Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Julia D. Mackay"'
Autor:
Radhika C. Desai, Hyo Jin Kim, Julia D. Mackay, Weijun Feng, Randall J. Mrsny, Lisa Song, Linh P. Nyugen, Nicole C. Fay, Mahmood Tahir, Sally Postlethwaite, Apurva Chandalia, Baby Periyanayaki Muthusamy, Keyi Liu, Michael P. Coyle, Olson Charles, Elbert Seto, Tom Hunter, Khushdeep Mangat, Alistair Taverner, Minji Seung, Aatif Alam, Maziyar Saberi
Publikováno v:
J Immunol
IL-10 is a potent anti-inflammatory cytokine capable of suppressing a number of proinflammatory signals associated with intestinal inflammatory diseases, such as ulcerative colitis and Crohn's disease. Clinical use of human IL-10 (hIL-10) has been li
Autor:
Julia D. Mackay, Ruiying Li, Alistair Taverner, Randall J. Mrsny, Floriane Laurent, Paul De Bank
Publikováno v:
Pharmaceutics
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1171, p 1171 (2021)
Volume 13
Issue 8
Pharmaceutics, Vol 13, Iss 1171, p 1171 (2021)
The low permeability of nanoparticles (NPs) across the intestinal epithelium remains a major challenge for their application of delivering macromolecular therapeutic agents via the oral route. Previous studies have demonstrated the epithelial transcy
Autor:
Randall J. Mrsny, Alistair Taverner, Weijun Feng, Keyi Liu, Tom Hunter, Khushdeep Mangat, Elbert Seto, Sally Postlethwaite, Lisa Song, Apurva Chandalia, Mazi Saberi, Floriane Laurent, Aatif Alam, Minji Seung, Julia D. Mackay
Publikováno v:
Tissue Barriers
Cholix (Chx) is expressed by the intestinal pathogen Vibrio cholerae as a single chain of 634 amino acids (~70.7 kDa protein) that folds into three distinct domains, with elements of the second and third domains being involved in accessing the cytopl
Autor:
Alexey Zozulya, Jean M. H. van den Elsen, D. I. Svergun, Susan J. Crennell, Abhishek Upadhyay, Julia D. Mackay, Elizabeth A. Clark, Stefan Bagby
Publikováno v:
Molecular Immunology
Molecular immunology 48, 452-462 (2011). doi:10.1016/j.molimm.2010.09.017
Molecular immunology 48, 452-462 (2011). doi:10.1016/j.molimm.2010.09.017
The structure of the complement-binding domain of Staphylococcus aureus protein Sbi (Sbi-IV) in complex with ligand C3d is presented. The 1.7 A resolution structure reveals the molecular details of the recognition of thioester-containing fragment C3d
Publikováno v:
The Journal of Immunology. 184:1946-1955
We recently characterized an interaction between the Staphylococcus aureus immune evasion molecule Staphylococcus aureus binder of Ig (Sbi) and complement C3, an interaction mediated primarily through the binding of C3d(g) to Sbi domain IV. Events re
Autor:
Jean M. H. van den Elsen, Tony D. James, Julia D. Mackay, J. Grant Buchanan, John S. Fossey, Marta P. Pereira Morais, Savroop K. Bhamra
Publikováno v:
PROTEOMICS. 10:48-58
The incorporation of the specialized carbohydrate affinity ligand methacrylamido phenylboronic acid in polyacrylamide gels for SDS-PAGE analysis has been successful for the separation of carbohydrates and has here been adapted for the analysis of pos