Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Julia, Welzenbach"'
Autor:
Katharina L. M. Ruff, Ronja Hollstein, Julia Fazaal, Frederic Thieme, Jan Gehlen, Elisabeth Mangold, Michael Knapp, Julia Welzenbach, Kerstin U. Ludwig
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Non-syndromic cleft lip with/without cleft palate (nsCL/P) is a frequent congenital malformation with multifactorial etiology. While recent genome-wide association studies (GWAS) have identified several nsCL/P risk loci, the functional effec
Externí odkaz:
https://doaj.org/article/154cf794fabb40c193bd2bd85e9d0ed4
Autor:
Nina Ishorst, Leonie Henschel, Frederic Thieme, Dmitriy Drichel, Sugirthan Sivalingam, Sarah L. Mehrem, Ariane C. Fechtner, Julia Fazaal, Julia Welzenbach, André Heimbach, Carlo Maj, Oleg Borisov, Jonas Hausen, Ruth Raff, Alexander Hoischen, Michael Dixon, Alvaro Rada‐Iglesias, Michaela Bartusel, Augusto Rojas‐Martinez, Khalid Aldhorae, Bert Braumann, Teresa Kruse, Christian Kirschneck, Gerrit Spanier, Heiko Reutter, Stefanie Nowak, Lina Gölz, Michael Knapp, Andreas Buness, Peter Krawitz, Markus M. Nöthen, Michael Nothnagel, Tim Becker, Kerstin U. Ludwig, Elisabeth Mangold
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 3, Pp n/a-n/a (2023)
Abstract Background Nonsyndromic cleft lip with/without cleft palate (nsCL/P) is a congenital malformation of multifactorial etiology. Research has identified >40 genome‐wide significant risk loci, which explain less than 40% of nsCL/P heritability
Externí odkaz:
https://doaj.org/article/205be1f83d914d678ac7257527a61a58
Autor:
Hanna K. Zieger, Leonie Weinhold, Axel Schmidt, Manuel Holtgrewe, Stefan A. Juranek, Anna Siewert, Annika B. Scheer, Frederic Thieme, Elisabeth Mangold, Nina Ishorst, Fabian U. Brand, Julia Welzenbach, Dieter Beule, Katrin Paeschke, Peter M. Krawitz, Kerstin U. Ludwig
Publikováno v:
HGG Advances, Vol 4, Iss 1, Pp 100166- (2023)
Summary: Non-syndromic cleft lip with/without cleft palate (nsCL/P) is a highly heritable facial disorder. To date, systematic investigations of the contribution of rare variants in non-coding regions to nsCL/P etiology are sparse. Here, we re-analyz
Externí odkaz:
https://doaj.org/article/b61b5dc4116e41ea98f08ed8d964fc18
Autor:
Julia Welzenbach, Nigel L. Hammond, Miloš Nikolić, Frederic Thieme, Nina Ishorst, Elizabeth J. Leslie, Seth M. Weinberg, Terri H. Beaty, Mary L. Marazita, Elisabeth Mangold, Michael Knapp, Justin Cotney, Alvaro Rada-Iglesias, Michael J. Dixon, Kerstin U. Ludwig
Publikováno v:
HGG Advances, Vol 2, Iss 3, Pp 100038- (2021)
Summary: Non-syndromic cleft lip with or without cleft palate (nsCL/P) is a common congenital facial malformation with a multifactorial etiology. Genome-wide association studies (GWASs) have identified multiple genetic risk loci. However, functional
Externí odkaz:
https://doaj.org/article/0c7e6a95d02a4a9283abd9285a586203
Autor:
Anuhar Chaturvedi, Charu Gupta, Razif Gabdoulline, Nora M. Borchert, Ramya Goparaju, Stefan Kaulfuss, Kerstin Görlich, Renate Schottmann, Basem Othman, Julia Welzenbach, Olaf Panknin, Markus Wagner, Robert Geffers, Arnold Ganser, Felicitas Thol, Michael Jeffers, Andrea Haegebarth, Michael Heuser
Publikováno v:
Haematologica, Vol 106, Iss 2 (2020)
Mutant IDH1 (mIDH1) inhibitors have shown single-agent activity in relapsed/refractory AML, though most patients eventually relapse. We evaluated the efficacy and molecular mechanism of the combination treatment with azacitidine, which is currently t
Externí odkaz:
https://doaj.org/article/64b0bb93a8d94cbca64e4eba9c21cc0f
Autor:
