Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Julia J. Inglis"'
Early induction of uncoupling protein-2 in pulmonary macrophages in hyperoxia-associated lung injury
Autor:
Julia J Inglis, James H. Steer, David A. Joyce, Huey S Yap, Tracy S. Mann, Susan Z.Y. Lo, Peter J. Henry
Publikováno v:
Inhalation Toxicology. 25:544-552
High concentrations of inspired oxygen contribute to the pathogenesis of neonatal bronchopulmonary dysplasia and adult acute respiratory distress syndrome. Animal models of hyperoxia-associated lung injury (HALI) are characterized by enhanced generat
Autor:
Jane P. Hughes, Praveen Anand, Saba Alzabin, Richard O. Williams, Marc Feldmann, Julia J. Inglis, Kay McNamee
Interleukin-17 (IL-17) and tumour necrosis factor-α (TNF) are critical in the pathogenesis of arthritis but their relationship during inflammatory pain has received limited attention. We aimed to establish whether IL-17 can induce hyperalgesia in ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d3082e6061d0557104d5a8a647da8a
https://doi.org/10.1016/j.pain.2011.03.035
https://doi.org/10.1016/j.pain.2011.03.035
Autor:
Stefan K. Drexler, Gertraud Orend, Masahide Kashiwagi, Brian M. J. Foxwell, Nidhi Sofat, Kim S. Midwood, Anna M. Piccinini, Fionula M. Brennan, Annette Trebaul, Julia J. Inglis, Sandra Sacre, Emma Chan
Although there have been major advances in the treatment of rheumatoid arthritis with the advent of biological agents, the mechanisms that drive cytokine production and sustain disease chronicity remain unknown. Tenascin-C (encoded by Tnc) is an extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48423056d64128ee92e3cbde0848d11
https://ora.ox.ac.uk/objects/uuid:ebf9d5c3-59db-45a1-bb51-3977370733e4
https://ora.ox.ac.uk/objects/uuid:ebf9d5c3-59db-45a1-bb51-3977370733e4
OBJECTIVE: Indoleamine 2,3 dioxygenase (IDO) is a catabolic enzyme that initiates the kynurenine pathway of tryptophan degradation and has immunomodulatory properties. The aim of this study was to investigate the regulation of collagen-induced arthri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a8fd5512083c82411f6e7eba1d570c
https://ora.ox.ac.uk/objects/uuid:aff2a820-789c-4d30-82ca-c8da5b6c2237
https://ora.ox.ac.uk/objects/uuid:aff2a820-789c-4d30-82ca-c8da5b6c2237
Autor:
Luke L. Gompels, Julia J. Inglis, Tonia L. Vincent, Ngee Han Lim, Leigh Madden, Ellen McConnell, Dorian O. Haskard, Ewa M. Paleolog
Publikováno v:
Arthritis & Rheumatism. 63:107-117
Objective In vivo optical imaging can delineate at the macroscopic level processes that are occurring at the cellular and molecular levels. E-selectin, a leukocyte adhesion molecule expressed on endothelium, is induced by tumor necrosis factor α (TN
Publikováno v:
Current Rheumatology Reviews. 6:194-207
Rheumatoid arthritis (RA) and Osteoarthritis (OA) are both common diseases of the joints. RA is distinguished by inflammation and synovitis leading to joint destruction, whereas OA is typified by degenerative and mostly noninflammatory disease. Altho
Autor:
Philip Kong, Alberto Mantovani, Amir S. Yazdi, Cecilia Garlanda, Fionula M. Brennan, Brian M. J. Foxwell, Stefan K. Drexler, Marc Feldmann, Richard O. Williams, Julia J. Inglis
Publikováno v:
Arthritis & Rheumatism. 62:2249-2261
Objective Single-immunoglobulin interleukin-1 receptor–related (SIGIRR), which is also known as Toll/interleukin-1 receptor 8 (TIR-8), is a member of the TIR domain–containing family of receptors and was first characterized as an inhibitor of int
Publikováno v:
Arthritis & Rheumatism. 62:171-178
Objective To assess the therapeutic potential of anti-CD3 monoclonal antibodies (mAb) for rheumatoid arthritis, using collagen-induced arthritis as an animal model. Methods Arthritis was induced in DBA/1 mice by immunization with type II collagen. Af
Publikováno v:
Brain Research Reviews. 60:187-201
Non-malignant musculoskeletal pain is the most common clinical symptom that causes patients to seek medical attention and is a major cause of disability in the world. Musculoskeletal pain can arise from a variety of common conditions including osteoa
Autor:
Stephen P. Hunt, Kay McNamee, Marc Feldmann, Richard O. Williams, Shi-Lu Chia, Julia J. Inglis, David Essex, Tonia L. Vincent
Publikováno v:
Arthritis & Rheumatism. 58:3110-3119
Objective OA is the most common joint disease, affecting 10–15% of people over 60 years of age. However, up to 40% of individuals with radiologic damage are asymptomatic. The purpose of this study was to assess the role of the endogenous opioid sys