Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Julia E. Page"'
Autor:
Julia E. Page, Marina Santiago, Daniel Kahne, Suzanne Walker, Kaitlin Schaefer, Tristan W. Owens
Publikováno v:
Nature microbiology
Bacteria are encapsulated by a peptidoglycan cell wall that is essential for their survival1. During cell wall assembly, a lipid-linked disaccharide–peptide precursor called lipid II is polymerized and cross-linked to produce mature peptidoglycan.
Construction and remodeling of the bacterial peptidoglycan (PG) cell wall must be carefully coordinated with cell growth and division. Central to cell wall construction are hydrolases that cleave bonds in peptidoglycan. These enzymes also represent p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e0636b6444dfacb2883839ed7c5d239
https://doi.org/10.1101/2022.01.21.477235
https://doi.org/10.1101/2022.01.21.477235
Publikováno v:
Proc Natl Acad Sci U S A
The peptidoglycan cell wall is a macromolecular structure that encases bacteria and is essential for their survival. Proper assembly of the cell wall requires peptidoglycan synthases as well as membrane-bound cleavage enzymes that control where new p
Autor:
Julia E. Page, Suzanne Walker
Publikováno v:
Curr Opin Microbiol
The inexorable spread of resistance to clinically used drugs demands that we maintain a full pipeline of antibiotic candidates. As organisms have struggled to survive and compete over evolutionary history, they have developed the capacity to make a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf3ac0d814665f31fdabe0e65cd111f
https://europepmc.org/articles/PMC8169544/
https://europepmc.org/articles/PMC8169544/
Autor:
Marina Santiago, Julia E. Page, Kaitlin Schaefer, Tristan W. Owens, Daniel Kahne, Suzanne Walker
Bacteria are surrounded by a peptidoglycan cell wall that is essential for their survival1. During cell wall assembly, a lipid-linked disaccharide-peptide precursor called Lipid II is polymerized and crosslinked to produce mature peptidoglycan. As Li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b784a050b51b3616bcce323b420e0a88
https://doi.org/10.1101/2020.05.21.109470
https://doi.org/10.1101/2020.05.21.109470
Publikováno v:
The Journal of biological chemistry. 295(10)
Bacteria account for 1000-fold more biomass than humans. They vary widely in shape and size. The morphological diversity of bacteria is due largely to the different peptidoglycan-based cell wall structures that encase bacterial cells. Although the ba
Autor:
Samuel Thompson, Haoran Li, Julia E. Page, Catherine L. Drennan, Edward J. Brignole, Nozomi Ando, Francisco J. Asturias, JoAnne Stubbe, Martin I. McLaughlin
Publikováno v:
Biochemistry
Ribonucleotide reductases (RNRs) are responsible for all de novo biosynthesis of DNA precursors in nature by catalyzing the conversion of ribonucleotides to deoxyribonucleotides. Because of its essential role in cell division, human RNR is a target f
Autor:
Kogularamanan Suntharalingam, Yao-Rong Zheng, Julia E. Page, Timothy C. Johnstone, Fang Wang, Samuel G. Awuah, Michael T. Hemann, Wei Lin, Peter M. Bruno, Stephen J. Lippard
Publikováno v:
Journal of the American Chemical Society, vol 137, iss 8
Rhenium(V) oxo complexes of general formula [ReO(OMe)(N^N)Cl2], where N^N = 4,7-diphenyl-1,10-phenanthroline, 1, or 3,4,7,8-tetramethyl-1,10-phenanthroline, 2, effectively kill cancer cells by triggering necroptosis, a non-apoptotic form of cell deat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3591f0e2dfe493f86dcf87d6de8d7e34
https://escholarship.org/uc/item/6k27w35z
https://escholarship.org/uc/item/6k27w35z