Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Julia E. Blower"'
Autor:
Afnan M. F. Darwesh, Cinzia Imberti, Joanna J. Bartnicka, Fahad Al-Salemee, Julia E. Blower, Alex Rigby, Jayanta Bordoloi, Alex Griffiths, Michelle T. Ma, Philip J. Blower
Publikováno v:
Molecules, Vol 28, Iss 20, p 7217 (2023)
KP46 (tris(hydroxyquinolinato)gallium(III)) is an experimental, orally administered anticancer drug. Its absorption, delivery to tumours, and mode of action are poorly understood. We aimed to gain insight into these issues using gallium-67 and galliu
Externí odkaz:
https://doaj.org/article/781d2e5334fb4f919bb9b6a45b0024d7
Autor:
Francis Man, Alexander Koers, Panagiotis Karagiannis, Debra H. Josephs, Heather J. Bax, Amy E. Gilbert, Tihomir S. Dodev, Silvia Mele, Giulia Chiaruttini, Silvia Crescioli, Jitesh Chauhan, Julia E. Blower, Margaret S. Cooper, James Spicer, Sophia N. Karagiannis, Philip J. Blower
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
IgE antibodies elicit powerful immune responses, recruiting effector cells to tumors more efficiently and with greater cytotoxicity than IgG antibodies. Consequently, IgE antibodies are a promising alternative to conventional IgG-based therapies in o
Externí odkaz:
https://doaj.org/article/59a0d8fd7d8e4872844a46ea0fa1a73b
Autor:
Julia E. Blower, Jayanta K. Bordoloi, Alex Rigby, Matthew Farleigh, Jana Kim, Hugh O'Brien, Jonathan Jackson, Constantinos Poyiatzis, James Bezer, Kavitha Sunassee, Philip J. Blower, Lefteris Livieratos
Publikováno v:
Frontiers in Physics, Vol 8 (2020)
Background: Multi-tracer PET/SPECT imaging enables different modality tracers to be present simultaneously, allowing multiple physiological processes to be imaged in the same subject, within a short time-frame. Fluorine-18 and technetium-99m, two com
Externí odkaz:
https://doaj.org/article/852703950763404891786400377a7ca0
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 2, Iss 1, Pp 1-10 (2017)
Abstract Background Nitrogen-13 has a 10-min half-life which places time constraints on the complexity of viable synthetic methods for its incorporation into PET imaging agents. In exploring ways to overcome this limitation, we have used the Ugi reac
Externí odkaz:
https://doaj.org/article/ed594e2a1dab419e9c1b90d9d9133214
Autor:
Cinzia Imberti, Pierre Adumeau, Julia E. Blower, Fahad Al Salemee, Julia Baguña Torres, Jason S. Lewis, Brian M. Zeglis, Samantha Y. A. Terry, Philip J. Blower
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1496 (2020)
Pretargeting is widely explored in immunoPET as a strategy to reduce radiation exposure of non-target organs and allow the use of short-lived radionuclides that would not otherwise be compatible with the slow pharmacokinetic profiles of antibodies. H
Externí odkaz:
https://doaj.org/article/673bc39c55754eba9f9d9ba70b77742e
Autor:
Johanna Pruller, Truc Thuy Pham, Julia E. Blower, Putthiporn Charoenphun, Alessia Volpe, Kavitha Sunassee, Gregory E. D. Mullen, Philip J. Blower, Richard A. G. Smith, Michelle T. Ma
Publikováno v:
RSC Chemical Biology. 4:65-73
An indium-111-labelled peptide binds to myeloma cells, enabling SPECT imaging of myeloma cell accumulation in lungs after intravenous administration. This is the first report of a radiolabelled cell-membrane binding peptide for cell tracking.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::070d08a57bacd15edc33847edef5af3b
https://doi.org/10.1039/d2cb00164k
https://doi.org/10.1039/d2cb00164k
Publikováno v:
Nuclear medicine and biology
Introduction Thallium-201 is a radionuclide that has previously been used clinically for myocardial perfusion scintigraphy. Although in this role it has now been largely replaced by technetium-99 m radiopharmaceuticals, thallium-201 remains attractiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c131b3f1c3f84b390c95ebfe26a2f58a
http://europepmc.org/articles/PMC7610824
http://europepmc.org/articles/PMC7610824
Autor:
George Firth, Julia E. Blower, Joanna J. Bartnicka, Aishwarya Mishra, Aidan M. Michaels, Alex Rigby, Afnan Darwesh, Fahad Al-Salemee, Philip J. Blower
Publikováno v:
RSC chemical biology. 3(5)
Several specific metallic elements must be present in the human body to maintain health and function. Maintaining the correct quantity (from trace to bulk) and location at the cell and tissue level is essential. The study of the biological role of me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404eb370665ee8e59590b0266bd3ddd4
https://pubmed.ncbi.nlm.nih.gov/35656481
https://pubmed.ncbi.nlm.nih.gov/35656481
Autor:
Matthew Farleigh, Julia E. Blower, Jonathan Jackson, Jana Kim, Lefteris Livieratos, Kavitha Sunassee, James Bezer, Jayanta Bordoloi, Hugh O'Brien, Constantinos Poyiatzis, Philip J. Blower, Alex Rigby
Publikováno v:
Frontiers in physics
Blower, J E, Bordoloi, J K, Rigby, A, Farleigh, M, Kim, J, O'Brien, H, Jackson, J, Poyiatzis, C, Bezer, J, Sunassee, K, Blower, P J & Livieratos, L 2020, ' Protocols for Dual Tracer PET/SPECT Preclinical Imaging ', Frontiers in Physics, vol. 8, 126 . https://doi.org/10.3389/fphy.2020.00126
Frontiers in Physics, Vol 8 (2020)
Blower, J E, Bordoloi, J K, Rigby, A, Farleigh, M, Kim, J, O'Brien, H, Jackson, J, Poyiatzis, C, Bezer, J, Sunassee, K, Blower, P J & Livieratos, L 2020, ' Protocols for Dual Tracer PET/SPECT Preclinical Imaging ', Frontiers in Physics, vol. 8, 126 . https://doi.org/10.3389/fphy.2020.00126
Frontiers in Physics, Vol 8 (2020)
Background: Multi-tracer PET/SPECT imaging enables different modality tracers to be present simultaneously, allowing multiple physiological processes to be imaged in the same subject, within a short time-frame. Fluorine-18 and technetium-99m, two com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae94933812abf0888535a796af21d117
https://pubmed.ncbi.nlm.nih.gov/34113608
https://pubmed.ncbi.nlm.nih.gov/34113608
Publikováno v:
Blower, J, Ma, M, Al-Salemee, F & Gee, T 2021, ' The Hantzsch reaction for nitrogen-13 PET: preparation of [ 13 N]nifedipine and derivatives ', Chemical communications (Cambridge, England), vol. 57, no. 40, pp. 4962-4965 . https://doi.org/10.1039/d1cc00495f
Nitrogen-13 is an attractive but under-used PET radionuclide for labelling molecules of biological and pharmaceutical interest, complementing other PET radionuclides. Its short half-life (t1/2 = 9.97 min) imposes synthetic challenges, but we have exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42177d96ee0d1b5422f5c392a58ce519
https://kclpure.kcl.ac.uk/ws/files/151199985/ChemComm_Nifedipine_March_2021_corrections_FINAL_4pg.pdf
https://kclpure.kcl.ac.uk/ws/files/151199985/ChemComm_Nifedipine_March_2021_corrections_FINAL_4pg.pdf
