Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Julián Taranda"'
Autor:
Mariano N. Di Guilmi, Ana Belén Elgoyhen, Carolina Wedemeyer, Paul A. Fuchs, Jimena A. Ballestero, Stéphane F. Maison, Marcelo J. Moglie, Julián Taranda, Eleonora Katz, Lucas G. Vattino, M. Charles Liberman
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Gain control of the auditory system operates at multiple levels. Cholinergic medial olivocochlear (MOC) fibers originate in the brainstem and make synaptic contacts at the base of the outer hair cells (OHCs), the final targets of several feedback loo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3c3bef893ed97a63d16d0d446293f5
https://doi.org/10.1523/jneurosci.2528-17.2018
https://doi.org/10.1523/jneurosci.2528-17.2018
Publikováno v:
Developmental Neurobiology. 69:931-949
Although the synaptogenic program for cholinergic synapses of the neuromuscular junction is well known, little is known of the identity or dynamic expression patterns of proteins involved in non-neuromuscular nicotinic synapse development. We have pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76bb15e72892fddd256ca6de1b1448e6
https://doi.org/10.1002/dneu.20753
https://doi.org/10.1002/dneu.20753
Autor:
Julián Taranda, Douglas E. Vetter, Flavio S. J. de Souza, Marcela Lipovsek, Hakim Hiel, Carolina Wedemeyer, Eleonora Katz, Jimena A. Ballestero, Paul A. Fuchs, M. Eugenia Gómez-Casati, A. Belén Elgoyhen
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Efferent inhibition of cochlear hair cells is mediated by α9α10 nicotinic cholinergic receptors (nAChRs) functionally coupled to calcium-activated, small conductance (SK2) potassium channels. Before the onset of hearing, efferent fibers transiently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29cc9b37dd1c0ec923c7245a1db0e89
https://doi.org/10.1007/s10162-009-0173-z
https://doi.org/10.1007/s10162-009-0173-z
Autor:
Stéphane F. Maison, Vidya Murthy, Julián Taranda, M. Charles Liberman, Douglas E. Vetter, Chris T. Bond, Nadeem Haque, John P. Adelman, A. Belén Elgoyhen
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Cochlear hair cells use SK2 currents to shape responses to cholinergic efferent feedback from the brain. Using SK2-/- mice, we demonstrate that, in addition to their previously defined role in modulating hair cell membrane potentials, SK2 channels ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c51e124c9c752d2dc57e535e295b7a0
https://doi.org/10.1016/j.mcn.2008.08.011
https://doi.org/10.1016/j.mcn.2008.08.011
Autor:
Julián Taranda, Rubén P. Laguens, Hernán García-Rivello, Martin Vila-Petroff, Cary Lai, Matilde Said, Patricia Cabeza-Meckert, Ju Chen, Cecilia M. Hertig, Kevin C K Lloyd, Sergio Ghio, Jorge Scaglione
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 289:H1153-H1160
The neuregulin receptor tyrosine kinase Erb-b4, initially linked to early cardiac development, is shown here to play a critical role in adult cardiac function. In wild-type mice, Erb-b4 protein localized to Z lines and to intercalated disks, suggesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9169984448730a590f04ae42e0a5d7
https://doi.org/10.1152/ajpheart.00048.2005
https://doi.org/10.1152/ajpheart.00048.2005
Publikováno v:
Developmental neurobiology. 69(14)
Although the synaptogenic program for cholinergic synapses of the neuromuscular junction is well known, little is known of the identity or dynamic expression patterns of proteins involved in non-neuromuscular nicotinic synapse development. We have pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::550232425d4585fba82e7ad6994f2792
https://pubmed.ncbi.nlm.nih.gov/19790106
https://pubmed.ncbi.nlm.nih.gov/19790106
Autor:
Eleonora Katz, Julián Taranda, A. Belén Elgoyhen, Jim Boulter, Jimena A. Ballestero, M. Charles Liberman, Douglas E. Vetter, Paul A. Fuchs, Jessica Savino, Stéphane F. Maison
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS Biology, Vol 7, Iss 1, p e18 (2009)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS Biology, Vol 7, Iss 1, p e18 (2009)
The transduction of sound in the auditory periphery, the cochlea, is inhibited by efferent cholinergic neurons projecting from the brainstem and synapsing directly on mechanosensory hair cells. One fundamental question in auditory neuroscience is wha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffdd240698f5ae0a9e13be1af0dc01bc
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1000018
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1000018
Autor:
Marcela Lipovsek, Eleonora Katz, Julián Taranda, Ana Belén Elgoyhen, Viviana Dalamon, Carolina Wedemeyer, María Eugenia Gómez-Casati
Publikováno v:
Journal of the Association for Research in Otolaryngology : JARO. 10(2)
Cochlear inner hair cells (IHCs) release neurotransmitter onto afferent auditory nerve fibers in response to sound stimulation. During early development, synaptic transmission is triggered by spontaneous Ca2+ spikes which are modulated by an efferent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3cba38ee01a9684e0757c0ed4398d86
https://pubmed.ncbi.nlm.nih.gov/19252947
https://pubmed.ncbi.nlm.nih.gov/19252947
Autor:
Julián Taranda, Neil S. Millar, Paola V. Plazas, Eleonora Katz, Jimena A. Ballestero, A. Belén Elgoyhen, Sebastian Kracun, María Eugenia Gómez-Casati, Carla V. Rothlin
Publikováno v:
Molecular pharmacology. 68(3)
In this study, we report the effects of the quinoline derivatives quinine, its optical isomer quinidine, and chloroquine on alpha9alpha10-containing nicotinic acetylcholine receptors (nAChRs). The compounds blocked acetylcholine (ACh)-evoked response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd154d7faf669940408b6ad6c6caa7f0
https://pubmed.ncbi.nlm.nih.gov/15955868
https://pubmed.ncbi.nlm.nih.gov/15955868
Autor:
Julian Taranda, Grinu Mathew, Kaitlin Watrud, Nour El-Amine, Matthew F. Lee, Corey Elowsky, Anastasiia Bludova, Sintia Escobar Avelar, Dawid G. Nowak, Tse-Luen Wee, John E. Wilkinson, Lloyd C. Trotman, Pavel Osten
Publikováno v:
Cell Reports, Vol 37, Iss 7, Pp 110027- (2021)
Summary: Early steps of cancer initiation and metastasis, while critical for understanding disease mechanisms, are difficult to visualize and study. Here, we describe an approach to study the processes of initiation, progression, and metastasis of pr
Externí odkaz:
https://doaj.org/article/89cbad6d853b4185be074d68ba31ccb4