Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Julia Brill"'
Publikováno v:
Journal of Neurophysiology. 115:1208-1219
Serotoninergic fibers densely innervate olfactory bulb glomeruli, the first sites of synaptic integration in the olfactory system. Acting through 5HT2Areceptors, serotonin (5HT) directly excites external tufted cells (ETCs), key excitatory glomerular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617f6c242e4650feaa7be1a1afce58b0
https://doi.org/10.1152/jn.00847.2015
https://doi.org/10.1152/jn.00847.2015
Autor:
Minsuk Hyun, Suzanne Evans, Julia Brill, Thomas J. Davidson, Talia N. Lerner, Charu Ramakrishnan, Karl Deisseroth, John R. Huguenard, Joanna Mattis
Publikováno v:
The Journal of Neuroscience. 34:11769-11780
Hippocampal oscillations are critical for information processing, and are strongly influenced by inputs from the medial septum. Hippocamposeptal neurons provide direct inhibitory feedback from the hippocampus onto septal cells, and are therefore like
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dc809c3c8095ae7205d974dbdb079d
https://doi.org/10.1523/jneurosci.5188-13.2014
https://doi.org/10.1523/jneurosci.5188-13.2014
Publikováno v:
The Journal of Neuroscience. 32:11067-11081
Disturbances in corticothalamic circuitry can lead to absence epilepsy. The reticular thalamic nucleus (RTN) plays a pivotal role in that it receives excitation from cortex and thalamus and, when strongly activated, can generate excessive inhibitory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c399a264a3908e9d629ac994d6590c
https://doi.org/10.1523/jneurosci.5604-11.2012
https://doi.org/10.1523/jneurosci.5604-11.2012
Autor:
John R. Huguenard, Julia Brill
Publikováno v:
Cerebral Cortex. 20:2926-2938
Cortical dysplasias frequently underlie neurodevelopmental disorders and epilepsy. Rats with a neonatally induced cortical microgyrus [freeze-lesion (FL)], a model of human polymicrogyria, display epileptiform discharges in vitro. We probed excitator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa985e3afa6479effbba24bae5b0100
https://doi.org/10.1093/cercor/bhq040
https://doi.org/10.1093/cercor/bhq040
Autor:
John R. Huguenard, Julia Brill
Publikováno v:
Journal of Neuroscience. 29:7413-7423
Inhibitory connectivity onto neocortical pyramidal cells was mapped using LSPS (laser-scanning photostimulation/glutamate uncaging). The average onset latency of IPSCs was shorter than that of EPSCs recorded in the same cells, indicating a specific m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a478e749046310dfdae88dcb7862a4
https://doi.org/10.1523/jneurosci.6098-08.2009
https://doi.org/10.1523/jneurosci.6098-08.2009
Publikováno v:
Peptides. 28:250-256
Neuropeptide Y is the ligand of a family of G-protein coupled receptors (Y(1) to Y(6)). In the thalamus, exogenous and endogenously released NPY can shorten the duration of thalamic oscillations in brain slices from P13 to P15 rats, an in vitro model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b43ecd5dce2a155d98d338a01fba18e
https://doi.org/10.1016/j.peptides.2006.08.043
https://doi.org/10.1016/j.peptides.2006.08.043
Publikováno v:
Journal of Neuroscience. 26:6813-6822
Valproate (VPA) can suppress absence and other seizures, but its precise mechanisms of action are not completely understood. We investigated whether VPA influences the expression of neuropeptide Y (NPY), an endogenous anticonvulsant. Chronic VPA admi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae275f9d1d1482dcd061ca50cda34d8
https://doi.org/10.1523/jneurosci.5320-05.2006
https://doi.org/10.1523/jneurosci.5320-05.2006
Publikováno v:
eNeuro
Neocortical pyramidal cells (PYRs) receive synaptic inputs from many types of GABAergic interneurons. Connections between parvalbumin (PV)-positive, fast-spiking interneurons (“PV cells”) and PYRs are characterized by perisomatic synapses and hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdeada0cec6c665b1a57730a47e5131f
https://doi.org/10.1523/eneuro.0142-15.2016
https://doi.org/10.1523/eneuro.0142-15.2016
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Achilles tendon ruptures are common injuries in an otherwise healthy, active population. Several treatment options exist, with both surgical and non-surgical options. Each treatment option has a unique set of risks and harms, whic
Externí odkaz:
https://doaj.org/article/5412daf3fd444446a16b30221486191e
Autor:
Julia Brill, John R. Huguenard, Luis de Lecea, Patricia Bonnavion, Matthew E. Carter, Ramon Huerta
Publikováno v:
Proceedings of the National Academy of Sciences. 109
Current models of sleep/wake regulation posit that Hypocretin (Hcrt)-expressing neurons in the lateral hypothalamus promote and stabilize wakefulness by projecting to subcortical arousal centers. However, the critical downstream effectors of Hcrt neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e324987f8c8f1d5a1edd5e84d3fe3f
https://doi.org/10.1073/pnas.1202526109
https://doi.org/10.1073/pnas.1202526109