Zobrazeno 1 - 10
of 337
pro vyhledávání: '"Julia, Newton"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The current subjective histopathological assessment of cutaneous melanoma is challenging. The application of image analysis algorithms to histological images may facilitate improvements in workflow and prognostication. To date, several indiv
Externí odkaz:
https://doaj.org/article/3da08e57af8047878667c5665c7883b9
Autor:
Alessia Visconti, Niccolò Rossi, Helena Deriš, Karla A Lee, Maja Hanić, Irena Trbojević-Akmačić, Andrew M. Thomas, Laura A. Bolte, Johannes R. Björk, Jahlisa S. Hooiveld-Noeken, Ruth Board, Mark Harland, Julia Newton-Bishop, Mark Harries, Joseph J. Sacco, Paul Lorigan, Heather M. Shaw, Elisabeth G.E. de Vries, Rudolf S.N. Fehrmann, Rinse K. Weersma, Tim D. Spector, Paul Nathan, Geke A. P. Hospers, Peter Sasieni, Veronique Bataille, Gordan Lauc, Mario Falchi
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of melanoma and other cancers. However, no reliable biomarker of survival or response has entered the clinic to identify those patients with melanoma who are mo
Externí odkaz:
https://doaj.org/article/50b511b7f9af46e6993f096da9d33865
Autor:
Debora D’Angelo Papaiz, Flávia Eichemberger Rius, Ana Luísa Pedroso Ayub, Clarice S. Origassa, Hemant Gujar, Diogo de Oliveira Pessoa, Eduardo Moraes Reis, Jérémie Nsengimana, Julia Newton‐Bishop, Christopher E. Mason, Daniel J. Weisenberger, Gangning Liang, Miriam Galvonas Jasiulionis
Publikováno v:
Molecular Oncology, Vol 16, Iss 9, Pp 1913-1930 (2022)
In addition to mutations, epigenetic alterations are important contributors to malignant transformation and tumor progression. The aim of this work was to identify epigenetic events in which promoter or gene body DNA methylation induces gene expressi
Externí odkaz:
https://doaj.org/article/f9fbc28b88c041f5a8f4fb1477c14ba8
Autor:
María Victoria Castro, Gastón Alexis Barbero, María Belén Villanueva, Luca Grumolato, Jérémie Nsengimana, Julia Newton-Bishop, Edith Illescas, María Josefina Quezada, Pablo Lopez-Bergami
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-15 (2021)
Abstract Background Receptor tyrosine kinase-like orphan receptor 2 (ROR2) is a Wnt5a receptor aberrantly expressed in cancer that was shown to either suppress or promote carcinogenesis in different tumor types. Our goal was to study the role of ROR2
Externí odkaz:
https://doaj.org/article/4aa18ad8bb6d4dfa887f300feb49a3f7
Autor:
Rafał Pawłowski, Paweł Zalewski, Julia Newton, Agnieszka Piątkowska, Edward Koźluk, Grzegorz Opolski, Katarzyna Buszko
Publikováno v:
Frontiers in Physiology, Vol 13 (2023)
Introduction: Heart Rate Asymmetry (HRA) describes a phenomenon of differences between accelerations and decelerations in human heart rate. Methods used for HRA assessment can be further implemented in the evaluation of asymmetry in blood pressure va
Externí odkaz:
https://doaj.org/article/ffc5a92188ff430fa92e74b346e525a1
Autor:
Sion Glyn-Jones, Muhammad K Javaid, David Beard, Julia Newton, Robert Kerslake, Callum McBryde, Tim Board, Susan J Dutton, Melina Dritsaki, Vikas Khanduja, Magbor Akanni, Shaun Sexton, John Skinner, Nicholas Peckham, Ruth Knight, Ines Rombach, Loretta Davies, Vicki Barber
Publikováno v:
Health Technology Assessment, Vol 26, Iss 43 (2022)
Background: People with avascular necrosis of the hip have very limited treatment options currently available to stop the progression of this disease; this often results in the need for a hip replacement. There is some weak evidence that a class of d
Externí odkaz:
https://doaj.org/article/647de304b2444d81b889edaf5299af8c
Autor:
Niccolò Rossi, Karla A. Lee, Maria V. Bermudez, Alessia Visconti, Andrew Maltez Thomas, Laura A. Bolte, Johannes R. Björk, Laura Kist de Ruijter, Julia Newton-Bishop, Mark Harland, Heather M. Shaw, Mark Harries, Joseph Sacco, Ruth Board, Paul Lorigan, Elisabeth G.E. de Vries, Nicola Segata, Leonie Taams, Sophie Papa, Tim D. Spector, Paul Nathan, Rinse K. Weersma, Geke A.P. Hospers, Rudolf S.N. Fehrmann, Veronique Bataille, Mario Falchi
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104235- (2022)
Summary: Background: Inflammation can modulate tumour growth and progression, and influence clinical response to treatment. We investigated the potential of circulating inflammatory proteins for response stratification of immune checkpoint inhibitor
Externí odkaz:
https://doaj.org/article/2653e1f206bf4483825a0683e7b29ab7
Autor:
Marina Juraleviciute, Jérémie Nsengimana, Julia Newton‐Bishop, Gert J. Hendriks, Ana Slipicevic
Publikováno v:
Cancer Medicine, Vol 10, Iss 8, Pp 2840-2854 (2021)
Abstract MX2 is an interferon inducible gene that is mostly known for its antiviral activity. We have previously demonstrated that MX2 is also associated with the tumorigenesis process in melanoma. However, it remains unknown which molecular mechanis
Externí odkaz:
https://doaj.org/article/7baa4dc159db4d9e97171dddd62a0040
Autor:
Diogo de Oliveira Pessoa, Flávia Eichemberger Rius, Debora D'Angelo Papaiz, Ana Luísa Pedroso Ayub, Alice Santana Morais, Camila Ferreira de Souza, Vinicius Ferreira da Paixão, João Carlos Setubal, Julia Newton-Bishop, Jérémie Nsengimana, Hatylas Azevedo, Eduardo Moraes Reis, Miriam Galvonas Jasiulionis
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 4, Pp 439-455 (2021)
Despite advances in therapeutics, the progression of melanoma to metastasis still confers a poor outcome to patients. Nevertheless, there is a scarcity of biological models to understand cellular and molecular changes taking place along disease progr
Externí odkaz:
https://doaj.org/article/1d64e2887e294afe89e979bfd229adbf
Publikováno v:
Annals of Agricultural and Environmental Medicine, Vol 28, Iss 1, Pp 99-106 (2021)
Introduction and objective The diagnosis of multiple sclerosis (MS) affects the socio-economic aspects of patients’ lives and poses new challenges. The objectives of the study were: 1) to determine selected socio-economic aspects of MS in Poland in
Externí odkaz:
https://doaj.org/article/b1bc54d4ec6a42a9ad34a553cf919d58