Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Julia Barsony"'
Publikováno v:
Journal of the Endocrine Society
Multiple epidemiologic studies have associated chronic hyponatremia with both osteoporosis and bone fractures. Studies in experimental animals and cultured cells have demonstrated that reducing the extracellular sodium concentration ([Na+]) causes bo
Publikováno v:
The FASEB Journal. 34:1-1
Publikováno v:
Journal of Biological Chemistry. 286:10864-10875
Our recent animal and human studies revealed that chronic hyponatremia is a previously unrecognized cause of osteoporosis that is associated with increased osteoclast numbers in a rat model of the human disease of the syndrome of inappropriate antidi
Publikováno v:
Journal of Bone and Mineral Research. 15:228-236
Our previous studies suggested that increased osteoclast formation and activity in Paget's disease may be related in part to increased responsiveness of highly purified osteoclast precursors to 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3]. However, the ba
Publikováno v:
Journal of Cellular Biochemistry. 100:617-628
Intestinal calcium absorption is a critical step in the maintenance of calcium homeostasis [Fleet, 2006]. It occurs by both paracellular and transcellular pathways [Bronner, 2003; Hoenderop et al., 2005]. The transcellular calcium absorption pathway
Autor:
Carlos Encinas, Julia Barsony, Hong Chen, Rene F. Chun, Songyang Ren, Martin Hewison, Lisa Nguyen, Shaoxing Wu, Mercedes A. Gacad, John S. Adams
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. :461-465
Using vitamin D-resistant New World primates as model of natural diversity for sterol/steroid action and metabolism, two families of novel intracellular vitamin D regulatory proteins have been discovered and their human homologs elucidated. The first
Autor:
Ming Ruan, T. J. Gagne, Csaba Horváth, Béla Kári, Viktória Ferencz, Julia Barsony, Edit I. Buzás, A.R. Mester, András Falus, Lorraine A. Fitzpatrick, Andras Nagy
Publikováno v:
Proceedings of the National Academy of Sciences. 100:6027-6032
Targeted disruption of the histidine decarboxylase gene (HDC −/− ), the only histamine-synthesizing enzyme, led to a histamine-deficient mice characterized by undetectable tissue histamine levels, impaired gastric acid secretion, impaired passive
Autor:
Julia Barsony, Kirsten Prüfer
Publikováno v:
Molecular Endocrinology. 16:1738-1751
Liganded and unliganded vitamin D receptors (VDRs) carry out distinct functions; both types of functions require heterodimerization with retinoid X receptors (RXRs). Our recent studies with fluorescent protein chimeras of VDR and RXR, termed GFP-VDR,
Publikováno v:
Molecular Endocrinology. 16:961-976
Several cell lines, including ROS17/2.8 rat osteosarcoma (ROS) cells, contain functional VDRs and RXRs but are resistant to the antiproliferative effects of calcitriol and retinoids. We explored the role of receptor degradation in this hormone resist
Autor:
Evgenia Pak, Zsolt Orban, Julia Barsony, Susan E. Taymans, Svetlana Pack, Zhengping Zhuang, Constantine A. Stratakis
Publikováno v:
Journal of Bone and Mineral Research. 14:1163-1166
The vitamin D receptor (VDR) is a member of the steroid hormone receptor superfamily of ligand-activated transcription factors. The VDR gene was previously mapped to human chromosome 12q13-12q14, but its precise physical and genetic localization are