Equine herpesviruses: a roundtable discussion

Autor: Simon Knapp, Neil Bryant, J. Richard Newton, David Rendle, Julia H. Kydd, Huw Neal, James R. Crabtree, Sarah Moore, Philip Ivens

Publikováno v: UK-Vet Equine. 3:1-12

Foreword There are nine different equid herpesviruses (EHVs). Five types (EHV-1 to EHV-5) infect the domestic horse, while EHV-6 to EHV-9 are associated with infections in wild equids including asses and zebra. This review focuses on the commonest an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7d7d60c06aa67bbbeac31f94982ba036
https://doi.org/10.12968/ukve.2019.3.s2.1

A point mutation in a herpesvirus polymerase determines neuropathogenicity.

Autor: Laura B Goodman, Arianna Loregian, Gillian A Perkins, Josie Nugent, Elizabeth L Buckles, Beatrice Mercorelli, Julia H Kydd, Giorgio Palù, Ken C Smith, Nikolaus Osterrieder, Nicholas Davis-Poynter

Publikováno v: PLoS Pathogens, Vol 3, Iss 11, p e160 (2007)

Infection with equid herpesvirus type 1 (EHV-1) leads to respiratory disease, abortion, and neurologic disorders in horses. Molecular epidemiology studies have demonstrated that a single nucleotide polymorphism resulting in an amino acid variation of

Externí odkaz: https://doaj.org/article/444beca4dfd24d999d93228f3c757677

Vaccination of foals with a modified live, equid herpesvirus-1 gM deletion mutant (RacHΔgM) confers partial protection against infection

Autor: Julia H. Kydd, Robert S Robinson, Duncan Hannant, Nikolaus Osterrieder, Neil Bryant

Publikováno v: Vaccine. 38(2)

Equid herpesvirus-1 (EHV-1) causes respiratory and neurological disease and late gestation abortion in pregnant mares. Current vaccines contain either inactivated or live EHV-1, but fail to provide complete clinical or virological protection, namely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23f62ab9999450531e364d970cf2e0b
https://pubmed.ncbi.nlm.nih.gov/31629571

Failure to detect equid herpesvirus types 1 and 4 DNA in placentae and healthy new-born Thoroughbred foals

Autor: Martin L. Schulman, Julia H. Kydd, Lara J. Brown, Geoff Brown, Tom A.E. Stout

Publikováno v: Journal of the South African Veterinary Association, Volume: 90, Issue: 1, Pages: 1-5, Published: 2019
Journal of the South African Veterinary Association, Vol 90, Iss 0, Pp e1-e5 (2019)
Journal of the South African Veterinary Association

Equid herpesvirus type 1 is primarily a respiratory tract virus associated with poor athletic performance that can also cause late gestation abortion, neonatal foal death and encephalomyelopathy. Horizontal transmission is well described, whereas evi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4fee1b44f54c1a37dcb5032d282c97
http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S1019-91282019000100006&lng=en&tlng=en

Immediate-early protein of equid herpesvirus type 1 as a target for cytotoxic T-lymphocytes in the Thoroughbred horse

Autor: Julia H. Kydd, Jean-Christophe Audonnet, Bettina Wagner, Douglas F. Antczak, Julius Minke, Ruth Case

Publikováno v: Journal of General Virology. 95:1783-1789

Cytotoxic T-lymphocytes (CTLs) are associated with protective immunity against disease caused by equid herpesvirus type 1 (EHV-1). However, the EHV-1 target proteins for CTLs are poorly defined. This limits the development of vaccine candidates desig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe15973dea0ce39e236b6151a18fa6f
https://doi.org/10.1099/vir.0.065888-0