Prenylation-dependent Association of Ki-Ras with Microtubules

Autor: Jeffrey M. Gross, Kala Subramanian, Julia A. Thissen, Tobias Meyer, Patrick J. Casey

Publikováno v: Journal of Biological Chemistry. 272:30362-30370

We recently identified a prenyl peptide-binding protein in microsomal membranes from bovine brain (Thissen, J. A., and Casey, P. J. (1993)J. Biol. Chem. 268, 13780–13783). Through a variety of approaches, this binding protein has been identified as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30355454178fbe5cb315cf0e5b40768a
https://doi.org/10.1074/jbc.272.48.30362

Microsomal membranes contain a high affinity binding site for prenylated peptides

Autor: Julia A. Thissen, Patrick J. Casey

Publikováno v: Journal of Biological Chemistry. 268:13780-13783

Prenylation and subsequent processing of many proteins involved in cellular signaling serves to direct and/or anchor these proteins to specific membranes in the cell. One major class of prenylated proteins contains the so-called CAAX motif; such prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::919aca11a346b70d464fb644f65f8975
https://doi.org/10.1016/s0021-9258(19)85170-0

Kinetics of protein farnesyltransferase: sigmoidal vs hyperbolic behavior as a function of assay conditions

Autor: Julia A. Thissen, Patrick J. Casey

Publikováno v: Analytical biochemistry. 243(1)

Protein farnesyl transferase (FTase) catalyzes the addition of a farnesyl isoprenoid to a conserved cysteine residue in Ras and several other key proteins involved in cell regulation. An assay technique commonly used to measure FTase activity involve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff95f23a96aef690c4b216eddfea42b
https://pubmed.ncbi.nlm.nih.gov/8954528

LIST OF CONTRIBUTORS

Autor: C. Wayne Bardin, Eugene A. Berkowitz, David M. Berman, Susan Bonner-Weir, David L. Brautigan, Sondi Brown, Michael J. Brownstein, James T. Bryant, Dennis R. Burholt, E.R. Burns, Kristine M. Cala, Patrick J. Casey, William W. Chu, Donald S. Coffey, S.B. Conway, Daphne L. Davis, Jakob Dupont, Marilyn I. Evans, Stanley Friedman, Masato Fujisawa, Susan Gamble, Susan Garfinkel, D.W. Gietzen, Danling Gu, Joyce B. Higgins, Lyann R. Hodgskin, Beth J. Hoffman, W.G. Hope, Xiaoguo Hu, Anthony Jackson, Gary L. Johnson, L.-M. Kow, Narender Kumar, Charles P. Landrum, Carol A. Lange-Carter, A.H. Lauber, Xingquan Liu, P. Kay Lund, Thomas Maciag, Paul Mak, M.M. McCarthy, Arlene Mercado, John F. Moomaw, Patricia L. Morris, F. Murad, Maria I. New, Ishwar S. Parhar, Alan W. Partin, J.N. Pasley, Tony Pawson, D.W. Pfaff, Chris Pleiman, Sandra L. Polizotto, James S. Prihoda, Igor Prudovsky, P.L. Rayford, David W. Russell, Madhabananda Sar, Nora Sarvetnick, M. Schwanzel-Fukuda, William A. Segraves, Jianping Shi, Richard I. Silver, Phyllis W. Speiser, Elizabeth Stoner, Kalyan Sundaram, Francesca Tarantini, Anice E. Thigpen, Julia A. Thissen, M.A. Thompson-Reece, Donald J. Tindall, Fred W. Turek, Anthony N. Wakim, Jörg Wessendorf, Perrin C. White, W. Christian Wigley, Elizabeth M. Wilson, Choi-iok Wong, D.E. Woolley, Charles Y.-F. Young, Xi Zhan, Fang L. Zhang, Zhong-xun Zhou, Deguang Zhu, Ann Zimrin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::abcc00d91f1705d83f31c98a5b0fb114
https://doi.org/10.1016/b978-0-12-571149-4.50003-9

Enzymatic modification of proteins with a geranylgeranyl isoprenoid

Autor: John F. Moomaw, Patrick J. Casey, Julia A. Thissen

The prenylation of several proteins involved in oncogenesis and signal transduction plays an essential role in regulating their biological activities. Two distinct isoprenoids are known to be involved in this modification, the 15-carbon farnesyl and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a08113bd3b23fbf7ef9371fc9bee6c
https://europepmc.org/articles/PMC52563/