Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Julia E Sero"'
Publikováno v:
eLife, Vol 13 (2024)
The canonical NF-κB transcription factor RELA is a master regulator of immune and stress responses and is upregulated in pancreatic ductal adenocardinoma (PDAC) tumours. In this study, we characterised previously unexplored endogenous RELA-GFP dynam
Externí odkaz:
https://doaj.org/article/026c08f779a245469dc5d95cd359a962
Autor:
Julia E Sero, Heba Zuhair Sailem, Rico Chandra Ardy, Hannah Almuttaqi, Tongli Zhang, Chris Bakal
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 3, Pp 1-16 (2015)
Abstract Although a great deal is known about the signaling events that promote nuclear translocation of NF‐κB, how cellular biophysics and the microenvironment might regulate the dynamics of this pathway is poorly understood. In this study, we us
Externí odkaz:
https://doaj.org/article/9e159c8842f1468e860ed1768eef723e
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28303 (2011)
Physical interactions between cells and the extracellular matrix (ECM) guide directional migration by spatially controlling where cells form focal adhesions (FAs), which in turn regulate the extension of motile processes. Here we show that physical c
Externí odkaz:
https://doaj.org/article/ae8282e2d4c24500aa025cedd4a2f9f7
The canonical NF-κB transcription factor RELA is a master regulator of immune and stress responses and is upregulated in PDAC tumours. Here, we characterised previously unknown endogenous RELA-GFP dynamics in PDAC cell lines by live single cell imag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7ea02b6878e6423ced5e817e2c20f5e
https://doi.org/10.1101/2022.01.19.476961
https://doi.org/10.1101/2022.01.19.476961
Autor:
Julia E, Sero, Molly M, Stevens
Publikováno v:
Advances in experimental medicine and biology. 1295
Nanoneedles, defined as high aspect ratio structures with tip diameters of 5 to approximately 500 nm, are uniquely able to interface with the interior of living cells. Their nanoscale dimensions mean that they are able to penetrate the plasma membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::717c6dd630bd63f5e41997e44313bc60
https://pubmed.ncbi.nlm.nih.gov/33543461
https://pubmed.ncbi.nlm.nih.gov/33543461
Autor:
Molly M. Stevens, Julia E. Sero
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030581732
Nanoneedles, defined as high aspect ratio structures with tip diameters of 5 to approximately 500 nm, are uniquely able to interface with the interior of living cells. Their nanoscale dimensions mean that they are able to penetrate the plasma membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60c1b41f8e15743bb1467abc2a1d951d
https://doi.org/10.1007/978-3-030-58174-9_9
https://doi.org/10.1007/978-3-030-58174-9_9
Autor:
Stacey C. Skaalure, Stephanie A. Maynard, Isaac J. Pence, Charlotte Lee-Reeves, Amy Gelmi, Thomas E. Whittaker, Molly M. Stevens, Julia E. Sero
Publikováno v:
Maynard, S, Gelmi, A, Skaalure, S, Pence, I, Lee-Reeves, C, Sero, J, Whittaker, T & Stevens, M 2020, ' Nanoscale Molecular Quantification of Stem Cell−Hydrogel Interactions ', ACS Nano, vol. 14, pp. 17321-17332 . https://doi.org/10.1021/acsnano.0c07428
ACS Nano
ACS Nano
A common approach to tailoring synthetic hydrogels for regenerative medicine applications involves incorporating RGD cell adhesion peptides, yet assessing the cellular response to engineered microenvironments at the nanoscale remains challenging. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::804260781c70d3da4526b407e3387a01
https://purehost.bath.ac.uk/ws/files/226611337/Maynard_ACS_Nano_2020.pdf
https://purehost.bath.ac.uk/ws/files/226611337/Maynard_ACS_Nano_2020.pdf
Autor:
Michele Becce, Molly M. Stevens, Hyejeong Seong, Julia E. Sero, Stuart G. Higgins, Spencer W. Crowder, A.C. Moore, Jelle Penders, James P. K. Armstrong
Publikováno v:
Seong, H, Higgins, S G, Penders, J, Armstrong, J P K, Crowder, S W, Moore, A C, Sero, J E, Becce, M & Stevens, M M 2020, ' Size-Tunable Nanoneedle Arrays for Influencing Stem Cell Morphology, Gene Expression, and Nuclear Membrane Curvature ', ACS Nano, vol. 14, no. 5, pp. 5371-5381 . https://doi.org/10.1021/acsnano.9b08689
ACS Nano
ACS Nano
High-aspect-ratio nanostructures have emerged as versatile platforms for intracellular sensing and biomolecule delivery. Here, we present a microfabrication approach in which a combination of reactive ion etching protocols were used to produce high-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6e53c766c9e0ae8d3e2c51229e8a10
https://research-information.bris.ac.uk/ws/files/308458644/Full_text_PDF_final_published_version_.pdf
https://research-information.bris.ac.uk/ws/files/308458644/Full_text_PDF_final_published_version_.pdf
Publikováno v:
Communications in Computer and Information Science ISBN: 9783030527907
MIUA
MIUA
Accurate segmentation of cellular structures is critical for automating the analysis of microscopy data. Advances in deep learning have facilitated extensive improvements in semantic image segmentation. In particular, U-Net, a model specifically deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6759daa5b9ced0431f7c14123932db60
https://doi.org/10.1007/978-3-030-52791-4_13
https://doi.org/10.1007/978-3-030-52791-4_13
Autor:
Chris Bakal, Julia E. Sero
Publikováno v:
Sero, J & Bakal, C 2019, ' The forces of cancer ', Philosophical Transactions of the Royal Society B: Biological Sciences, vol. 374, no. 1779, 20190103, pp. 1-3 . https://doi.org/10.1098/rstb.2019.0103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae90ec2e67d078e8067c33057a8aee3
https://europepmc.org/articles/PMC6627019/
https://europepmc.org/articles/PMC6627019/