Výsledky vyhledávání - "Julia E.C. van Steenhoven"

Assessment of tumour proliferation by use of the mitotic activity index, and Ki67 and phosphohistone H3 expression, in early‐stage luminal breast cancer

Autor: Anne Kuijer, Paul J. van Diest, Robert Kornegoor, Thijs van Dalen, Gijs van Leeuwen, Julia E.C. van Steenhoven, Joost van Gorp

Publikováno v: Histopathology

AIMS Phosphohistone H3 (PhH3) has been proposed as a novel proliferation marker in breast cancer. This study compares the interobserver agreement for assessment of the mitotic activity index (MAI), Ki67 expression, and PhH3 in a cohort of oestrogen r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5726aed671391288d72f43424c44096
https://doi.org/10.1111/his.14185

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Abstract P2-14-19: Patients’ experience with 70-gene signature testing on adjuvant systemic treatment decisions: Results of a prospective cohort study

Autor: Bianca M den Dekker, Thijs van Dalen, Paul J. van Diest, Julia E.C. van Steenhoven, Anne Kuijer, Sabine Siesling, Sjoerd G. Elias

Publikováno v: Cancer Research. 80:P2-14

Background: Early stage breast cancer patients are often confronted with uncertainty regarding the decision to undergo adjuvant chemotherapy (CT). Gene-expression profiles (GEP) are used to gain additional prognostic information and can influence adj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fbb8c734f6712684fcb660b63916c2f3
https://doi.org/10.1158/1538-7445.sabcs19-p2-14-19

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Quantifying the Mitigating Effects of Whole-Breast Radiotherapy and Systemic Treatments on Regional Recurrence Incidence Among Breast Cancer Patients

Autor: Julia E.C. van Steenhoven, Thijs van Dalen, Anne Kuijer, Liesbeth J. Boersma, Sabine Siesling, Marjolein L. Smidt, Marleen M. Roos, Marissa C. van Maaren, Sjoerd G. Elias, Paul J. van Diest

Publikováno v: Annals of surgical oncology, 27(9), 3402-3411. Springer
Annals of Surgical Oncology
Annals of Surgical Oncology, 27(9), 3402-3411. Springer, Cham

Background Despite the potential for residual lymph node metastases after a negative or positive sentinel lymph node biopsy (SLNB), breast cancer patients rarely experience regional recurrences (RRs). This study aimed to quantify the effects of nonsu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ac6d64012d10bc9385ad4420f2a48fb
https://research.utwente.nl/en/publications/9187f569-31f2-4615-b93d-81fa515f72a2

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70-Gene Signature and Tumor-Stroma Ratio Select Different Groups of Patients with Breast Cancer at Risk for Recurrence

Autor: Julia E.C. van Steenhoven, Marloes A Smit, Wilma E. Mesker, Thijs van Dalen, Rob A. E. M. Tollenaar, Paul J. van Diest

Publikováno v: Journal of Surgery and Research, 3(2), 112-118. Fortune Journals

Background: Strategies for breast cancer care are improving. However, there is a clinical need for a better selection of patients who are at risk for recurrence and benefit from treatment with chemotherapy. The 70-gene signature (70-GS) guides chemot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911f991897cbf239de8b4486477e2040
https://doi.org/10.26502/jsr.10020062

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Regional Recurrence Risk Following a Negative Sentinel Node Procedure Does Not Approximate the False-Negative Rate of the Sentinel Node Procedure in Breast Cancer Patients Not Receiving Radiotherapy or Systemic Treatment

Autor: Marleen M. Roos, Thijs van Dalen, Sjoerd G. Elias, Kim C. Aalders, K. Schreuder, Sabine Siesling, Julia E.C. van Steenhoven, J. P. J. Burgmans

Publikováno v: Annals of Surgical Oncology, 26(2), 372. Springer New York
Annals of surgical oncology, 26(2), 372-378. Springer

Background: Although the false-negative rate of the sentinel lymph node biopsy (SLNB) in breast cancer patients is 5–7%, reported regional recurrence (RR) rates after negative SLNB are much lower. Adjuvant treatment modalities probably contribute t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7b0e47086733c50dc1070c078f77db
https://dspace.library.uu.nl/handle/1874/377151

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Abstract P5-02-11: Assessment of tumor proliferation by mitotic activity index, phosphohistone H3 and Ki67 in early stage ER+/Her2- breast cancer

Autor: Joost van Gorp, Paul J. van Diest, Thijs van Dalen, A. van Leeuwen, Julia E.C. van Steenhoven, Anne Kuijer

Publikováno v: Cancer Research. 80:P5-02

Introduction: Determining expression of tumor proliferation by mitotic index or Ki67 expression is one of the strongest prognostic factors in breast cancer, but its reproducibility is not optimal. Recently, phosphohistone H3 (PHH3) was proposed as a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8fcd7785aaf40b3b21f24d86135b89a
https://doi.org/10.1158/1538-7445.sabcs19-p5-02-11

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Conventional Pathology Versus Gene Signatures for Assessing Luminal A and B Type Breast Cancers: Results of a Prospective Cohort Study

Autor: Sjoerd G. Elias, Thijs van Dalen, Emiel J. Th. Rutgers, Anne Kuijer, Joost van Gorp, Marieke E. Straver, Johanna N. H. Timmer-Bonte, Sabine Siesling, Tineke J. Smilde, Jelle Wesseling, Julia E.C. van Steenhoven, Charlotte F.J.M. Blanken, Paul J. van Diest, Alex L.T. Imholz, Peter Nieboer

Publikováno v: Genes, 9, 5
Genes
Genes, 9(5). Multidisciplinary Digital Publishing Institute (MDPI)
Genes, 9(5):261. MDPI
Genes; Volume 9; Issue 5; Pages: 261
Genes, 9

In this study, in estrogen receptor positive (ER+) early stage breast cancer patients who were considered candidates for 70-gene signature (70-GS, “MammaPrint”) use, we compared molecular subtyping (MS) based on the previously validated 80-gene s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91edc345dbbc4760cadbc9b4c69d841d
https://doi.org/10.3390/genes9050261

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