Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Julia A M, Bakx"'
Autor:
Julia A. M. Bakx, Andreas S. Biebricher, Graeme A. King, Panagiotis Christodoulis, Kata Sarlós, Anna H. Bizard, Ian D. Hickson, Gijs J. L. Wuite, Erwin J. G. Peterman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Here the authors probe the cleavage and gate opening of single-stranded DNA by the human topoisomerase TRR using a unique single-molecule strategy to reveal structural plasticity in response to both double-stranded DNA and the helicase BLM.
Externí odkaz:
https://doaj.org/article/764b1c9c1010460d8e514df34cefdef4
Implementation of 3D Multi-Color Fluorescence Microscopy in a Quadruple Trap Optical Tweezers System
Autor:
Anna E C, Meijering, Julia A M, Bakx, Tianlong, Man, Iddo, Heller, Gijs J L, Wuite, Erwin J G, Peterman
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2478
Recent advances in the design and measurement capabilities of optical tweezers instruments, and especially the combination with multi-color fluorescence detection, have accommodated a dramatic increase in the versatility of optical trapping. Quadrupl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f30acb9ccaed0d2eba0e249e9b2d927e
https://pubmed.ncbi.nlm.nih.gov/36063319
https://pubmed.ncbi.nlm.nih.gov/36063319
Autor:
Andreas S. Biebricher, Gijs J.L. Wuite, Graeme A. King, Dian Spakman, Erwin J.G. Peterman, Julia A M Bakx
Publikováno v:
Nucleic Acids Research
Spakman, D, Bakx, J A M, Biebricher, A S, Peterman, E J G, Wuite, G J L & King, G A 2021, ' Unravelling the mechanisms of Type 1A topoisomerases using single-molecule approaches ', Nucleic acids research, vol. 49, no. 10, pp. 5470-5492 . https://doi.org/10.1093/nar/gkab239
Spakman, D, Bakx, J A M, Biebricher, A S, Peterman, E J G, Wuite, G J L & King, G A 2021, ' Unravelling the mechanisms of Type 1A topoisomerases using single-molecule approaches ', Nucleic acids research, vol. 49, no. 10, pp. 5470-5492 . https://doi.org/10.1093/nar/gkab239
Topoisomerases are essential enzymes that regulate DNA topology. Type 1A family topoisomerases are found in nearly all living organisms and are unique in that they require single-stranded (ss)DNA for activity. These enzymes are vital for maintaining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb0c475cf9cf649e394fdabf2cef2ebe
http://europepmc.org/articles/PMC8191776
http://europepmc.org/articles/PMC8191776
Publikováno v:
Lab Chip
Lab on a Chip, 20(10), 1780-1791. Royal Society of Chemistry
Jiang, Y, Feldman, T, Bakx, J A M, Yang, D & Wong, W P 2020, ' Stretching DNA to twice the normal length with single-molecule hydrodynamic trapping ', Lab on a Chip, vol. 20, no. 10, pp. 1780-1791 . https://doi.org/10.1039/c9lc01028a
Lab on a Chip, 20(10), 1780-1791. Royal Society of Chemistry
Jiang, Y, Feldman, T, Bakx, J A M, Yang, D & Wong, W P 2020, ' Stretching DNA to twice the normal length with single-molecule hydrodynamic trapping ', Lab on a Chip, vol. 20, no. 10, pp. 1780-1791 . https://doi.org/10.1039/c9lc01028a
Single-molecule force spectroscopy has brought many new insights into nanoscale biology, from the functioning of molecular motors, to the mechanical response of soft materials within the cell. Yet in the extreme-force regime, limitations in current a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec217f7ac4ee0a55c68ff2ae2709680b
https://europepmc.org/articles/PMC7239757/
https://europepmc.org/articles/PMC7239757/
Autor:
Mauro Modesti, Anna H. Bizard, Qi Yao, Anna G Ferreté-Bonastre, Kata Sarlós, Ian D. Hickson, Julia A M Bakx, Andreas S. Biebricher, Gijs J.L. Wuite, Erwin J.G. Peterman, Manikandan Paramasivam
Publikováno v:
Sarlós, K, Biebricher, A S, Bizard, A H, Bakx, J A M, Ferreté-Bonastre, A G, Modesti, M, Paramasivam, M, Yao, Q, Peterman, E J G, Wuite, G J L & Hickson, I D 2018, ' Reconstitution of anaphase DNA bridge recognition and disjunction ', Nature Structural and Molecular Biology, vol. 25, no. 9, pp. 868-876 . https://doi.org/10.1038/s41594-018-0123-8
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, Nature Publishing Group, 2018, 25 (9), pp.868-876. ⟨10.1038/s41594-018-0123-8⟩
Nature Structural and Molecular Biology, 2018, 25 (9), pp.868-876. ⟨10.1038/s41594-018-0123-8⟩
Nature Structural and Molecular Biology, 25(9), 868-876. Nature Publishing Group
Nature Structural & Molecular Biology
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, Nature Publishing Group, 2018, 25 (9), pp.868-876. ⟨10.1038/s41594-018-0123-8⟩
Nature Structural and Molecular Biology, 2018, 25 (9), pp.868-876. ⟨10.1038/s41594-018-0123-8⟩
Nature Structural and Molecular Biology, 25(9), 868-876. Nature Publishing Group
Nature Structural & Molecular Biology
International audience; Faithful chromosome segregation requires that the sister chromatids be disjoined completely. Defective disjunction can lead to the persistence of histone-free threads of DNA known as ultra-fine bridges (UFBs) that connect the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf0fe7bef5227d07a61535d8c2d2699
https://doi.org/10.1038/s41594-018-0123-8
https://doi.org/10.1038/s41594-018-0123-8
Publikováno v:
Bakx, J, Cabanas-Danes, J, Peterman, E J G & Wuite, G J L 2018, ' The Interaction between Bacteriophage T7 DNA Polymerase and Gene 2.5 Protein at the Single-Molecule Level ', Biophysical Journal, vol. 114, no. 3, pp. 395A-395A .
Biophysical Journal, 114(3), 395A-395A. Biophysical Society
Biophysical Journal, 114(3), 395A-395A. Biophysical Society
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c19339ea93e1e4aea3e0cfde6de05e
https://research.vu.nl/en/publications/e45c9a8f-acb2-4954-8552-28927a7d9797
https://research.vu.nl/en/publications/e45c9a8f-acb2-4954-8552-28927a7d9797
Autor:
Erwin J.G. Peterman, Longfu Xu, Andreas S. Biebricher, Gijs J.L. Wuite, Julia A M Bakx, Seyda Acar
Publikováno v:
Biophysical Journal. 116:75a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c5e040abc1109008fc1bab042b28bf7
https://doi.org/10.1016/j.bpj.2018.11.444
https://doi.org/10.1016/j.bpj.2018.11.444