Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Julia E, Brittain"'
Autor:
Kenneth I Ataga, Julia E Brittain, Payal Desai, Ryan May, Susan Jones, John Delaney, Dell Strayhorn, Alan Hinderliter, Nigel S Key
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29786 (2012)
The contribution of hypercoagulability to the pathophysiology of sickle cell disease (SCD) remains poorly defined. We sought to evaluate the association of markers of coagulation and platelet activation with specific clinical complications and labora
Externí odkaz:
https://doaj.org/article/62bc85a326de4a0a9d5477557259aa98
Autor:
Ha Won Kim, Matthew Crowe, Weiqin Chen, Orishebawo Popoola, Brian K. Stansfield, Tyler W. Benson, Yan Gao, Yao Liang Tang, David W. Stepp, James G. Wilson, Tapan K. Chatterjee, Vladimir Y. Bogdanov, Neal L. Weintraub, Julia E. Brittain, Krystal Archer, Charlotte Greenway, James D. Mintz, Daniel S. Weintraub, Joel Joseph, Ajay Pillai, Nicole K.H. Yiew
Publikováno v:
Molecular and cellular endocrinology
Objective Inflammation in adipose tissues in obesity promotes insulin resistance and metabolic disease. The Duffy antigen receptor for chemokines (DARC) is a promiscuous non-signaling receptor expressed on erythrocytes and other cell types that modul
Autor:
Nigel S. Key, Adam McDonald, Ciprian B. Anea, Payal Desai, Julia E. Brittain, Leslie V. Parise, Kenneth I. Ataga, John J Delaney, Stephen W. Looney
Publikováno v:
American Journal of Hematology. 93:E99-E101
Autor:
Greer Falls, Itia A. Lee, Julia E. Brittain, Matthew Lyon, Amidat Adeyemi, Ciprian B. Anea, Abdullah Kutlar, Joyce Gonzales
Publikováno v:
American Journal of Hematology
A growing body of evidence suggests a role for platelets in sickle cell disease (SCD). Despite the proinflammatory, occlusive nature of platelets, a role for platelets in acute chest syndrome (ACS), however, remains understudied. To provide evidence
Autor:
Víctor M. Blanco, Wilson Tong, Robert Sturm, Abigail Peairs, Danielle Coyle, Andra L. Blomkalns, W. Sean Davidson, Tyler W. Benson, Bruce J. Aronow, Theodosia A. Kalfa, Stephen Haigh, David Manka, Mary B. Palascak, Dusten Unruh, Ryan D. Keil, Ramprasad Srinivasan, David J. Fulton, David Y. Hui, Vladimir Y. Bogdanov, Julia E. Brittain, Tapan K. Chatterjee, Robert S. Franco, Neal L. Weintraub, Neil Batra
Publikováno v:
Circulation. 132:1898-1908
Background— High-fat diet (HFD) promotes endothelial dysfunction and proinflammatory monocyte activation, which contribute to atherosclerosis in obesity. We investigated whether HFD also induces the dysfunction of red blood cells (RBCs), which serv
Autor:
Benjamin Vieira, Julia E. Brittain, Sarah Sturtevant, Sriram Krishnamoorthy, Dipti Gupta, Timothy Thullen, Levi Makala, Huo Li, Biaoru Li, David R. Light, Betty S. Pace, Ivan Stone, Nancy Moore, William E. Hobbs
Publikováno v:
JCI insight. 2(20)
Sickle cell disease (SCD) results from a point mutation in the β-globin gene forming hemoglobin S (HbS), which polymerizes in deoxygenated erythrocytes, triggering recurrent painful vaso-occlusive crises and chronic hemolytic anemia. Reactivation of
Autor:
Adam McDonald, Nigel S. Key, Kenneth I. Ataga, Douglas R. Wilson, Rosalie Dominik, Leslie V. Parise, Payal Desai, Julia E. Brittain, Susan Jones
Publikováno v:
Thrombosis Research. 132:341-345
Abstract 2102 Background: Despite the abundant laboratory evidence of platelet activation and inflammation in sickle cell disease (SCD), the contribution of these changes to the pathogenesis of SCD remains uncertain. Patients with SCD exhibit increas
Autor:
Sina Haeri, D. Leann Long, Kim A. Boggess, Arthur M. Baker, Padmashree Chaudhury Woodham, Carlos A. Camargo, Alison M. Stuebe, Julia E. Brittain
Publikováno v:
Hypertension. 58:1120-1125
Recent studies have shown that low serum 25-hydroxyvitamin D (25[OH]D) level is a risk factor for preeclampsia. The clinical significance of in vitro findings that vitamin D regulates vascular endothelial growth factor production is unclear. We sough
Autor:
Ryan May, Kenneth I. Ataga, Nigel S. Key, Dell Strayhorn, Payal Desai, Julia E. Brittain, Rupa Redding-Lallinger, John J Delaney, Susan Jones, Eugene P. Orringer
Publikováno v:
British Journal of Haematology. 152:485-491
The pathophysiology of pulmonary hypertension (PHT) in sickle cell disease (SCD) is probably multifactorial. Soluble fms-like tyrosine kinase-1 (sFLT-1) is a member of the vascular endothelial growth factor receptor (VEGFR) family. By adhering to and
Autor:
Dell Strayhorn, Soheir S. Adam, Susan Jones, Eugene P. Orringer, Kenneth I. Ataga, Patrick H. Nachman, Dominic Moore, Julia E. Brittain, Rupa Redding-Lallinger, Ben Hulkower
Publikováno v:
European Journal of Haematology. 85:257-263
Background Pulmonary hypertension (PHT) is reported to be associated with measures of renal function in patients with sickle cell disease (SCD). The purpose of this exploratory study was to determine the relationship between albuminuria and both clin