Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Juli D Uhl"'
Publikováno v:
PLoS Genetics, Vol 12, Iss 4, p e1005981 (2016)
cis-regulatory modules (CRMs) generate precise expression patterns by integrating numerous transcription factors (TFs). Surprisingly, CRMs that control essential gene patterns can differ greatly in conservation, suggesting distinct constraints on TF
Externí odkaz:
https://doaj.org/article/39594b840e434e9681ad6da298abea72
Autor:
Maura McGrail, Julia M Hatler, Xianyan Kuang, Hsin-Kai Liao, Kishore Nannapaneni, Kristin E Noack Watt, Juli D Uhl, David A Largaespada, Erik Vollbrecht, Todd E Scheetz, Adam J Dupuy, Jesse M Hostetter, Jeffrey J Essner
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18826 (2011)
Large-scale sequencing of human cancer genomes and mouse transposon-induced tumors has identified a vast number of genes mutated in different cancers. One of the outstanding challenges in this field is to determine which genes, when mutated, contribu
Externí odkaz:
https://doaj.org/article/2527c50033bc4acc9c059bfb44b5c54e
Publikováno v:
Journal of Science Education and Technology. 31:117-128
Constructed response (CR) assessments allow students to demonstrate understanding of complex topics and provide teachers with deeper insight into student thinking. Computer scoring models (CSMs) remove the barrier of increased time and effort, making
Autor:
Mark Urban-Lurain, Rosa A. Moscarella, Kamali N. Sripathi, Juli D. Uhl, Kevin C. Haudek, Jenifer N. Saldanha, John Merrill
Publikováno v:
Biochemistry and Molecular Biology Education
The core concept of genetic information flow was identified in recent calls to improve undergraduate biology education. Previous work shows that students have difficulty differentiating between the three processes of the Central Dogma (CD; replicatio
Autor:
Arya Zandvakili, Ian Campbell, Yuntao Charlie Song, Joseph Salomone, Brian Gebelein, Juli D. Uhl
Publikováno v:
Developmental Biology. 445:226-236
During development diverse transcription factor inputs are integrated by cis-regulatory modules (CRMs) to yield cell-specific gene expression. Defining how CRMs recruit the appropriate combinations of factors to either activate or repress gene expres
Publikováno v:
CBE Life Sciences Education
The focus of biology education has shifted from memorization to conceptual understanding of core biological concepts such as matter and energy relationships. To examine undergraduate learning about matter and energy, we incorporated constructed-respo
Autor:
Juli D. Uhl
During embryonic development, the somatic gonad precursors become populated by the primordial germ cells. While many genes have been identified, the highly regulated process of germ cell migration across the primordial midgut epithelium is not well c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc1235249823c17d10002ae51aa97dc3
https://doi.org/10.31274/rtd-180813-16699
https://doi.org/10.31274/rtd-180813-16699
Hox genes encode a family of transcription factors that, despite having similarin vitroDNA binding preferences, regulate distinct genetic programs along the metazoan anterior-posterior axis. To better define mechanisms of Hox specificity, we compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::613332e73bb5094f218a6b68c97f9eb9
https://doi.org/10.1101/373308
https://doi.org/10.1101/373308
Autor:
Isaiah J. Rolle, David A. Richards, Candi L. LaSarge, Raymund Y. K. Pun, Brian L. Murphy, Katherine D. Holland, Bethany E. Hosford, Christian R. Faulkner, Steve C. Danzer, Stefanie L. Bronson, Jules M. Rosen, Juli D. Uhl, Sarah N. Schmeltzer
Publikováno v:
Neuron. 75:1022-1034
SummaryThe dentate gyrus is hypothesized to function as a “gate,” limiting the flow of excitation through the hippocampus. During epileptogenesis, adult-generated granule cells (DGCs) form aberrant neuronal connections with neighboring DGCs, disr
Autor:
Kuan Shen Wong, Vikram Kohli, Saulius Sumanas, Juli D. Uhl, Wynn G. Hunter, Sharina Palencia-Desai, Megan S. Rost, Kira Rehn
Publikováno v:
Developmental Biology. 361(2):377-391
Endocardial cells form the inner endothelial layer of the heart tube, surrounded by the myocardium. Signaling pathways that regulate endocardial cell specification and differentiation are largely unknown and the origin of endocardial progenitors is s