Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Julia C. Shelton"'
Autor:
Jing Xu, Junyao Yang, Jian Chen, Xiaoli Zhang, Yuanhao Wu, Alister Hart, Agata Nyga, Julia C. Shelton
Publikováno v:
Particle and Fibre Toxicology, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background The toxicity of released metallic particles generated in metal-on-metal (MoM) total hip arthroplasty (THA) using cobalt chromium (CoCr) has raised concerns regarding their safety amongst both surgeons and the public. Soft tissue c
Externí odkaz:
https://doaj.org/article/dfe6ecd58a6840c187b1e83ff1a412ea
Publikováno v:
Journal of Biomechanical Science and Engineering, Vol 4, Iss 4, Pp 510-517 (2009)
Intermittent pattern of mechanical stimulation has been demonstrated to possess different regulatory effects on cell metabolism in many connective tissues, but little is known about tenocyte responses. A previous study has shown that the application
Externí odkaz:
https://doaj.org/article/9d26b3b419c349d3809fbe328d66092b
Autor:
Julia C. Shelton, Yuanhao Wu, Jing Xu, Jian Chen, Xiaoli Zhang, Junyao Yang, Agata Nyga, Alister Hart
Publikováno v:
Particle and Fibre Toxicology
Particle and Fibre Toxicology, Vol 17, Iss 1, Pp 1-13 (2020)
Particle and Fibre Toxicology, Vol 17, Iss 1, Pp 1-13 (2020)
Background The toxicity of released metallic particles generated in metal-on-metal (MoM) total hip arthroplasty (THA) using cobalt chromium (CoCr) has raised concerns regarding their safety amongst both surgeons and the public. Soft tissue changes su
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
This study used isolated human tenocytes to test the hypothesis that cyclic mechanical strain directly stimulates primary cilia disassembly, and to elucidate the mechanisms involved. Cells were seeded onto flexible membranes and strained at 0–3%; 1
Autor:
Halimat Y. Raji, Julia C. Shelton
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 107:138-148
The head-neck taper junction has been widely reported to corrode leading to adverse tissue reactions. Taper corrosion is a poorly understood phenomenon but has been associated with oxide layer damage and ingress of corrosive physiological fluids. Mic
Publikováno v:
Biotechnology and Bioengineering. 114:1614-1625
Articular cartilage with its inherently poor capacity for self-regeneration represents a primary target for tissue engineering strategies, with approaches focusing on the in vitro generation of neo-cartilage using chondrocyte-seeded 3D scaffolds subj
Autor:
Clare L. Thompson, Huan Meng, Julia C. Shelton, Martin M. Knight, Han Wu, Zhao Wang, Song Liu, Shengyuan Liu, Su Fu
Publikováno v:
Biochemical and Biophysical Research Communications. 555:213
Autor:
Danielle de Villiers, Julia C. Shelton
Publikováno v:
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. 230:398-405
Simulation of wear in total hip replacements has been recognised as an important factor in determining the likelihood of clinical success. However, accurate measurement of wear can be problematic with factors such as number and morphology of wear par
Publikováno v:
Clinical Biomechanics. 79:104924
Background Cobalt ions from some orthopaedic implants induce a dose-dependent cytotoxic and pro-inflammatory response. Recent studies show that sub-toxic levels of cobalt influence actin organisation regulating fibroblasts and macrophages behaviour.
Publikováno v:
Clinical Biomechanics. 79:104972
BackgroundMechanical conditioning has been widely used to attempt to enhance chondrocyte metabolism for the evolution of functionally competent cartilage. However, although upregulation of proteoglycans have been reported through the application of u