Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Julia C. Frei"'
Publikováno v:
Virology
Antibodies (Abs) recognizing the Dengue virus (DENV) E dimer epitope (EDE) that potently neutralize all DENV serotypes are promising templates for vaccine design. As an important feature for some Abs is their bivalency, we sought to define the role a
Synthetic Antibodies with a Human Framework That Protect Mice from Lethal Sudan Ebolavirus Challenge
Autor:
Jayne F. Koellhoffer, Hua Long, Julia C. Frei, Nina Liu, Kaajal Nagar, Sachdev S. Sidhu, Jonathan R. Lai, Wei Ye, John M. Dye, Samantha E. Zak, Guohua Pan, Gang Chen, Kartik Chandran
Publikováno v:
ACS Chemical Biology
The ebolaviruses cause severe and rapidly progressing hemorrhagic fever. There are five ebolavirus species; although much is known about Zaire ebolavirus (EBOV) and its neutralization by antibodies, little is known about Sudan ebolavirus (SUDV), whic
Autor:
Julia C. Frei, Jonathan R. Lai
Publikováno v:
Methods in enzymology. 580
Phage display is an in vitro selection technique that allows for the rapid isolation of proteins with desired properties including increased affinity, specificity, stability, and new enzymatic activity. The power of phage display relies on the phenot
Autor:
Kartik Chandran, Julia C. Frei, Russell R. Bakken, Samantha E. Zak, Elisabeth K. Nyakatura, John M. Dye, Jonathan R. Lai
Publikováno v:
Scientific Reports
Filoviruses (Ebola and Marburg) cause severe hemorrhagic fever. There are five species of ebolavirus; among these, the Ebola (Zaire) and Sudan viruses (EBOV and SUDV, respectively) are highly pathogenic and have both caused recurring, large outbreaks
Autor:
M. Javad Aman, Hong Vu, Robin Douglas, Sergey Shulenin, John M. Dye, Marnie L. Fusco, Sonal J. Patel, Andrew S. Herbert, Jonathan R. Lai, Marcus M. Karim, Erica Ollmann Saphire, Katie A. Howell, Bronwyn M. Gunn, Kelly L. Warfield, Ariel S. Wirchnianski, Galit Alter, Elisabeth K. Nyakatura, Larry Zeitlin, Julia C. Frei, Frederick W. Holtsberg, Calli M. Lear-Rooney, Jeffrey W. Froude, Pamela J. Glass
The unprecedented 2014-2015 Ebola virus disease (EVD) outbreak in West Africa has highlighted the need for effective therapeutics against filoviruses. Monoclonal antibody (MAb) cocktails have shown great potential as EVD therapeutics; however, the ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ee88021ba53814208117ee432b454d
https://europepmc.org/articles/PMC4702560/
https://europepmc.org/articles/PMC4702560/
Publikováno v:
ACS Infectious Diseases
The Ebolaviruses are members of the family Filoviridae (“filoviruses”) and cause severe hemhorragic fever with human case fatality rates as high as 90%. Infection requires attachment of the viral particle to cells and triggering of membrane fusio
Publikováno v:
EURO Journal on Transportation and Logistics, Vol 12, Iss , Pp 100094- (2023)
Collaborative delivery employing drones in last-mile delivery has been an extensively studied topic in recent years. In this paper, it is studied Truck–Drone Delivery Problems (TDDPs) in which a traditional delivery truck is gathered with a drone t
Externí odkaz:
https://doaj.org/article/b4283846f1504b85a29128478a7198c3