, Zaid A. M. Al-Azzawi, Jossana Bishay, Lilian Tsai-Wei Lin, Julia Joung, Xinzhu Wang, Gerold Schmitt-Ulms
Publikováno v:
Molecular Neurodegeneration, Vol 14, Iss 1, Pp 1-16 (2019)
Abstract The adoption of CRISPR-Cas9 technology for functional genetic screens has been a transformative advance. Due to its modular nature, this technology can be customized to address a myriad of questions. To date, pooled, genome-scale studies hav
Externí odkaz:
https://doaj.org/article/3ec4297f568f430e9abc28d7d2b76c06
Autor:
Bernhard Schermer, Francesca Fabretti, Maximilian Damagnez, Veronica Di Cristanziano, Eva Heger, Sita Arjune, Nathan A Tanner, Thomas Imhof, Manuel Koch, Alim Ladha, Julia Joung, Jonathan S Gootenberg, Omar O Abudayyeh, Volker Burst, Feng Zhang, Florian Klein, Thomas Benzing, Roman-Ulrich Müller
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0238612 (2020)
BackgroundRapid and extensive testing of large parts of the population and specific subgroups is crucial for proper management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and decision-making in times of a pandemic outbr
Externí odkaz:
https://doaj.org/article/d5e7d69119164d80be6a22fed0519fa1
Autor:
Maturada Patchsung, Aimorn Homchan, Kanokpol Aphicho, Surased Suraritdechachai, Thanyapat Wanitchanon, Archiraya Pattama, Khomkrit Sappakhaw, Piyachat Meesawat, Thanakrit Wongsatit, Artittaya Athipanyasilp, Krittapas Jantarug, Niracha Athipanyasilp, Juthamas Buahom, Supapat Visanpattanasin, Nootaree Niljianskul, Pimchai Chaiyen, Ruchanok Tinikul, Nuanjun Wichukchinda, Surakameth Mahasirimongkol, Rujipas Sirijatuphat, Nasikarn Angkasekwinai, Michael A. Crone, Paul S. Freemont, Julia Joung, Alim Ladha, Omar Abudayyeh, Jonathan Gootenberg, Feng Zhang, Claire Chewapreecha, Sittinan Chanarat, Navin Horthongkham, Danaya Pakotiprapha, Chayasith Uttamapinant
Publikováno v:
The CRISPR Journal. 6:99-115
Point-of-care (POC) nucleic acid detection technologies are poised to aid gold-standard technologies in controlling the COVID-19 pandemic, yet shortcomings in the capability to perform critically needed complex detection—such as multiplexed detecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7cf825691d9235e5397f9efd93a5624
https://doi.org/10.1089/crispr.2022.0048
https://doi.org/10.1089/crispr.2022.0048
Autor:
Dongbing Liu, Julia Joung, Xiaofei Ye, Kui Wu, Weicheng Ren, Man Nie, Sibel Ciftci, Feng Zhang, Likun Du, Xi Shi, Qiang Pan-Hammarström
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Diffuse large B-cell lymphoma (DLBCL) is the most common type of aggressive lymphoid malignancy and a highly heterogeneous disease. In this study, we performed whole-genome and transcriptome sequencing, and a genome-wide CRISPR-Cas9-knockout screen t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e43e7cfba1cdcbbd8a9b1d01b1ab8da
https://doaj.org/article/b9069402ae794d37b6e1f0f69aa5692f
https://doaj.org/article/b9069402ae794d37b6e1f0f69aa5692f
Autor:
Michael-John Dolan, Martine Therrien, Saša Jereb, Tushar Kamath, Trevor Atkeson, Samuel E. Marsh, Aleksandrina Goeva, Neal M. Lojek, Sarah Murphy, Cassandra M. White, Julia Joung, Bingxu Liu, Francesco Limone, Kevin Eggan, Nir Hacohen, Bradley E. Bernstein, Christopher K. Glass, Ville Leinonen, Mathew Blurton-Jones, Feng Zhang, Charles B. Epstein, Evan Z. Macosko, Beth Stevens
Microglia have emerged as key players in the pathogenesis of neurodegenerative conditions such as Alzheimer’s disease (AD). In response to CNS stimuli, these cells adopt distinct transcriptional and functional subtypes known as states. However, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0f1768dc9f0a17a674fe00e9a861fa7
https://doi.org/10.1101/2022.05.02.490100
https://doi.org/10.1101/2022.05.02.490100
Autor:
Julia Joung, Sai Ma, Tristan Tay, Kathryn R. Geiger-Schuller, Paul C. Kirchgatterer, Vanessa K. Verdine, Baolin Guo, Mario A. Arias-Garcia, William E. Allen, Ankita Singh, Olena Kuksenko, Omar O. Abudayyeh, Jonathan S. Gootenberg, Zhanyan Fu, Rhiannon K. Macrae, Jason D. Buenrostro, Aviv Regev, Feng Zhang
Publikováno v:
Cell. 186(1)
Transcription factors (TFs) regulate gene programs, thereby controlling diverse cellular processes and cell states. To comprehensively understand TFs and the programs they control, we created a barcoded library of all annotated human TF splice isofor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837a714484416964b4e991d1d7162945
https://pubmed.ncbi.nlm.nih.gov/36608654
https://pubmed.ncbi.nlm.nih.gov/36608654
Autor:
Julia Joung, Paul C. Kirchgatterer, Ankita Singh, Jang H. Cho, Suchita P. Nety, Rebecca C. Larson, Rhiannon K. Macrae, Rebecca Deasy, Yuen-Yi Tseng, Marcela V. Maus, Feng Zhang
Publikováno v:
Nature communications. 13(1)
The cellular processes that govern tumor resistance to immunotherapy remain poorly understood. To gain insight into these processes, here we perform a genome-scale CRISPR activation screen for genes that enable human melanoma cells to evade cytotoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76fa527058a2a5cfbe74757c889d3eae
https://pubmed.ncbi.nlm.nih.gov/35338135
https://pubmed.ncbi.nlm.nih.gov/35338135