Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Julia Engert"'
Autor:
Andreas Schmitt, Philipp Rödel, Cihad Anamur, Claudine Seeliger, Andreas B Imhoff, Elmar Herbst, Stephan Vogt, Martijn van Griensven, Gerhard Winter, Julia Engert
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118937 (2015)
Regeneration after surgery can be improved by the administration of anabolic growth factors. However, to locally maintain these factors at the site of regeneration is problematic. The aim of this study was to develop a matrix system containing human
Externí odkaz:
https://doaj.org/article/1aa8f45602cf44e48b9881c56d8a523a
Publikováno v:
Journal of Pharmaceutical Sciences. 109:375-379
Protein aggregates and subvisible particles (SbvP), inherently present in all marketed protein drug products, have received increasing attention by health authorities. Dynamic imaging analysis was introduced to visualize SbvP and facilitate understan
Autor:
Julia Engert, Martin Peter Neubauer, Andreas Fery, Thomas Scheibel, Claudia Blüm, Elisa Agostini
Publikováno v:
Biomaterials science. 1(11)
Spider silk fibers are well known for their mechanical properties, and they are therefore in the focus of materials scientists. Additionally, silks display biocompatibility making them interesting materials for applications in medicine or cosmetics.
Autor:
Cihad Anamur, Julia Engert, Peter Lell, Christian Fellner, Laura Engelke, Julia Stadler, Stefan Henke, Gerhard Winter, Mathias Ritzmann, Susanne Zöls
Publikováno v:
International Journal of Pharmaceutics. 545:215-228
Epidermal powder immunization (EPI) is an alternative technique to the classical immunization route using needle and syringe. In this work, we present the results of an in vivo pilot study in piglets using a dried influenza model vaccine which was ap
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 128:119-130
The intradermal delivery of biologics has long been recognized as attractive approach for cutaneous immunotherapy, particularly vaccination. Although intradermal (i.d.) or subcutaneous (s.c.) injection provide reproducible dosing and good cost- and d
Publikováno v:
International Journal of Pharmaceutics. 532:13-20
Spider silk proteins for applications in drug delivery have attracted an increased interest during the past years. Some possible future medical applications for this biocompatible and biodegradable material are scaffolds for tissue engineering, impla
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 117:244-255
Solid lipid implants (SLIs) prepared by twin-screw (tsc) extrusion represent a promising technology platform for the sustained release of pharmaceutical proteins. In this work, we report on two aspects, long-term release and stability of released pro
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 114:79-87
Much effort has been put in the development of specific anti-tumour immunotherapies over the last few years, and several studies report on the use of liposomal carriers for tumour-associated antigens. In this work, the use of lipid implants, prepared
Autor:
René Brecht, Gerhard Winter, Jana Reuschel, Teresa Kraus, Julia Engert, Ulrike Schließer, Annika Lubitz, Christoph Giese
Publikováno v:
Journal of pharmaceutical sciences. 108(7)
The immunogenicity of protein aggregates has been investigated in numerous studies. Nevertheless, it is still unknown which kind of protein aggregates enhance immunogenicity the most. The ability of the currently used in vitro and in vivo systems reg
Autor:
Martina B. Schierling, Christian Hotz, Thomas Scheibel, Ute Slotta, Heike M. Herold, Julia Engert, Carole Bourquin, Thibaud Spinetti, Tina Herbst, Gerhard Winter, Inès Mottas, Lin Römer, Matthias Lucke
Publikováno v:
Biomaterials, Vol. 172 (2018) pp. 105-115
The generation of strong T-cell immunity is one of the main challenges for the development of successful vaccines against cancer and major infectious diseases. Here we have engineered spider silk particles as delivery system for a peptide-based vacci