Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Julián, Polo Orozco"'
The pH-related metabolic paradigm has rapidly grown in cancer research and treatment. In this contribution, this recent oncological perspective has been laterally assessed for the first time in order to integrate neurodegeneration within the energeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475a51049684ed292e91dc28a933e5b3
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7475, p 7475 (2020)
A brand new approach to the understanding of breast cancer (BC) is urgently needed. In this contribution, the etiology, pathogenesis, and treatment of this disease is approached from the new pH-centric anticancer paradigm. Only this unitarian perspec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::929ac1c15dd055ab7939f68bca76cdcc
Publikováno v:
International Journal of Molecular Sciences
A brand new approach to the understanding of breast cancer (BC) is urgently needed. In this contribution, the etiology, pathogenesis, and treatment of this disease is approached from the new pH-centric anticancer paradigm. Only this unitarian perspec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c7681afa16c946a2bca7e992da471c3f
https://pubmed.ncbi.nlm.nih.gov/33050492
https://pubmed.ncbi.nlm.nih.gov/33050492
Autor:
Julián Polo Orozco, Stefano Fais, Daniel Stanciu, Salvador Harguindey, Jesús Devesa, Kévin Hardonnière, Khalid O. Alfarouk
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1110 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 3, p 1110 (2020)
Despite all efforts, the treatment of breast cancer (BC) cannot be considered to be a success story. The advances in surgery, chemotherapy and radiotherapy have not been sufficient at all. Indeed, the accumulated experience clearly indicates that new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285d066d9957b0f1f7bfd85fec5d1775
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 17, p 4278 (2019)
International Journal of Molecular Sciences, Vol 20, Iss 17, p 4278 (2019)
The treatment of cancer has been slowly but steadily progressing during the last fifty years. Some tumors with a high mortality in the past are curable nowadays. However, there is one striking exception: glioblastoma multiforme. No real breakthrough
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24bf562d185139008541545b869e634e
https://pubmed.ncbi.nlm.nih.gov/31480530
https://pubmed.ncbi.nlm.nih.gov/31480530
Autor:
H H Bashir Adil, Cyril Rauch, Abdel Khalig Muddathir, Muntaser E. Ibrahim, Gamal O. Elhassan, Khalid O. Alfarouk, Julián Polo Orozco, Stephan J. Reshkin, Salvador Harguindey, Daniel Verduzco, Rosa Angela Cardone
Publikováno v:
Oncoscience
Cancer cells acquire an unusual glycolytic behavior relative, to a large extent, to their intracellular alkaline pH (pHi). This effect is part of the metabolic alterations found in most, if not all, cancer cells to deal with unfavorable conditions, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f849982510279c8ac091a5717434256
https://doi.org/10.18632/oncoscience.109
https://doi.org/10.18632/oncoscience.109
Autor:
Salvador Harguindey, Gorka Orive, Eduardo Anitua, Rosa Angela Cardone, Khalid O. Alfarouk, Jesús Devesa, Stephan J. Reshkin, Cyril Rauch, Sébastien Roger, Julián Polo Orozco, Pablo Devesa, Daniel Stanciu
Publikováno v:
Seminars in cancer biology. 43
During the last few years, the understanding of the dysregulated hydrogen ion dynamics and reversed proton gradient of cancer cells has resulted in a new and integral pH-centric paradigm in oncology, a translational model embracing from cancer etiopa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062e19e43ac99364d0e63dcdcc9e6cdd
https://pubmed.ncbi.nlm.nih.gov/28193528
https://pubmed.ncbi.nlm.nih.gov/28193528
Autor:
Stephan J. Reshkin, Salvador Harguindey, Jose Luis Arranz, Julián Polo Orozco, Rosa Angela Cardone, Cyril Rauch, Stefano Fais
Publikováno v:
Journal of Translational Medicine
In recent years an increasing number of publications have emphasized the growing importance of hydrogen ion dynamics in modern cancer research, from etiopathogenesis and treatment. A proton [H+]-related mechanism underlying the initiation and progres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f860722fdec86b55a65e3dcae6129162
https://pubmed.ncbi.nlm.nih.gov/24195657
https://pubmed.ncbi.nlm.nih.gov/24195657