Frederic Thieme, Adrianna Mostowska, Christian P. Schaaf, Nina Ishorst, Kerstin U. Ludwig, Ronja Hollstein, Michael Knapp, J Gehlen, Elisabeth Mangold, L G Stüssel, L Weinhold, Julia Schröder, Alvaro Rada-Iglesias, Magdalena Laugsch, Lara M. Hochfeld, Stefanie Heilmann-Heimbach, Julia Welzenbach, Timo Hess, R Olmos Romero
Publikováno v:
Journal of Dental Research. 101:323-330
Nonsyndromic cleft lip with or without palate (nsCL/P) ranks among the most common human birth defects and has a multifactorial etiology. Human neural crest cells (hNCC) make a substantial contribution to the formation of facial bone and cartilage an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61cf849a55b3440ff931fb00a28160e0
https://doi.org/10.1177/00220345211038203
https://doi.org/10.1177/00220345211038203
Autor:
Hanna K, Zieger, Leonie, Weinhold, Axel, Schmidt, Manuel, Holtgrewe, Stefan A, Juranek, Anna, Siewert, Annika B, Scheer, Frederic, Thieme, Elisabeth, Mangold, Nina, Ishorst, Fabian U, Brand, Julia, Welzenbach, Dieter, Beule, Katrin, Paeschke, Peter M, Krawitz, Kerstin U, Ludwig
Publikováno v:
HGG advances. 4(1)
Non-syndromic cleft lip with/without cleft palate (nsCL/P) is a highly heritable facial disorder. To date, systematic investigations of the contribution of rare variants in non-coding regions to nsCL/P etiology are sparse. Here, we re-analyzed availa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d8235251e5750df65b271f2406438ca
https://pubmed.ncbi.nlm.nih.gov/36589413
https://pubmed.ncbi.nlm.nih.gov/36589413
Autor:
Julia Welzenbach, Christiane Neuhoff, Christian Looft, Karl Schellander, Ernst Tholen, Christine Große-Brinkhaus
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149758 (2016)
The aim of this study was to elucidate the underlying biochemical processes to identify potential key molecules of meat quality traits drip loss, pH of meat 1 h post-mortem (pH1), pH in meat 24 h post-mortem (pH24) and meat color. An untargeted metab
Externí odkaz:
https://doaj.org/article/cab7194513f34e7da63dfaf38af89176
Autor:
Zhen Zhang, Elisabeth Mangold, Michael Knapp, Shelley L. Berger, Yemin Lan, Enrique Lin-Shiao, Julia Welzenbach, Morgan A. Sammons, Katherine A. Alexander, Kerstin U. Ludwig
Publikováno v:
Science Advances
Enhancers at critical craniofacial development genes are established by p63 and enriched for SNPs associated with CL/P.
The transcription factor p63 is a key mediator of epidermal development. Point mutations in p63 in patients lead to developme
The transcription factor p63 is a key mediator of epidermal development. Point mutations in p63 in patients lead to developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69f30ea03918dd1ba930fdd4c900f54
http://europepmc.org/articles/PMC6494499
http://europepmc.org/articles/PMC6494499
Autor:
Elisabeth Mangold, Nel Roeleveld, Julia Welzenbach, Khalid Aldhorae, Lambertus A. Kiemeney, Iris A.L.M. van Rooij, Stefaan J. Bergé, Han G. Brunner, Joris Vermeesch, Kerstin U. Ludwig, Tessel E. Galesloot, Greet Hens, Michelle Thonissen, Titiaan Dormaar, Nina Ishorst, Edwin M. Ongkosuwito, Augusto Rojas-Martinez, Carine Carels, Koen Devriendt, Michael Knapp
Publikováno v:
Genes, 10, 12
Genes, 10
Genes
Genes, 10(12):1023. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 10
Issue 12
Genes, 10
Genes
Genes, 10(12):1023. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 10
Issue 12
Non-syndromic cleft lip with or without cleft palate (nsCL/P) ranks among the most common human congenital malformations, and has a multifactorial background in which both exogenous and genetic risk factors act in concert. The present report describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b2b68d2e7fe4795a7fd50d5280d9ef
https://hdl.handle.net/2066/215284
https://hdl.handle.net/2066/215284
