Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Jules P P Meijerink"'
Autor:
Emma Kroeze, Michelle M. Kleisman, Lennart A. Kester, Marijn A. Scheijde‐Vermeulen, Edwin Sonneveld, Jessica G. C. Buijs‐Gladdines, Melanie M. Hagleitner, Friederike A. G. Meyer‐Wentrup, Margreet A. Veening, Auke Beishuizen, Jules P. P. Meijerink, Jan L. C. Loeffen, Roland P. Kuiper
Publikováno v:
HemaSphere, Vol 8, Iss 7, Pp n/a-n/a (2024)
Abstract Twenty percent of children with T‐cell lymphoblastic lymphoma (T‐LBL) will relapse and have an extremely poor outcome. Currently, we can identify a genetically low‐risk subgroup in pediatric T‐LBL, yet these high‐risk patients who
Externí odkaz:
https://doaj.org/article/f691a15ba3c94664ba8c567a4dea1811
Autor:
Emma Kroeze, Dilys D. Weijers, Michelle M. Kleisman, Uri Ilan, Reno S. Bladergroen, Rico Hagelaar, Jules P. P. Meijerink, Marjolijn C. J. Jongmans, Jan L. C. Loeffen, Roland P. Kuiper
Publikováno v:
HemaSphere, Vol 8, Iss 5, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/f06e363facb04d1f9c65581e4a74e3cd
Autor:
Valentina Cordo’, Mariska T. Meijer, Rico Hagelaar, Richard R. de Goeij-de Haas, Vera M. Poort, Alex A. Henneman, Sander R. Piersma, Thang V. Pham, Koichi Oshima, Adolfo A. Ferrando, Guido J. R. Zaman, Connie R. Jimenez, Jules P. P. Meijerink
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
No targeted therapy has been approved yet for the treatment of T cell acute lymphoblastic leukemia. Here the authors show that unbiased phosphoproteomic profiling can identify targetable kinases and guide the design of personalized combination treatm
Externí odkaz:
https://doaj.org/article/c5d14de3e81a4a469e7a8481cdc98225
Autor:
Emma Kroeze, Dilys D. Weijers, Melanie M. Hagleitner, Hester A. de Groot-Kruseman, Marjolijn C. J. Jongmans, Roland P. Kuiper, Rob Pieters, Jules P. P. Meijerink, Jan L. C. Loeffen
Publikováno v:
HemaSphere, Vol 6, Iss 1, p e668 (2022)
This study describes the clinical characteristics of a complete Dutch T-cell lymphoblastic lymphoma (T-LBL) cohort, including second primary malignancies and comorbidities. We show that over 10% of patients in this complete T-LBL cohort have been dia
Externí odkaz:
https://doaj.org/article/edb66bd8c25f4a0b9bc5d4598177b458
Autor:
Jordy C. G. van der Zwet, Willem Smits, Jessica G. C. A. M. Buijs-Gladdines, Rob Pieters, Jules P. P. Meijerink
Publikováno v:
HemaSphere, Vol 5, Iss 1, p e513 (2021)
The glucocorticoid receptor NR3C1 is essential for steroid-induced apoptosis, and deletions of this gene have been recurrently identified at disease relapse for acute lymphoblastic leukemia (ALL) patients. Here, we demonstrate that recurrent NR3C1 in
Externí odkaz:
https://doaj.org/article/48d6b385f02f46fc883b6d73aa77e9a9
Autor:
Yunlei Li, Jessica G C A M Buijs-Gladdines, Kirsten Canté-Barrett, Andrew P Stubbs, Eric M Vroegindeweij, Willem K Smits, Ronald van Marion, Winand N M Dinjens, Martin Horstmann, Roland P Kuiper, Rogier C Buijsman, Guido J R Zaman, Peter J van der Spek, Rob Pieters, Jules P P Meijerink
Publikováno v:
PLoS Medicine, Vol 13, Iss 12, p e1002200 (2016)
Pediatric acute lymphoblastic leukemia (ALL) is the most common childhood cancer and the leading cause of cancer-related mortality in children. T cell ALL (T-ALL) represents about 15% of pediatric ALL cases and is considered a high-risk disease. T-AL
Externí odkaz:
https://doaj.org/article/1fa50ae1f8024b568b22d5497f9e3a8f
Autor:
Miriam, Butler, Britt M T, Vervoort, Dorette S, van Ingen Schenau, Lieneke, Jongeneel, Jordy C G, van der Zwet, René, Marke, Jules P P, Meijerink, Blanca, Scheijen, Laurens T, van der Meer, Frank N, van Leeuwen
Publikováno v:
Frontiers in oncology. 12
Although long-term survival in pediatric acute lymphoblastic leukemia (ALL) currently exceeds 90%, some subgroups, defined by specific genomic aberrations, respond poorly to treatment. We previously reported that leukemias harboring deletions or muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::169a2de7238ed1263cf25a7939212fc9
https://pubmed.ncbi.nlm.nih.gov/36119546
https://pubmed.ncbi.nlm.nih.gov/36119546
Autor:
Demi T C, De Winter, Jenneke E, Van Atteveld, Jessica G C A M, Buijs-Gladiness, Rob, Pieters, Sebastian J C M M, Neggers, Jules P P, Meijerink, Marry M, Van den Heuvel-Eibrink
Publikováno v:
Haematologica.
Not available.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::19946630e0ea766cc7ed06683a84650f
https://pubmed.ncbi.nlm.nih.gov/36226491
https://pubmed.ncbi.nlm.nih.gov/36226491
Autor:
Sarah J Stein, Ethan A Mack, Kelly S Rome, Kostandin V Pajcini, Takuya Ohtani, Lanwei Xu, Yunlei Li, Jules P P Meijerink, Robert B Faryabi, Warren S Pear
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155408 (2016)
Trib2 is highly expressed in human T cell acute lymphoblastic leukemia (T-ALL) and is a direct transcriptional target of the oncogenic drivers Notch and TAL1. In human TAL1-driven T-ALL cell lines, Trib2 is proposed to function as an important surviv
Externí odkaz:
https://doaj.org/article/4a24ef311aa44b3886fece58b3199e5d
Autor:
Jordy C G, Van der Zwet, Valentina, Cordo', Jessica G C A M, Buijs-Gladdines, Rico, Hagelaar, Willem K, Smits, Eric, Vroegindeweij, Laura T M, Graus, Vera, Poort, Marloes, Nulle, Rob, Pieters, Jules P P, Meijerink
Publikováno v:
Haematologica.
Physiologic and pathogenic IL7-receptor (IL7R) induced signaling provokes glucocorticoid resistance in a subset of pediatric T-cell acute lymphoblastic leukemia (T-ALL) patients. Activation of downstream STAT5 has been suggested to cause steroid resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8fe7a19033376fd45a0c0b1f0160842
https://pubmed.ncbi.nlm.nih.gov/35734930
https://pubmed.ncbi.nlm.nih.gov/35734930