Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Julia Cianci"'
Publikováno v:
Molecules, Vol 9, Iss 6, Pp 427-439 (2004)
The preparation and characterization by LCMS of a library of 55 fluorescence- quenched peptides is described. The peptides bear a terminal anthranilamide fluorophore and a penultimate 2,4-dinitrophenyl-L-lysine quencher, and will be used to probe the
Externí odkaz:
https://doaj.org/article/d98b5b2a1c0a4b318697dd245f700f1b
Autor:
Julia Cianci
Publikováno v:
Archives and Manuscripts. 41:33-43
The synthesis and testing of thousands of chemical compounds is an essential process in the development of small molecule drug therapies. Over time, even a small research group can generate tens of thousands of compounds and a vast amount of data tha
Autor:
Dharam Paul, Robert W. Gable, Jonathan B. Baell, Julia Cianci, Jorgen Alvar Mould, Andrew John Harvey, Bernard L. Flynn
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:2055-2061
Chalcone derivatives of the natural product khellinone were synthesised and screened for bioactivity against the voltage-gated potassium channel Kv1.3. X-ray crystallography was employed to investigate relationships between the structure and function
Autor:
Robert N. Pike, Justin P. Ludeman, Bernard Le Bonniec, Julia Cianci, Peter J. Duggan, James C. Whisstock, Stephen P. Bottomley, Karen Maree Bromfield
Publikováno v:
Monash University
Factor Xa is a central protease in the coagulation cascade and the target for many anticoagulant compounds currently under development. The preferences of the enzyme for substrates incorporating residues N-terminal to the cleavage site (P1, P2, etc.)
Autor:
Richard Hufton, Jianmin Duan, Carlie T. Gannon, Tyrone Pieter Jeynes, Barbara Frey, George Kukolj, Alistair George Draffan, Rosliana Halim, Van T. T. Nguyen, Benjamin H. Fraser, Bruno Simoneau, Melinda J. Pryor, Edward M. Tyndall, Lilly Michael John, Kate Porter, Michael Harding, Silas Bond, Julia Cianci, Brett Pool, Simon P. Tucker, Bo Lin, Danielle Tilmanis, Angela Luttick, Saba Jahangiri, Veronika Wirth, Richard Bethell, Craig J. Morton
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(21)
Previous investigations identified 2′-C-Me-branched ribo-C-nucleoside adenosine analogues, 1, which contains a pyrrolo[2,1-f][1,2,4]triazin-4-amine heterocyclic base, and 2, which contains an imidazo[2,1-f][1,2,4]triazin-4-amine heterocyclic base a
Publikováno v:
Tetrahedron Letters. 48:5973-5975
Incorporation of the extremely hindered amino acid N-benzylaminoisobutyric acid into dipeptides under microwave irradiation with commercial zinc dust is described. A comparative survey of various methodologies for hindered peptide couplings was under
Autor:
Graves, Stephen R., Islam, Aminul, Webb, Lawrence D., Marsh, Ian, Plain, Karren, Westman, Mark, Conlan, Xavier A., Carbis, Rodney, Toman, Rudolf, Stenos, John
Publikováno v:
Vaccines; Sep2022, Vol. 10 Issue 9, p1393-N.PAG, 12p
Publikováno v:
Molecules; Jun2004, Vol. 9 Issue 6, p427-439, 13p
Autor:
Bathroom Readers' Institute
PGWUncle John's taking the plunge... into the Great White North! RaincoastHey, Canada! Uncle John salutes you!For 25 years, Uncle John's Bathroom Reader has been wildly popular in Canada, so we decided to dedicate an entire edition to our friends in
Autor:
Lesley Riley
Lesley Riley is one of the inventors of Transfer Art Paper and an unparalleled expert on how to use TAP for maximum creative effect. She'll teach you how to create unique fabric images from photographs that stay vibrant and colorfast, even after wash