Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Julia E. Kravchenko"'
Autor:
Julia E. Kravchenko, Peter M. Chumakov, Vladimir S. Prassolov, Stepan P. Chumakov, Elena I. Frolova
Publikováno v:
Plasmid. 63:143-149
Gene silencing based on RNA interference is widely used in fundamental research and in practical applications. However, a commonly incomplete functional suppression represents a serious drawback of this technology. We describe a series of lentiviral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e56780af331875e2c9ba292198fd7d3
https://doi.org/10.1016/j.plasmid.2009.12.003
https://doi.org/10.1016/j.plasmid.2009.12.003
Publikováno v:
Seminars in Cancer Biology. 19:32-41
The p53 tumor suppressor plays pivotal role in the organism by supervising strict compliance of individual cells to needs of the whole organisms. It has been widely accepted that p53 acts in response to stresses and abnormalities in cell physiology b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9f5c196e7a027628fcbb311fa7fcb8
https://doi.org/10.1016/j.semcancer.2008.11.005
https://doi.org/10.1016/j.semcancer.2008.11.005
Autor:
V. S. Prasolov, Julia E. Kravchenko, P. M. Chumakov, G. V. Ilyinskaya, S. P. Chumakov, Elena I. Frolova
Publikováno v:
Molecular Biology. 42:894-900
An enzymatic assay system was developed to quantify the distribution of recombinant proteins over various cell structures. The system takes advantage of α-complementation of β-galactosidase. The large ω fragment of β-galactosidase is expressed in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74add7a8a637bfd16f574a16c4cd0570
https://doi.org/10.1134/s0026893308060095
https://doi.org/10.1134/s0026893308060095
Autor:
Marina A. Afanasyeva, Subir Biswas, Julia E. Kravchenko, Alisa M. Muratova, A. M. Schwartz, Nikita A. Mitkin, Arindam Bhattacharyya, Dmitry V. Kuprash, Dmitry V. Kochetkov, Christina D. Hook
Publikováno v:
Scientific Reports
Elevated expression of chemokine receptors in tumors has been reported in many instances and is related to a number of survival advantages for tumor cells including abnormal activation of prosurvival intracellular pathways. In this work we demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c8ec34d7e47abf7caefa6e2b118cc72
Autor:
Elena N. Pugacheva, Julia E. Kravchenko, P. M. Chumakov, Arnold J. Levine, Boris P. Kopnin, Alexey V. Ivanov
Publikováno v:
Oncogene. 21:4595-4600
Mutated forms of p53 are often expressed in a variety of human tumors. In addition to loss of function of the p53 tumor suppressor, mutant p53s contribute to malignant process by acquisition of novel functions that enhance transformed properties of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536cc896ddbd0811222d17db5ea4a54f
https://doi.org/10.1038/sj.onc.1205704
https://doi.org/10.1038/sj.onc.1205704
Autor:
D. V. Kochetkov, Evguenia Strom, Julia E. Kravchenko, Andrei V. Gudkov, Elena I. Frolova, Elena Feinstein, P. M. Chumakov, I. Kovriga, Pavel G. Komarov, G. V. Ilyinskaya, L. S. Agapova
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(17)
Identification of unique features of cancer cells is important for defining specific and efficient therapeutic targets. Mutant p53 is present in nearly half of all cancer cases, forming a promising target for pharmacological reactivation. In addition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d4cc2bdb612d1eecdf1cceb06f5667
https://pubmed.ncbi.nlm.nih.gov/18424558
https://pubmed.ncbi.nlm.nih.gov/18424558
Autor:
P. M. Chumakov, L. S. Agapova, Andrei V. Budanov, Anna Sablina, G. V. Ilyinskaya, Julia E. Kravchenko
It is widely accepted that the p53 tumor suppressor restricts abnormal cells by induction of growth arrest or by triggering apoptosis. Here we show that, in addition, p53 protects the genome from oxidation by reactive oxygen species (ROS), a major ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f726951db1fef12ffeaac965f46c486
https://europepmc.org/articles/PMC2637821/
https://europepmc.org/articles/PMC2637821/
Androgen regulates apoptosis induced by TNFR family ligands via multiple signaling pathways in LNCaP
Autor:
Natalya V. Guseva, Agshin F. Taghiyev, Rebecca A Glover, P. M. Chumakov, Julia E. Kravchenko, Oskar W. Rokhlin, Michael B. Cohen
It has been suggested in many studies that combined treatment with chemotherapeutic agents and apoptosis-inducing ligands belonging to TNFR family is a more effective strategy for cancer treatment. However, the role of androgen regulation of TNFR fam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9204d4dc0ce30cd9deebe9a0fdae1d
https://europepmc.org/articles/PMC1361275/
https://europepmc.org/articles/PMC1361275/
Publikováno v:
Nature. 436(7051)
Transcription of eukaryotic genes is performed by three nuclear RNA polymerases, of which RNA polymerase II is thought to be solely responsible for the synthesis of messenger RNAs. Here we show that transcription of some mRNAs in humans and rodents i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa17d6c1a9d2dea8f01f7394cbbeebe
https://pubmed.ncbi.nlm.nih.gov/25297440
https://pubmed.ncbi.nlm.nih.gov/25297440