Zobrazeno 1 - 10
of 152
pro vyhledávání: '"Julia, Hofmann"'
Autor:
Theresa Hautz, Hubert Hackl, Hendrik Gottschling, Raphael Gronauer, Julia Hofmann, Stefan Salcher, Bettina Zelger, Rupert Oberhuber, Benno Cardini, Annemarie Weissenbacher, Thomas Resch, Jakob Troppmair, Stefan Schneeberger
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105330- (2024)
Summary: Background: A better understanding of the molecular events during liver normothermic machine perfusion (NMP) is warranted to develop a data-based approach for the identification of biomarkers representative of graft quality and posttransplan
Externí odkaz:
https://doaj.org/article/dabf014d3eea4d158514cdf8c8d27c59
Autor:
Simon Zacharias Lahme, Jasper Ole Cirkel, Larissa Hahn, Julia Hofmann, Josefine Neuhaus, Susanne Schneider, Pascal Klein
Publikováno v:
Physical Review Physics Education Research, Vol 20, Iss 2, p 020127 (2024)
The current dropout rate in physics studies in Germany is about 60%, with the majority of dropouts occurring in the first year. Consequently, the physics study entry phase poses a significant challenge for many students. Students’ stress perception
Externí odkaz:
https://doaj.org/article/1afcb62346fc462692a12811d56c151c
Autor:
Julia Hofmann, Alexander Kofler, Melanie Schartner, Madita L. Buch, Martin Hermann, Bettina Zelger, Dietmar Öfner, Rupert Oberhuber, Theresa Hautz, Stefan Schneeberger, Andras T. Meszaros
Publikováno v:
Transplant International, Vol 37 (2024)
Organ quality can be assessed prior to transplantation, during normothermic machine perfusion (NMP) of the liver. Evaluation of mitochondrial function by high-resolution respirometry (HRR) may serve as a viability assessment concept in this setting.
Externí odkaz:
https://doaj.org/article/887bb2486fd3475688be16b8f09f2135
Autor:
Andras T. Meszaros, Annemarie Weissenbacher, Melanie Schartner, Tim Egelseer-Bruendl, Martin Hermann, Jasmin Unterweger, Christa Mittelberger, Beatrix A. Reyer, Julia Hofmann, Bettina G. Zelger, Theresa Hautz, Thomas Resch, Christian Margreiter, Manuel Maglione, Timea Komlódi, Hanno Ulmer, Benno Cardini, Jakob Troppmair, Dietmar Öfner, Erich Gnaiger, Stefan Schneeberger, Rupert Oberhuber
Publikováno v:
Transplant International, Vol 37 (2024)
Donor organ biomarkers with sufficient predictive value in liver transplantation (LT) are lacking. We herein evaluate liver viability and mitochondrial bioenergetics for their predictive capacity towards the outcome in LT. We enrolled 43 consecutive
Externí odkaz:
https://doaj.org/article/0fa1744622fe42b993bcf6d4d4930586
Autor:
Julia Hofmann
Julia Hofmann konzipiert in diesem Open Access Buch ein Physiologiemodell für die präzise Simulation bestimmter Verletzungsfolgen und deren Behandlung in einer Computerspielumgebung. Ihre Ergebnisse leisten einen wichtigen Beitrag, um die Ausbildun
Autor:
Ayesha Sen, Sebastian Kallabis, Felix Gaedke, Christian Jüngst, Julia Boix, Julian Nüchel, Kanjanamas Maliphol, Julia Hofmann, Astrid C. Schauss, Marcus Krüger, Rudolf J. Wiesner, David Pla-Martín
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Mitochondrial quality control mechanisms prevent damage accumulation, including in mitochondrial DNA (mtDNA). Here, Sen et al. show that altered mtDNA elicits local rearrangements in mitochondrial membrane potential and cristae structure, with mtDNA
Externí odkaz:
https://doaj.org/article/09a00f8e2ea74f67a21ec565d68bba22
Autor:
Andras T. Meszaros, Julia Hofmann, Madita L. Buch, Benno Cardini, Theresia Dunzendorfer-Matt, Florian Nardin, Michael J. Blumer, Margot Fodor, Martin Hermann, Bettina Zelger, Giorgi Otarashvili, Melanie Schartner, Annemarie Weissenbacher, Rupert Oberhuber, Thomas Resch, Jakob Troppmair, Dietmar ..fner, Heinz Zoller, Herbert Tilg, Erich Gnaiger, Theresa Hautz, Stefan Schneeberger
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104311- (2022)
Summary: Background: Reliable biomarkers for organ quality assessment during normothermic machine perfusion (NMP) are desired. ATP (adenosine triphosphate) production by oxidative phosphorylation plays a crucial role in the bioenergetic homeostasis o
Externí odkaz:
https://doaj.org/article/e529ae879efe4ad79d300a1b0ac02665
Autor:
Julia Hofmann, Andras T. Meszaros, Madita L. Buch, Florian Nardin, Verena Hackl, Carola J. Strolz, Bettina Zelger, Margot Fodor, Benno Cardini, Rupert Oberhuber, Thomas Resch, Annemarie Weissenbacher, Jakob Troppmair, Stefan Schneeberger, Theresa Hautz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9536 (2023)
The majority of organs used for liver transplantation come from brain-dead donors (DBD). In order to overcome the organ shortage, increasingly donation after circulatory death (DCD) organs are also considered. Since normothermic machine perfusion (NM
Externí odkaz:
https://doaj.org/article/d30526cf21bd4e32a3e3286c4e2ab235
Autor:
Franka Messner, Marco Thurner, Jule Müller, Michael Blumer, Julia Hofmann, Rainer Marksteiner, Sebastien Couillard-Despres, Jakob Troppmair, Dietmar Öfner, Stefan Schneeberger, Theresa Hautz
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-15 (2021)
Abstract Background Muscle is severely affected by ischemia/reperfusion injury (IRI). Quiescent satellite cells differentiating into myogenic progenitor cells (MPC) possess a remarkable regenerative potential. We herein established a model of local a
Externí odkaz:
https://doaj.org/article/74a4fedf37974a51a18b663d56e42066
Novel, Innovative Models to Study Ischemia/Reperfusion-Related Redox Damage in Organ Transplantation
Autor:
Julia Hofmann, Marlene Pühringer, Sabrina Steinkellner, Aline-Sophie Holl, Andras T. Meszaros, Stefan Schneeberger, Jakob Troppmair, Theresa Hautz
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 31 (2022)
The implementation of ex vivo organ machine perfusion (MP) into clinical routine undoubtedly helped to increase the donor pool. It enables not just organ assessment, but potentially regeneration and treatment of marginal organs in the future. During
Externí odkaz:
https://doaj.org/article/79ac523de8e745a49113b840b2af5604