Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Julia A. Balfour"'
Autor:
Julia A. Balfour, Karen L. Goa
Publikováno v:
Drugs. 61:631-638
▴ Bendamustine is a bifunctional alkylating agent with cytotoxic activity against human ovarian and breast cancers in vitro. It shows only partial in vitro cross-resistance with cyclophosphamide, melphalan, carmustine and cisplatin. ▴ Bendamustin
Autor:
Julia A. Balfour, Blair Jarvis
Publikováno v:
CNS Drugs. 14:483-503
Venlafaxine inhibits presynaptic reuptake of both serotonin (5-hydroxytryptamine; 5-HT) and noradrenaline (norepinephrine). Dysregulation of one or both of these neurotransmitters has been implicated in anxiety disorders, which often co-exist with de
Publikováno v:
Drugs. 59:511-518
▴ Alosetron is a potent and highly selective serotonin 5-HT3 receptor antagonist which has been evaluated for the management of irritable bowel syndrome (IBS). It blocked the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal
Autor:
Julia A. Balfour, Harriet M. Lamb
Publikováno v:
Drugs. 59:115-139
Moxifloxacin is an extended-spectrum fluoroquinolone which has improved coverage against Gram-positive cocci and atypical pathogens compared with older fluoroquinolone agents, while retaining good activity against Gram-negative bacteria. The antibact
Publikováno v:
Drugs. 58:79-88
▴ Rituximab is a chimaeric monoclonal antibody which specifically binds to the CD20 antigen on normal and malignant B lymphocytes. It produces antibody-dependent cell- and complement-mediated cytotoxicity in these cells. ▴ Rituximab reduced perip
Autor:
Julia A. Balfour, Harriet M. Lamb
Publikováno v:
Disease Management and Health Outcomes. 6:225-239
Community-acquired pneumonia (CAP) is a common cause of morbidity and mortality and is associated with the consumption of considerable health resources worldwide. Initial treatment of patients with CAP is often empirical. Growing concern about the in
Autor:
Stuart Noble, Julia A. Balfour
Publikováno v:
BioDrugs. 11:359-364
Becaplermin is a recombinant human platelet-derived growth factor B-chain homodimer (rh-PDGF-BB) for topical treatment of full-thickness diabetic neuropathic ulcers and pressure ulcers. rh-PDGF-BB promotes wound healing, probably by increasing granul
Autor:
Nishan S. Gunasekara, Julia A. Balfour
Publikováno v:
Disease Management and Health Outcomes. 5:41-54
Community-acquired pneumonia (CAP) is a common cause of morbidity and mortality and is associated with the consumption of considerable health resources worldwide. Initial treatment of patients with CAP is often empirical. Growing concern about the in
Autor:
Heather D. Langtry, Julia A. Balfour
Publikováno v:
Drugs. 56:273-297
Azithromycin in an azalide antimicrobial agent active in vitro against major pathogens responsible for infections of the respiratory tract, skin and soft tissues in children. Pathogens that are generally susceptible to azithromycin include Haemophilu
Autor:
Caroline M. Perry, Julia A. Balfour
Publikováno v:
Disease Management and Health Outcomes. 4:277-293
HIV disease is a serious global health problem and a major cause of morbidity and mortality worldwide. It has recently been estimated that more than 30 million adults and 1.1 million children are infected with HIV; it is expected that 40 million peop