Role of macrophages in age-related oxidative stress and lipofuscin accumulation in mice

Autor: Carmen Vida, Irene Martínez de Toda, Julia Cruces, Antonio Garrido, Mónica Gonzalez-Sanchez, Mónica De la Fuente

Publikováno v: Redox Biology, Vol 12, Iss , Pp 423-437 (2017)

The age-related changes in the immune functions (immunosenescence) may be mediated by an increase of oxidative stress and damage affecting leukocytes. Although the “oxidation-inflammation” theory of aging proposes that phagocytes are the main imm

Externí odkaz: https://doaj.org/article/9ebc61a2cf7347a5899d8e456cdc3997

Social Environment Ameliorates Behavioral and Immune Impairments in Tyrosine Hydroxylase Haploinsufficient Female Mice

Autor: F de Pablo, Antonio Garrido, Mónica De la Fuente, Catalina Hernández-Sánchez, Noemí Ceprián, Julia Cruces

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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19 p.-3 fig.-3 tab.
The social environment can influence the functional capacity of nervous and immune systems, and consequently the state of health, especially in aged individuals. Adult female tyrosine hydroxylase haploinsufficient (TH-HZ) mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0048641981e4b3212594d838308cc4f9
https://doi.org/10.1007/s11481-020-09947-2

Social environment improves immune function and redox state in several organs from prematurely aging female mice and increases their lifespan

Autor: I. Corpas, Noemí Ceprián, Antonio Garrido, Jesús A.F. Tresguerres, Mónica De la Fuente, Julia Cruces

Publikováno v: Biogerontology. 20:49-69

Aging is associated with a chronic oxidative stress (increase of oxidants and decrease of antioxidants), which contributes to immunosenescence and therefore shorter longevity. Nevertheless, a positive social network has been related to the adequate m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc7f76e392c1dbdb897d12fe323bea32
https://doi.org/10.1007/s10522-018-9774-4

Premature aging in behavior and immune functions in tyrosine hydroxylase haploinsufficient female mice. A longitudinal study

Autor: Noemí Ceprián, Catalina Hernández-Sánchez, Julia Cruces, Antonio Garrido, M. De la Fuente

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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16 p.-6 fig.-3 tab.
This work was supported by FIS grants (PI15/01787) from theISCIII-FEDER of the European Union, the Research group of UCM(910379), Red Telemática de Investigación Cooperativa en Envejecimiento y Fragilidad (RETICEF) (RD12/00

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890c1e799e525caa79bb7800ec62818c
https://doi.org/10.1016/j.bbi.2018.01.003

Oxidative-Inflammatory Stress in Immune Cells from Adult Mice with Premature Aging

Autor: Mónica De la Fuente, Antonio Garrido, Elena Vara, Noemí Ceprián, Julia Cruces

Publikováno v: International Journal of Molecular Sciences
Volume 20
Issue 3
E-Prints Complutense. Archivo Institucional de la UCM
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E-Prints Complutense: Archivo Institucional de la UCM
Universidad Complutense de Madrid
International Journal of Molecular Sciences, Vol 20, Iss 3, p 769 (2019)

Oxidative and inflammatory stresses are closely related processes, which contribute to age-associated impairments that affect the regulatory systems such as the immune system and its immunosenescence. Therefore, the aim of this work was to confirm wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fa9d998f83979877c9ce69a6f77faf7
https://pubmed.ncbi.nlm.nih.gov/30759732