Výsledky vyhledávání - "Julia Bichler"

Potent protection of gallic acid against DNA oxidation: Results of human and animal experiments

Autor: Julia Bichler, Michael Kundi, Asima Chakraborty, Karl-Heinz Wagner, Miroslav Mišík, Siegfried Knasmüller, Sandra Sagmeister, Christine Hoelzl, Gerald Haidinger, Tatjana Simic, Walter Jäger, Maria Dusinska, Franziska Ferk, Bettina Grasl-Kraupp, Armen Nersesyan

Publikováno v: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 715:61-71

Gallic acid (3,4,5-trihydroxybenzoic acid, GA) is a constituent of plant derived foods, beverages and herbal remedies. We investigated its DNA protective properties in a placebo controlled human intervention trial in single cell gel electrophoresis e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83fde5bc56e25ff7a8a1207dc8002220
https://doi.org/10.1016/j.mrfmmm.2011.07.010

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Inhalative Exposure to Vanadium Pentoxide Causes DNA Damage in Workers: Results of a Multiple End Point Study

Autor: Eva Valic, Andreas Schaffer, Armen Nersesyan, Karl-Heinz Wagner, Siegfried Knasmüller, Christine Hoelzl, Franziska Ferk, Rolf Schulte-Hermann, Julia Bichler, Veronika Ehrlich, Michael Fenech

Publikováno v: Environmental Health Perspectives

Background Inhalative exposure to vanadium pentoxide (V2O5) causes lung cancer in rodents. Objective The aim of the study was to investigate the impact of V2O5 on DNA stability in workers from a V2O5 factory. Methods We determined DNA strand breaks i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf9eddff3ad7f45a8b476d2cabeda9c7
https://doi.org/10.1289/ehp.11438

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Consumption of Brussels sprouts protects peripheral human lymphocytes against 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and oxidative DNA-damage: results of a controlled human intervention trial

Autor: Julia Bichler, Tatjana Simic, Armen Nersesyan, Christine Hoelzl, Gerhard Sontag, Franziska Ferk, Gerald Haidinger, Hansruedi Glatt, Karel J. Angelis, Siegfried Knasmüller, Walter Meinl, Asima Chakraborty, Michael Kundi

Publikováno v: Molecular Nutrition & Food Research. 52:330-341

To find out if the cancer protective effects of Brussels sprouts seen in epidemiological studies are due to protection against DNA-damage, an intervention trial was conducted in which the impact of vegetable consumption on DNA-stability was monitored

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4b15ad2809bc14c65f371f593c210b
https://doi.org/10.1002/mnfr.200700406

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Coffee consumption protects human lymphocytes against oxidative and 3-amino-1-methyl-5H-pyrido[4,3-b]indole acetate (Trp-P-2) induced DNA-damage: Results of an experimental study with human volunteers

Autor: Rolf Schulte-Hermann, Tatjana Simic, Siegfried Knasmüller, Gerald Haidinger, Franziska Ferk, Julia Bichler, Christine Hoelzl, Karel J. Angelis, Michael Kundi, Christophe Cavin, Asima Chakraborty

Publikováno v: Food and Chemical Toxicology. 45:1428-1436

Aim of the study was to investigate the impact of coffee on DNA-stability in humans. DNA-damage was monitored in lymphocytes of eight individuals with single cell gel electrophoresis assays before and after consumption of 600 ml coffee (400 ml paper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbb5154054980585f6aa90acb5dfdc02
https://doi.org/10.1016/j.fct.2007.02.001

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Use of human-derived liver cell lines for the detection of environmental and dietary genotoxicants; current state of knowledge

Autor: Sebastian Kevekordes, Christine Hoelzl, Volker Mersch-Sundermann, B.J Majer, Siegfried Knasmüller, Wolfgang W. Huber, Firouz Darroudi, Julia Bichler

Publikováno v: Toxicology. 198:315-328

This article gives an overview of the results of genotoxicity tests, which have been conducted within the last 5 years with the human liver cell line HepG2. It is an update of an earlier review from 1998 (by Knasmüller et al.). In addition, a number

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15021120a7ae5643b70156b10dd68bc8
https://doi.org/10.1016/j.tox.2004.02.008

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Xanthohumol, a prenylated flavonoid contained in beer, prevents the induction of preneoplastic lesions and DNA damage in liver and colon induced by the heterocyclic aromatic amine amino-3-methyl-imidazo[4,5-f]quinoline (IQ)

Autor: Bettina Grasl-Kraupp, Armen Nersesyan, Julia Bichler, Metka Filipič, Miroslav Mišík, Franziska Ferk, Bojana Zegura, Wolfgang W. Huber, Siegfried Knasmüller, Elisabeth Haslinger

Publikováno v: Mutation research. 691(1-2)

Xanthohumol (XN) is a hop derived prenylated flavonoid contained in beer. Earlier findings indicated that it has promising chemopreventive properties and protects cells against DNA damage by carcinogens via inhibition of their activation. Furthermore

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c671307f16b6cd30338b3dbf100d8d0
https://pubmed.ncbi.nlm.nih.gov/20547166

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Coffee consumption induces GSTP in plasma and protects lymphocytes against (+/-)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide induced DNA-damage: results of controlled human intervention trials

Autor: Julia Bichler, Maria Uhl, Rainer Schmid, Christophe Cavin, Siegfried Knasmüller, Gerald Haidinger, Hans Steinkellner, Christine Hoelzl, Andrea Gsur, Michael Kundi

Publikováno v: Mutation research. 591(1-2)

A number of animal studies indicate that coffee protects against chemical induction of cancer; also human studies suggest that coffee consumption is inversely related with the incidence of different forms of cancer. The protective effects were attrib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d069a09da3c0fabbb3ac338a92f4800b
https://pubmed.ncbi.nlm.nih.gov/16099480

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