Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Julia Gilden"'
Autor:
Jamison Grailer, Julia Gilden, Pete Stecha, Jim Hartnett, Vanessa Ott, Michael Slater, Dan Lazar, Zhijie Jey Cheng
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/e7a26181ad7e4ce1a8140cb45ef98a4e
Autor:
Jun Wang, Julia Gilden, Denise Garvin, Pete Stecha, Jim Hartnett, Frank Fan, Mei Cong, Jamison Grailer
Publikováno v:
Cancer Research. 83:3274-3274
Programmed cell death protein 1 (PD-1) is an immune checkpoint (IC) receptor that negatively regulates T cell function. Blocking the interaction of PD-1 with its ligands PD-L1 or PD-L2 unleashes the immune system and enhances anti-tumor responses. Im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e751010dffbadbdee6c980f6aa3f527f
https://doi.org/10.1158/1538-7445.am2023-3274
https://doi.org/10.1158/1538-7445.am2023-3274
Autor:
Maggie Bach, Natasha Karassina, Julia Gilden, Donna Leippe, Mike Valley, Kayla Sylvester, Jolanta Vidugiriene
Publikováno v:
Cancer Research. 83:4162-4162
Cellular energy metabolism is crucial for cell survival and the balance of metabolic pathways determines the health of the cell. Determining and understanding metabolic profiles of cells can aid in overall insight of cell health and improvement of ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8552293d520940ab7760934b2797fb0c
https://doi.org/10.1158/1538-7445.am2023-4162
https://doi.org/10.1158/1538-7445.am2023-4162
Autor:
Jun Wang, Julia Gilden, Denise Garvin, Zhi-jie Jey Cheng, Jim Hartnett, Pete Stecha, Jamison Grailer, Mei Cong, Frank Fan
Publikováno v:
Current Protocols. 1
Antibody Fc effector function is one of the main mechanisms of action (MoA) for therapeutic monoclonal antibodies. Measurement of antibody-dependent cellular cytotoxicity (ADCC) is critical for understanding the Fc effector function during monoclonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf5f0a112060b249642a99478821f4d
https://doi.org/10.1002/cpz1.296
https://doi.org/10.1002/cpz1.296
Autor:
Pete Stecha, Jun Wang, Denise Garvin, Julia Gilden, Jamison Grailer, Jim Hartnett, Frank Fan, Mei Cong, Zhi-jie Jey Cheng
Publikováno v:
Cancer Research. 82:4249-4249
Fc effector function is one of the main mechanisms of action (MoA) for therapeutic monoclonal antibodies (mAbs). Quantitative measurement of antibody-dependent cellular cytotoxicity (ADCC) is critically required for understanding the Fc function in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4552569888df317ecf6a0156209000f0
https://doi.org/10.1158/1538-7445.am2022-4249
https://doi.org/10.1158/1538-7445.am2022-4249
Autor:
Jamison Grailer, Julia Gilden, Jun Wang, Denise Garvin, Pete Stecha, Jim Hartnett, Steven Edenson, Frank Fan, Mei Cong, Zhi-jie Jey Cheng
Publikováno v:
Cancer Research. 82:1875-1875
Programmed death 1 (PD-1) is an immune checkpoint (IC) receptor that negatively regulates T-cell immune function. Blocking the interaction of PD-1 with its ligand PD-L1 unleashes the immune system and enhances anti-tumor responses. Immunotherapy usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b53c52ff3c03505d81f63e8230d662a
https://doi.org/10.1158/1538-7445.am2022-1875
https://doi.org/10.1158/1538-7445.am2022-1875
Autor:
Julia Gilden, Jamison Grailer, Michael Slater, Pete Stecha, Jim Hartnett, Dan Lazar, Gopal Krishnan, Frank Fan, Mei Cong, Zhijie Jey Cheng
Publikováno v:
Cancer Research. 82:2750-2750
Redirected T cell therapies represent a new paradigm for cancer treatment. Two main approaches for T-cell-based therapies involve molecular T cell redirection by CD3 bispecific molecules such as bispecific T-cell engagers (BiTE) and cellular T cell r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a78fc2d65b6b43b14c0ea2522a837973
https://doi.org/10.1158/1538-7445.am2022-2750
https://doi.org/10.1158/1538-7445.am2022-2750
Autor:
Denise Garvin, Pete Stecha, Mei Cong, Jamison Grailer, Jim Hartnett, Michael Beck, Jun Wang, Gopal Krishnan, Zhi-Jie Cheng, Frank Fan, Julia Gilden
Publikováno v:
Late-breaking abstracts.
Background The human immune system is comprised of a complex network of immune checkpoint receptors that are promising new immunotherapy targets for the treatment of a variety of cancers and autoimmune disorders. The Nobel prize for Medicine in 2018
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90d17289bdf4535bed93d33b2bd99e36
https://doi.org/10.1136/jitc-2020-sitc2020.0780
https://doi.org/10.1136/jitc-2020-sitc2020.0780
Autor:
Mei Cong, Pete Stecha, Jim Hartnett, Vanessa Ott, Jamison Grailer, Dan Lazar, Michael R. Slater, Frank Fan, Julia Gilden, Zhi-jie Jey Cheng
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Two main approaches for T cell-based therapies involve molecular T cell redirection by CD3 bispecific molecules such as bispecific T-cell engagers (BiTE) and cellular T cell redirection by genetic modification of T cells with chimeric anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356d83c3504aece53e0cc5a9cd0f0655
https://doaj.org/article/e7a26181ad7e4ce1a8140cb45ef98a4e
https://doaj.org/article/e7a26181ad7e4ce1a8140cb45ef98a4e
Autor:
Mei Cong, Frank Fan, Jim Hartnett, Jamison Grailer, Julia Gilden, Zhi-jie Jey Cheng, Jun Wang, Denise Garvin, Pete Stecha, Michael Beck
Publikováno v:
Cancer Research. 81:1650-1650
Immune checkpoint (IC) receptors play critical roles in maintaining immune homeostasis and are emerged as promising drug targets for the treatment of various cancers and autoimmune disorders. Monoclonal antibodies designed to block immune inhibitory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d91d25e0f0e573444ad76359636cb24f
https://doi.org/10.1158/1538-7445.am2021-1650
https://doi.org/10.1158/1538-7445.am2021-1650