Axon guidance by growth-rate modulation

Autor: Timothy G. Vaughan, Irina Vetter, Geoffrey J. Goodhill, Julia Feldner, Duncan Mortimer, Andrew W. Thompson, Zac Pujic

Publikováno v: Proceedings of the National Academy of Sciences. 107:5202-5207

Guidance of axons by molecular gradients is crucial for wiring up the developing nervous system. It often is assumed that the unique signature of such guidance is immediate and biased turning of the axon tip toward or away from the gradient. However,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4912cc1eee48e03ab992309ed2180605
https://doi.org/10.1073/pnas.0909254107

A Bayesian model predicts the response of axons to molecular gradients

Autor: Geoffrey J. Goodhill, Kevin Burrage, Irina Vetter, Duncan Mortimer, Peter Dayan, Zac Pujic, Julia Feldner, Timothy G. Vaughan, William J. Rosoff, Linda J. Richards

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America

Axon guidance by molecular gradients plays a crucial role in wiring up the nervous system. However, the mechanisms axons use to detect gradients are largely unknown. We first develop a Bayesian “ideal observer” analysis of gradient detection by a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5790ebc3767610e13fca0cae6994212d
https://doi.org/10.1073/pnas.0900715106

L1.1 Is Involved in Spinal Cord Regeneration in Adult Zebrafish

Autor: Thomas Becker, Julia Feldner, Melitta Schachner, Catherina G. Becker, Fabio Morellini, Bettina C Lieberoth

Publikováno v: Becker, C G, Lieberoth, B C, Morellini, F, Feldner, J, Becker, T & Schachner, M 2004, ' L1.1 is involved in spinal cord regeneration in adult zebrafish ', Journal of Neuroscience, vol. 24, no. 36, pp. 7837-42 . https://doi.org/10.1523/JNEUROSCI.2420-04.2004

Adult zebrafish, in contrast to mammals, regrow axons descending from the brainstem after spinal cord transection. L1.1, a homolog of the mammalian recognition molecule L1, is upregulated by brainstem neurons during axon regrowth. However, its functi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73dfb45a0352c4fe039856373ef29159
https://doi.org/10.1523/jneurosci.2420-04.2004

PlexinA3 restricts spinal exit points and branching of trunk motor nerves in embryonic zebrafish

Autor: Julia Feldner, Thomas Becker, Björn Wendik, Catherina G. Becker, Dirk Meyer, Jörn Schweitzer, Michell M. Reimer

Publikováno v: Feldner, J, Reimer, M M, Schweitzer, J, Wendik, B, Meyer, D, Becker, T & Becker, C G 2007, ' PlexinA3 restricts spinal exit points and branching of trunk motor nerves in embryonic zebrafish ', Journal of Neuroscience, vol. 27, no. 18, pp. 4978-83 . https://doi.org/10.1523/JNEUROSCI.1132-07.2007

The pioneering primary motor axons in the zebrafish trunk are guided by multiple cues along their pathways. Plexins are receptor components for semaphorins that influence motor axon growth and path finding. We cloned plexinA3 in zebrafish and localiz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3ae07f425ee24a979d6024981abd2d
https://www.pure.ed.ac.uk/ws/files/8283671/PlexinA3_restricts_spinal_exit_points_and_branching_of_trunk_motor_nerves_in_embryonic_zebrafish.pdf

PNA microarrays for hybridisation of unlabelled DNA samples

Autor: Anette Jacob, Heinrich F. Arlinghaus, Julia Feldner, Achim Stephan, Ole Brandt, Markus Schröder, Jörg D. Hoheisel, Martina Schnölzer

Several strategies have been developed for the production of peptide nucleic acid (PNA) microarrays by parallel probe synthesis and selective coupling of full-length molecules. Such microarrays were used for direct detection of the hybridisation of u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42269e6a94fabe87d1bf14c5b860412c
https://europepmc.org/articles/PMC206485/