Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Julián Ernesto Nicolás Gulin"'
Autor:
Julián Ernesto Nicolás Gulin, Margarita María Catalina Bisio, Daniela Rocco, Jaime Altcheh, María Elisa Solana, Facundo García-Bournissen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Drug repurposing and combination therapy have been proposed as cost-effective strategies to improve Chagas disease treatment. Miltefosine (MLT), a synthetic alkylphospholipid initially developed for breast cancer and repositioned for leishmaniasis, i
Externí odkaz:
https://doaj.org/article/5e0cdc32c7e14717bfa3400ac03bf18c
Publikováno v:
Laboratory Animal Research, Vol 36, Iss 1, Pp 1-7 (2020)
Abstract Background In animal research, “refinement” refers to modifications of husbandry or experimental procedures to enhance animal well-being and minimize or eliminate pain and distress. Evaluation of drug efficacy in mice models, such as tho
Externí odkaz:
https://doaj.org/article/db111a7583db4ce993356c2a0cb7d85e
Autor:
Jean-Yves Brossas, Ballering Griselda, Margarita Bisio, Jeremy Guihenneuc, Julián Ernesto Nicolás Gulin, Stéphane Jauréguiberry, François-Xavier Lescure, Arnaud Fekkar, Dominique Mazier, Jaime Altcheh, Luc Paris
Publikováno v:
Pathogens, Vol 10, Iss 11, p 1455 (2021)
Chagas disease is a debilitating and often fatal pathology resulting from infection by the protozoan parasite Trypanosoma cruzi. In its recommendations, the World Health Organization states that the diagnosis of T. cruzi infection is usually based on
Externí odkaz:
https://doaj.org/article/9ffd31c262d243a8bf344d4701317d77
Autor:
Jean-Yves Brossas, Julián Ernesto Nicolás Gulin, Margarita Maria Catalina Bisio, Manuel Chapelle, Carine Marinach-Patrice, Mallaury Bordessoules, George Palazon Ruiz, Jeremy Vion, Luc Paris, Jaime Altcheh, Dominique Mazier
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185504 (2017)
BACKGROUND:Chagas disease is a debilitating often fatal disease resulting from infection by the protozoan parasite Trypanosoma cruzi. Chagas disease is endemic in 21 countries of the Americas, and it is an emerging disease in other countries as a res
Externí odkaz:
https://doaj.org/article/b7a1f2ba14df46c4b931ce508d9e539f
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 11, p e0004194 (2015)
Publication of accurate and detailed descriptions of methods in research articles involving animals is essential for health scientists to accurately interpret published data, evaluate results and replicate findings. Inadequate reporting of key aspect
Externí odkaz:
https://doaj.org/article/27c0b93adf6c4c2da65e362c33cc2e6d
Publikováno v:
Laboratory Animal Research, Vol 36, Iss 1, Pp 1-7 (2020)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Laboratory Animal Research
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Laboratory Animal Research
Background: In animal research, "refinement" refers to modifications of husbandry or experimental procedures to enhance animal well-being and minimize or eliminate pain and distress. Evaluation of drug efficacy in mice models, such as those used to s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17867253718d82e021c32572a94770b0
http://link.springer.com/article/10.1186/s42826-020-00071-z
http://link.springer.com/article/10.1186/s42826-020-00071-z
Autor:
Pamela Cribb, Julián Ernesto Nicolás Gulin, Victoria Lucia Alonso, Facundo Garcia-Bournissen, Daniela Marisa Rocco, Jaime Altcheh
Publikováno v:
Paediatrics Publications
There is an urgent need to develop safer and more effective drugs for Chagas disease, as the current treatment relies on benznidazole (BZ) and nifurtimox (NFX). Using the Trypanosoma cruzi Dm28c strain genetically engineered to express the Escherichi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac3a3be9827b954b141fdd20df070fb
https://doi.org/10.1093/biomethods/bpab004
https://doi.org/10.1093/biomethods/bpab004
Autor:
S. Jauréguiberry, Margarita Bisio, Dominique Mazier, Ballering Griselda, Luc Paris, Julián Ernesto Nicolás Gulin, Jaime Altcheh, Jean-Yves Brossas, François-Xavier Lescure, Jeremy Guihenneuc, Arnaud Fekkar
Publikováno v:
Pathogens
Pathogens, MDPI, 2021, 10 (11), pp.1455. ⟨10.3390/pathogens10111455⟩
Volume 10
Issue 11
Pathogens, Vol 10, Iss 1455, p 1455 (2021)
Pathogens, MDPI, 2021, 10 (11), pp.1455. ⟨10.3390/pathogens10111455⟩
Volume 10
Issue 11
Pathogens, Vol 10, Iss 1455, p 1455 (2021)
Chagas disease is a debilitating and often fatal pathology resulting from infection by the protozoan parasite Trypanosoma cruzi. In its recommendations, the World Health Organization states that the diagnosis of T. cruzi infection is usually based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca19ddfea9ed114d421be3b63c664554
https://hal.sorbonne-universite.fr/hal-03447737/document
https://hal.sorbonne-universite.fr/hal-03447737/document
Autor:
Julián Ernesto Nicolás, Gulin, Daniela Marisa, Rocco, Victoria, Alonso, Pamela, Cribb, Jaime, Altcheh, Facundo, García-Bournissen
Publikováno v:
Biology Methods & Protocols
There is an urgent need to develop safer and more effective drugs for Chagas disease, as the current treatment relies on benznidazole (BZ) and nifurtimox (NFX). Using the Trypanosoma cruzi Dm28c strain genetically engineered to express the Escherichi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4bac8b575b1b3b4e0e7a19da9301556e
https://pubmed.ncbi.nlm.nih.gov/34386588
https://pubmed.ncbi.nlm.nih.gov/34386588
Autor:
Mackenzie A. Eagleson, María Elisa Solana, Rodrigo López-Muñoz, Facundo Garcia-Bournissen, Jaime Altcheh, Julián Ernesto Nicolás Gulin
Publikováno v:
Paediatrics Publications
Combination therapy has been proposed as an ideal strategy to reduce drug toxicity and improve treatment efficacy in Chagas disease. Previously, we demonstrated potent in vivo anti-Trypanosoma cruzi activity of voriconazole. In this work, we aimed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4a42ada4af2a2b86909b4fc1ff0f4f0
https://pubmed.ncbi.nlm.nih.gov/32598923
https://pubmed.ncbi.nlm.nih.gov/32598923