Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Julia Gensheimer"'
Autor:
Paul G. Ayoub, Julia Gensheimer, Lindsay Lathrop, Colin Juett, Jason Quintos, Kevin Tam, Jack Reid, Feiyang Ma, Curtis Tam, Grace E. McAuley, Devin Brown, Xiaomeng Wu, Ruixue Zhang, Kathryn Bradford, Roger P. Hollis, Gay M. Crooks, Donald B. Kohn
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 4, Pp 101323- (2024)
X-linked lymphoproliferative disease (XLP1) results from SH2D1A gene mutations affecting the SLAM-associated protein (SAP). A regulated lentiviral vector (LV), XLP-SMART LV, designed to express SAP at therapeutic levels in T, NK, and NKT cells, is cr
Externí odkaz:
https://doaj.org/article/af4d633eb4eb4c8ea8d67abff5e5fe26
Autor:
William H. Hudson, Nataliya Prokhnevska, Julia Gensheimer, Rama Akondy, Donald J. McGuire, Rafi Ahmed, Haydn T. Kissick
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Long noncoding RNA (lncRNA) genes do not encode protein products yet are emerging as key regulators of cellular processes such as transcription and translation. Here, by examining lncRNA profiles from human and mouse CD8 T cells, the authors show tha
Externí odkaz:
https://doaj.org/article/3fba6bfb088047b99a9728dd3fed18bd
Autor:
Haydn T. Kissick, Warren J. Leonard, Andreas Wieland, Jian-Xin Lin, Se Jin Im, Rajesh M. Valanparambil, Rafi Ahmed, Gordon J. Freeman, Peng Li, Masao Hashimoto, Julia Gensheimer, Bogumila T. Konieczny, William H. Hudson
Publikováno v:
Immunity
T cell dysfunction is a characteristic feature of chronic viral infection and cancer. Recent studies in chronic lymphocytic choriomeningitis virus (LCMV) infection have defined a PD-1(+) Tcf-1(+) CD8(+) T cell subset capable of self-renewal and diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c0522783fd7c3e71a763304e0cec5f
https://europepmc.org/articles/PMC6920571/
https://europepmc.org/articles/PMC6920571/
Autor:
Alexandra Wright, Morgan Blair, Shane A. Autry, Julia Gensheimer, Morgan Gruner, Kevin M. Williams, Nathan I. Hammer
Publikováno v:
Inorganica Chimica Acta. 458:163-170
The compound [Pt(Et2dien)Cl]Cl, where Et2dien = N,N-diethyldiethylenetriamine, has been synthesized and reacted with N-acetylmethionine (N-AcMet) and guanosine 5′-monophosphate (5′-GMP). Reaction with 5′-GMP at pH 4 leads to formation of [Pt(Et
Autor:
Rafi Ahmed, William H. Hudson, Donald J. McGuire, Nataliya Prokhnevska, Julia Gensheimer, Rama Akondy, Haydn T. Kissick
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
In response to viral infection, CD8+ T cells undergo expansion and differentiate into distinct classes of effector cells. After clearance of the virus, a small population of long-lived memory cells persists. Comprehensive studies have defined the pro
Publikováno v:
Cancer Immunology Research. 7:A196-A196
CD8+ T-cells are responsible for detection and killing of hosT-cells expressing non-self proteins. Upon antigen persistence, as in cancer or chronic viral infection, antigen-specific CD8+ T-cells lose their effector function, a phenomenon known as T-